Guidelines for performing Mendelian randomization investigations [version 2; peer review: 2 approved]

Autor: Burgess, S, Davey Smith, G, Davies, NM, Dudbridge, F, Gill, D, Glymour, MM, Hartwig, FP, Holmes, MV, Minelli, C, Relton, CL, Theodoratou, E

Publikováno v: Wellcome Open Research, Vol 4 (2020)

This paper provides guidelines for performing Mendelian randomization investigations. It is aimed at practitioners seeking to undertake analyses and write up their findings, and at journal editors and reviewers seeking to assess Mendelian randomizati

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https://wellcomeopenresearch.org/articles/4-186/v2

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

Autor: Feitosa, MF, Kraja, AT, Chasman, DI, Sung, YJ, Winkler, TW, Ntalla, I, Guo, X, Franceschini, N, Cheng, CY, Sim, X, Vojinovic, D, Marten, J, Musani, SK, Li, C, Bentley, AR, Brown, MR, Schwander, K, Richard, MA, Noordam, R, Aschard, H, Bartz, TM, Bielak, LF, Dorajoo, R, Fisher, V, Hartwig, FP, Horimoto, ARVR, Lohman, KK, Manning, AK, Rankinen, T, Smith, AV, Tajuddin, SM, Wojczynski, MK, Alver, M, Boissel, M, Cai, Q, Campbell, A, Chai, JF, Chen, X, Divers, J, Gao, C, Goel, A, Hagemeijer, Y, Harris, SE, He, M, Hsu, FC, Jackson, AU, Kähönen, M, Kasturiratne, A, Komulainen, P, Kühnel, B, Laguzzi, F, Luan, J, Matoba, N, Nolte, IM, Padmanabhan, S, Riaz, M, Rueedi, R, Robino, A, Said, MA, Scott, RA, Sofer, T, Stančáková, A, Takeuchi, F, Tayo, BO, Van Der Most, PJ, Varga, TV, Vitart, V, Wang, Y, Ware, EB, Warren, HR, Weiss, S, Wen, W, Yanek, LR, Zhang, W, Zhao, JH, Afaq, S, Amin, N, Amini, M, Arking, DE, Aung, T, Boerwinkle, E

Publikováno v: Feitosa, MF; Kraja, AT; Chasman, DI; Sung, YJ; Winkler, TW; Ntalla, I; et al.(2018). Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. PLoS ONE, 13(6). doi: 10.1371/journal.pone.0198166. UCLA: Retrieved from: http://www.escholarship.org/uc/item/9bn3n17g

© 2018 Public Library of Science. All Rights Reserved. Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP) regulation remains unknown. We hypothesized that a

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http://www.escholarship.org/uc/item/9bn3n17g

