Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Hartmut Schäfer"'
Autor:
Rubén Gil-Redondo, Ricardo Conde, Chiara Bruzzone, Maria Luisa Seco, Maider Bizkarguenaga, Beatriz González-Valle, Angela de Diego, Ana Laín, Hansjörg Habisch, Christoph Haudum, Nicolas Verheyen, Barbara Obermayer-Pietsch, Sara Margarita, Serena Pelusi, Ignacio Verde, Nádia Oliveira, Adriana Sousa, Amaia Zabala-Letona, Aida Santos-Martin, Ana Loizaga-Iriarte, Miguel Unda-Urzaiz, Jasmin Kazenwadel, Georgy Berezhnoy, Tobias Geisler, Meinrad Gawaz, Claire Cannet, Hartmut Schäfer, Tammo Diercks, Christoph Trautwein, Arkaitz Carracedo, Tobias Madl, Luca Valenti, Manfred Spraul, Shelly C. Lu, Nieves Embade, José M. Mato, Oscar Millet
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Metabolic syndrome (MetS) is a cluster of medical conditions and risk factors correlating with insulin resistance that increase the risk of developing cardiometabolic health problems. The specific criteria for diagnosing MetS vary
Externí odkaz:
https://doaj.org/article/0f7d4a04add1447884a54f4d9ce65b6c
Autor:
Jasmin Kazenwadel, Georgy Berezhnoy, Claire Cannet, Hartmut Schäfer, Tobias Geisler, Anne-Katrin Rohlfing, Meinrad Gawaz, Uta Merle, Christoph Trautwein
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-15 (2023)
Abstract Background Diagnostic approaches like the nuclear magnetic resonance spectroscopy (NMR) based quantification of metabolites, lipoproteins, and inflammation markers has helped to identify typical alterations in the blood serum of COVID-19 pat
Externí odkaz:
https://doaj.org/article/18f49d0ac08c4a6ab88add1ec1b43ffb
Autor:
Georgy Berezhnoy, Rosi Bissinger, Anna Liu, Claire Cannet, Hartmut Schäfer, Katharina Kienzle, Michael Bitzer, Helene Häberle, Siri Göpel, Christoph Trautwein, Yogesh Singh
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundDeep metabolomic, proteomic and immunologic phenotyping of patients suffering from an infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have matched a wide diversity of clinical symptoms with potential biomarkers f
Externí odkaz:
https://doaj.org/article/b1db5699b92f44e995fff750384a84cc
Autor:
Gyuntae Bae, Georgy Berezhnoy, André Koch, Claire Cannet, Hartmut Schäfer, Stefan Kommoss, Sara Brucker, Nicolas Beziere, Christoph Trautwein
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Background: Traditional diagnosis is based on histology or clinical-stage classification which provides no information on tumor metabolism and inflammation, which, however, are both hallmarks of cancer and are directly associated with prognosis and s
Externí odkaz:
https://doaj.org/article/04cc526505d84e9794ad1a8f4cbe9995
Autor:
Afshin Saffari, Claire Cannet, Astrid Blaschek, Andreas Hahn, Georg F. Hoffmann, Jessika Johannsen, Romy Kirsten, Musa Kockaya, Stefan Kölker, Wolfgang Müller-Felber, Andreas Roos, Hartmut Schäfer, Ulrike Schara, Manfred Spraul, Friedrich K. Trefz, Katharina Vill, Wolfgang Wick, Markus Weiler, Jürgen G. Okun, Andreas Ziegler
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-16 (2021)
Abstract Background 5q spinal muscular atrophy (SMA) is a disabling and life-limiting neuromuscular disease. In recent years, novel therapies have shown to improve clinical outcomes. Yet, the absence of reliable biomarkers renders clinical assessment
Externí odkaz:
https://doaj.org/article/d1420f1c464d4e51b184e3fd1fc57e55
Autor:
Chiara Bruzzone, Rubén Gil-Redondo, Marisa Seco, Rocío Barragán, Laura de la Cruz, Claire Cannet, Hartmut Schäfer, Fang Fang, Tammo Diercks, Maider Bizkarguenaga, Beatriz González-Valle, Ana Laín, Arantza Sanz-Parra, Oscar Coltell, Ander López de Letona, Manfred Spraul, Shelly C. Lu, Elisabetta Buguianesi, Nieves Embade, Quentin M. Anstee, Dolores Corella, José M. Mato, Oscar Millet
Publikováno v:
Cardiovascular Diabetology, Vol 20, Iss 1, Pp 1-13 (2021)
Abstract Background Metabolic syndrome (MetS) is a multimorbid long-term condition without consensual medical definition and a diagnostic based on compatible symptomatology. Here we have investigated the molecular signature of MetS in urine. Methods
Externí odkaz:
https://doaj.org/article/fdd2825fb92b43c38b52b9294746026e
Autor:
Rubén Gil-Redondo, Ricardo Conde, Maider Bizkarguenaga, Chiara Bruzzone, Ana Laín, Beatriz González-Valle, Milagros Iriberri, Carlos Ramos-Acosta, Eduardo Anguita, Juan Ignacio Arriaga Lariz, Pedro Pablo España Yandiola, Miguel Ángel Moran, Mario Ernesto Jiménez-Mercado, Leire Egia-Mendikute, María Luisa Seco, Hartmut Schäfer, Claire Cannet, Manfred Spraul, Asís Palazón, Nieves Embade, Shelly C. Lu, Julien Wist, Jeremy K. Nicholson, José M. Mato, Oscar Millet
Publikováno v:
Metabolites, Vol 12, Iss 12, p 1206 (2022)
After SARS-CoV-2 infection, the molecular phenoreversion of the immunological response and its associated metabolic dysregulation are required for a full recovery of the patient. This process is patient-dependent due to the manifold possibilities ind
Externí odkaz:
https://doaj.org/article/fe37ec350d9c413bb4be5f77f4197c58
Autor:
Titus Rössler, Georgy Berezhnoy, Yogesh Singh, Claire Cannet, Tony Reinsperger, Hartmut Schäfer, Manfred Spraul, Manfred Kneilling, Uta Merle, Christoph Trautwein
Publikováno v:
Metabolites, Vol 12, Iss 12, p 1277 (2022)
The complex manifestations of COVID-19 are still not fully decoded on the molecular level. We combined quantitative the nuclear magnetic resonance (NMR) spectroscopy serum analysis of metabolites, lipoproteins and inflammation markers with clinical p
Externí odkaz:
https://doaj.org/article/447a02f4781d49dab5fbbaabada42476
Autor:
Claire Cannet, Andrea Pilotto, Júlio César Rocha, Hartmut Schäfer, Manfred Spraul, Daniela Berg, Peter Nawroth, Christian Kasperk, Gwendolyn Gramer, Dorothea Haas, David Piel, Stefan Kölker, Georg Hoffmann, Peter Freisinger, Friedrich Trefz
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-7 (2020)
Abstract Background Phenylketonuria (PKU; OMIM#261600) is a rare metabolic disorder caused by mutations in the phenylalanine hydroxylase (PAH) gene resulting in high phenylalanine (Phe) in blood and brain. If not treated early this results in intelle
Externí odkaz:
https://doaj.org/article/8b6f46eb86264e03ba005cf5a9db5cf9
Autor:
Max Augustin, Carola Horn, Meryem Seda Ercanoglu, Ute Sandaradura de Silva, Vincent Bondet, Isabelle Suarez, Seung-Hun Chon, Dirk Nierhoff, Elena Knops, Eva Heger, Carlo Vivaldi, Hartmut Schäfer, Mark Oette, Gerd Fätkenheuer, Florian Klein, Darragh Duffy, Michaela Müller-Trutwin, Clara Lehmann
Publikováno v:
Pathogens, Vol 11, Iss 4, p 483 (2022)
(1) Background: The gut-associated lymphatic tissue (GALT) represents the largest lymphoid organ, and is considered to be the largest HIV reservoir. The exact size of the GALT reservoir remains unclear. Several markers, such as the chemokine receptor
Externí odkaz:
https://doaj.org/article/184d86c3e70e495c9bc0e2fe1ae1a64e