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

Autor: Bentley, Amy R, Sung, Yun J, Brown, Michael R, Winkler, Thomas W, Kraja, Aldi T, Ntalla, Ioanna, Schwander, Karen, Chasman, Daniel I, Lim, Elise, Deng, Xuan, Guo, Xiuqing, Liu, Jingmin, Lu, Yingchang, Cheng, Ching-Yu, Sim, Xueling, Vojinovic, Dina, Huffman, Jennifer E, Musani, Solomon K, Li, Changwei, Feitosa, Mary F, Richard, Melissa A, Noordam, Raymond, Baker, Jenna, Chen, Guanjie, Aschard, Hugues, Bartz, Traci M, Ding, Jingzhong, Dorajoo, Rajkumar, Manning, Alisa K, Rankinen, Tuomo, Smith, Albert V, Tajuddin, Salman M, Zhao, Wei, Graff, Mariaelisa, Alver, Maris, Boissel, Mathilde, Chai, Jin Fang, Chen, Xu, Divers, Jasmin, Evangelou, Evangelos, Gao, Chuan, Goel, Anuj, Hagemeijer, Yanick, Harris, Sarah E, Hartwig, Fernando P, He, Meian, Horimoto, Andrea RVR, Hsu, Fang-Chi, Hung, Yi-Jen, Jackson, Anne U, Kasturiratne, Anuradhani, Komulainen, Pirjo, Kuehnel, Brigitte, Leander, Karin, Lin, Keng-Hung, Luan, Jian'an, Lyytikainen, Leo-Pekka, Matoba, Nana, Nolte, Ilja M, Pietzner, Maik, Prins, Bram, Riaz, Muhammad, Robino, Antonietta, Said, M Abdullah, Schupf, Nicole, Scott, Robert A, Sofer, Tamar, Stancakova, Alena, Takeuchi, Fumihiko, Tayo, Bamidele O, van der Most, Peter J, Varga, Tibor V, Wang, Tzung-Dau, Wang, Yajuan, Ware, Erin B, Wen, Wanqing, Xiang, Yong-Bing, Yanek, Lisa R, Zhang, Weihua, Zhao, Jing Hua, Adeyemo, Adebowale, Afaq, Saima, Amin, Najaf, Amini, Marzyeh, Arking, Dan E, Arzumanyan, Zorayr, Aung, Tin, Ballantyne, Christie, Barr, R Graham, Bielak, Lawrence F, Boerwinkle, Eric, Bottinger, Erwin P, Broeckel, Ulrich, Brown, Morris, Cade, Brian E, Campbell, Archie, Canouil, Mickael, Charumathi, Sabanayagam, Chen, Yii-Der Ida, Christensen, Kaare, Concas, Maria Pina, Connell, John M, de las Fuentes, Lisa, de Silva, H Janaka, de Vries, Paul S, Doumatey, Ayo, Duan, Qing, Eaton, Charles B, Eppinga, Ruben N, Faul, Jessica D, Floyd, James S, Forouhi, Nita G, Forrester, Terrence, Friedlander, Yechiel, Gandin, Ilaria, Gao, He, Ghanbari, Mohsen, Gharib, Sina A, Gigante, Bruna, Giulianini, Franco, Grabe, Hans J, Gu, C Charles, Harris, Tamara B, Heikkinen, Sami, Heng, Chew-Kiat, Hirata, Makoto, Hixson, James E, Ikram, M Arfan, Jia, Yucheng, Joehanes, Roby, Johnson, Craig, Jonas, Jost Bruno, Justice, Anne E, Katsuya, Tomohiro, Khor, Chiea Chuen, Kilpelainen, Tuomas O, Koh, Woon-Puay, Kolcic, Ivana, Kooperberg, Charles, Krieger, Jose E, Kritchevsky, Stephen B, Kubo, Michiaki, Kuusisto, Johanna, Lakka, Timo A, Langefeld, Carl D, Langenberg, Claudia, Launer, Lenore J, Lehne, Benjamin, Lewis, Cora E, Li, Yize, Liang, Jingjing, Lin, Shiow, Liu, Ching-Ti, Liu, Jianjun, Liu, Kiang, Loh, Marie, Lohman, Kurt K, Louie, Tin, Luzzi, Anna, Magi, Reedik, Mahajan, Anubha, Manichaikul, Ani W, McKenzie, Colin A, Meitinger, Thomas, Metspalu, Andres, Milaneschi, Yuri, Milani, Lili, Mohlke, Karen L, Momozawa, Yukihide, Morris, Andrew P, Murray, Alison D, Nalls, Mike A, Nauck, Matthias, Nelson, Christopher P, North, Kari E, O'Connell, Jeffrey R, Palmer, Nicholette D, Papanicolau, George J, Pedersen, Nancy L, Peters, Annette, Peyser, Patricia A, Polasek, Ozren, Poulter, Neil, Raitakari, Olli T, Reiner, Alex P, Renstrom, Frida, Rice, Treva K, Rich, Stephen S, Robinson, Jennifer G, Rose, Lynda M, Rosendaal, Frits R, Rudan, Igor, Schmidt, Carsten O, Schreiner, Pamela J, Scott, William R, Sever, Peter, Shi, Yuan, Sidney, Stephen, Sims, Mario, Smith, Jennifer A, Snieder, Harold, Starr, John M, Strauch, Konstantin, Stringham, Heather M, Tan, Nicholas YQ, Tang, Hua, Taylor, Kent D, Teo, Yik Ying, Tham, Yih Chung, Tiemeier, Henning, Turner, Stephen T, Uitterlinden, Andre G, van Heemst, Diana, Waldenberger, Melanie, Wang, Heming, Wang, Lan, Wang, Lihua, Wei, Wen Bin, Williams, Christine A, Sr, Wilson Gregory, Wojczynski, Mary K, Yao, Jie, Young, Kristin, Yu, Caizheng, Yuan, Jian-Min, Zhou, Jie, Zonderman, Alan B, Becker, Diane M, Boehnke, Michael, Bowden, Donald W, Chambers, John C, Cooper, Richard S, de Faire, Ulf, Deary, Ian J, Elliott, Paul, Esko, Tonu, Farrall, Martin, Franks, Paul W, Freedman, Barry I, Froguel, Philippe, Gasparini, Paolo, Gieger, Christian, Horta, Bernardo L, Juang, Jyh-Ming Jimmy, Kamatani, Yoichiro, Kammerer, Candace M, Kato, Norihiro, Kooner, Jaspal S, Laakso, Markku, Laurie, Cathy C, Lee, I-Te, Lehtimaki, Terho, Magnusson, Patrik KE, Oldehinkel, Albertine J, Penninx, Brenda WJH, Pereira, Alexandre C, Rauramaa, Rainer, Redline, Susan, Samani, Nilesh J, Scott, James, Shu, Xiao-Ou, van der Harst, Pim, Wagenknecht, Lynne E, Wang, Jun-Sing, Wang, Ya Xing, Wareham, Nicholas J, Watkins, Hugh, Weir, David R, Wickremasinghe, Ananda R, Wu, Tangchun, Zeggini, Eleftheria, Zheng, Wei, Bouchard, Claude, Evans, Michele K, Gudnason, Vilmundur, Kardia, Sharon LR, Liu, Yongmei, Psaty, Bruce M, Ridker, Paul M, van Dam, Rob M, Mook-Kanamori, Dennis O, Fornage, Myriam, Province, Michael A, Kelly, Tanika N, Fox, Ervin R, Hayward, Caroline, van Duijn, Cornelia M, Tai, E Shyong, Wong, Tien Yin, Loos, Ruth JF, Franceschini, Nora, Rotter, Jerome I, Zhu, Xiaofeng, Bierut, Laura J, Gauderman, W James, Rice, Kenneth, Munroe, Patricia B, Morrison, Alanna C, Rao, Dabeeru C, Rotimi, Charles N, Cupples, L Adrienne, Consortium, COGENT-Kidney, Consortium, EPIC-InterAct, Grp, Understanding Soc Sci, Cohort, Lifelines

Publikováno v: Nature Genetics
Nature Genetics, Nature Publishing Group, 2019, 51 (4), pp.636-648. ⟨10.1038/s41588-019-0378-y⟩
NATURE GENETICS
Nature Genetics, 51(4), 636
Bentley, A R, Sung, Y J, Brown, M R, Winkler, T W, Kraja, A T, Ntalla, I, Schwander, K, Chasman, D I, Lim, E, Deng, X, Guo, X, Liu, J, Lu, Y, Cheng, C-Y, Sim, X, Vojinovic, D, Huffman, J E, Musani, S K, Li, C, Feitosa, M F, Richard, M A, Noordam, R, Baker, J, Chen, G, Aschard, H, Bartz, T M, Ding, J, Dorajoo, R, Manning, A K, Rankinen, T, Smith, A V, Tajuddin, S M, Zhao, W, Graff, M, Alver, M, Boissel, M, Chai, J F, Chen, X, Divers, J, Evangelou, E, Gao, C, Goel, A, Hagemeijer, Y, Harris, S E, Hartwig, F P, He, M, Horimoto, A R V R, Milaneschi, Y, Yuan, J-M, Penninx, B W J H, COGENT-Kidney Consortium, EPIC-InterAct Consortium, Understanding Society Scientific group, Lifelines Cohort, Pereira, C, Rauramaa, R, Redline, S, Samani, N J, Scott, J, Shu, X-O, van der Harst, P, Wagenknecht, L E, Wang, J-S, Wang, Y X, Wareham, N, Watkins, H, Weir, D R, Wickremasinghe, A R, Wu, T, Zeggini, E, Zheng, W, Bouchard, C, Evans, M K, Gudnason, V, Kardia, S L R, Liu, Y, Psaty, B M, Ridker, P M, Van Dam, R M, Hayward, C, van Duijn, C M, Tai, E-S, Wong, T Y, Loos, R J F, Franceschini, N, Rotter, J I, Zhu, X, Bierut, L J, Gauderman, W J, Rice, K M, Munroe, P B, Morrison, A C, Rao, D C, Rotimi, C N & Cupples, L A 2019, ' Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids ', Nature Genetics, vol. 51, no. 4, pp. 636-648 . https://doi.org/10.1038/s41588-019-0378-y
Bentley, A R, Sung, Y J, Brown, M R, Winkler, T W, Kraja, A T, Ntalla, I, Schwander, K, Chasman, D I, Lim, E, Deng, X, Guo, X, Liu, J, Lu, Y, Cheng, C Y, Sim, X, Vojinovic, D, Huffman, J E, Musani, S K, Li, C, Feitosa, M F, Richard, M A, Noordam, R, Baker, J, Chen, G, Aschard, H, Bartz, T M, Ding, J, Dorajoo, R, Manning, A K, Rankinen, T, Smith, A V, Tajuddin, S M, Zhao, W, Graff, M, Alver, M, Boissel, M, Chai, J F, Chen, X, Divers, J, Evangelou, E, Gao, C, Goel, A, Hagemeijer, Y, Harris, S E, Hartwig, F P, He, M, Horimoto, A R V R, Hsu, F C, Christensen, K, Wang, J S, Understanding Society Scientific Group, Lifelines Cohort, COGENT-Kidney Consortium & EPIC-InterAct Consortium 2019, ' Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids ', Nature Genetics, vol. 51, no. 4, pp. 636-648 . https://doi.org/10.1038/s41588-019-0378-y
COGENT-Kidney Consortium & Morris, A P 2019, ' Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids ', Nature Genetics, vol. 51, no. 4, pp. 636-648 . https://doi.org/10.1038/s41588-019-0378-y
Nature Genetics, 51(4), 636-+. Nature Publishing Group
Nature Genetics, 2019, 51 (4), pp.636-648. ⟨10.1038/s41588-019-0378-y⟩
Nature Genetics, 51(4), 636-648. Nature Publishing Group
2019, ' Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids ', Nature Genetics, vol. 51, no. 4, pp. 636-648 . https://doi.org/10.1038/s41588-019-0378-y
Nature genetics

The concentrations of high- and low-density lipoprotein cholesterol and triglycerides are influenced by smoking, but it is unknown whether genetic associations with lipids may be modified by smoking. We conducted a multi-ancestry genome-wide gene-smo

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http://ora.ox.ac.uk/objects/uuid:

Women's health and well-being in five birth cohorts from low- and middle-income countries: Domains and their associations with early-life conditions.

Autor: Hartwig FP; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil., Ataullahjan A; Centre for Global Child Health, Hospital for Sick Children, Toronto, Ontario, Canada., Adair L; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA., Gonçalves H; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil., Horta B; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil., Lee N; USC Office of Population Studies Foundation, University of San Carlos, Cebu, Philippines., Martorell R; Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA., Menezes AMB; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil., Dos Santos Motta JV; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil., Norris S; SAMRC Pathways for Health Research Unit, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Ramirez-Zea M; INCAP Research Center for the Prevention of Chronic Diseases, Institute of Nutrition of Central America and Panama, Guatemala City, Guatemala., Richter L; Department of Science and Innovation, National Research Foundation Centre of Excellence in Human Development, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Bhutta Z; Centre for Global Child Health, Hospital for Sick Children, Toronto, Ontario, Canada.; Institute for Global Health and Development, The Aga Khan University, Karachi, Pakistan., Stein AD; Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA., Victora C; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.; International Center for Equity in Health, Federal University of Pelotas, Pelotas, Brazil.

Publikováno v: Journal of global health [J Glob Health] 2024 Aug 16; Vol. 14, pp. 04137. Date of Electronic Publication: 2024 Aug 16.

Maternal mental health and offspring's IQ: Evidence from two Brazilian birth cohorts.

Autor: Soares PSM; Programa de pós-graduação em Epidemiologia, Universidade Federal de Pelotas, Pelotas, Brazil. Electronic address: pedrosmsoares@hotmail.com., de Barros AJD; Programa de pós-graduação em Epidemiologia, Universidade Federal de Pelotas, Pelotas, Brazil., Dos Santos I; Programa de pós-graduação em Epidemiologia, Universidade Federal de Pelotas, Pelotas, Brazil., Matijasevich A; Programa de pós-graduação em Epidemiologia, Universidade Federal de Pelotas, Pelotas, Brazil; Departamento de Medicina Preventiva, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil., Wehrmeister FC; Programa de pós-graduação em Epidemiologia, Universidade Federal de Pelotas, Pelotas, Brazil., Menezes AMB; Programa de pós-graduação em Epidemiologia, Universidade Federal de Pelotas, Pelotas, Brazil., Gonçalves H; Programa de pós-graduação em Epidemiologia, Universidade Federal de Pelotas, Pelotas, Brazil., Hartwig FP; Programa de pós-graduação em Epidemiologia, Universidade Federal de Pelotas, Pelotas, Brazil.

Publikováno v: Journal of affective disorders [J Affect Disord] 2024 Apr 15; Vol. 351, pp. 151-157. Date of Electronic Publication: 2024 Jan 19.