Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Hartmut Rütten"'
Autor:
Susanne Miehe, Peter Crause, Thorsten Schmidt, Matthias Löhn, Heinz-Werner Kleemann, Thomas Licher, Werner Dittrich, Hartmut Rütten, Carsten Strübing
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35393 (2012)
TRPC channels are a family of nonselective cation channels that regulate ion homeostasis and intracellular Ca(2+) signaling in numerous cell types. Important physiological functions such as vasoregulation, neuronal growth, and pheromone recognition h
Externí odkaz:
https://doaj.org/article/a524d3afaf774f058c9b8f1286d01e76
Autor:
Thorsten Sadowski, Dominik Linz, Wolfgang Linz, Georg Horstick, Herman Schreuder, Sven Ruf, Hartmut Rütten, Christian Buning, Markus Kohlmann, Klaus Wirth, Katja Kroll
Publikováno v:
Methods and Principles in Medicinal Chemistry. :687-716
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc9afa5bc64fb6def03d241b942c36b2
https://doi.org/10.1002/9783527677047.ch23
https://doi.org/10.1002/9783527677047.ch23
Autor:
Hans-Paul Juretschke, Claudia Neumann-Haefelin, Frans A. van Nieuwenhoven, Marc van Bilsen, Ger J. van der Vusse, Dominik Linz, Anneleen Daniels, Chantal Munts, Thorsten Sadowski, Sven Ruf, Hartmut Rütten
Publikováno v:
European journal of heart failure, 14(2), 193-201. Wiley
Aims Type 2 diabetes mellitus (DM) leads to cardiac dysfunction irrespective of hypertension and coronary artery disease; this is called diabetic cardiomyopathy. Here, we investigated the severity of diabetic cardiomyopathy and myocardial remodelling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d39bd6dc1de3585bc0449d78d469d5
https://doi.org/10.1093/eurjhf/hfr166
https://doi.org/10.1093/eurjhf/hfr166
Autor:
Orhia Ihdene, Susanne Miehe, Isabelle Arnould, Andrea Bieberstein, Hartmut Rütten, Carsten Strübing
Publikováno v:
Journal of Biological Chemistry. 285:12426-12434
TRPC4 and TRPC5 are two closely related members of the mammalian transient receptor potential cation channel family that have been implicated in important physiological functions, such as growth cone guidance and smooth muscle contraction. To further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7e085d8620eed47dc6ec5d4ac57b70
https://doi.org/10.1074/jbc.m109.068304
https://doi.org/10.1074/jbc.m109.068304
Autor:
S Van Linthout, P.M. Becher, Zarah Mohr, H. Peters, S. Uyulmaz, Hartmut Rütten, Dirk Westermann, Alexander Riad, Heinz P. Schultheiss, Carsten Tschöpe, P. Wohlfart
Publikováno v:
Diabetologia. 51:2325-2332
Reduced bioavailability of nitric oxide (NO) is a hallmark of diabetes mellitus-induced vascular complications. In the present study we investigated whether a pharmacological increase of endothelial NO synthase (eNOS) production can restore the impai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7150ea77e150a30e9ab09e26f2dcdb70
https://doi.org/10.1007/s00125-008-1159-9
https://doi.org/10.1007/s00125-008-1159-9
Autor:
Wolfgang Linz, Aurelia Simonaviciene, Ursula Schindler, Stephan R. Orth, Kerstin Benz, Hartmut Rütten, Kerstin Amann
Publikováno v:
Kidney and Blood Pressure Research. 30:224-233
Nitric oxide formation is impaired in chronic renal failure. The renoprotective effects of a nonhypotensive dose of HMR1766, a direct activator of the heme enzyme soluble guanylyl cyclase was studied in comparison to an ACE-i in the remnant kidney mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ec6351bceaa7ac06c72d111a4d04b2
https://doi.org/10.1159/000104091
https://doi.org/10.1159/000104091
Autor:
Hartmut Rütten, Wolfgang Linz, Martin Gerl, Hans-Ludwig Schmidts, Stefan Schäfer, Freni Afkham
Publikováno v:
Journal of the Renin-Angiotensin-Aldosterone System, Vol 7 (2006)
Background. Vasopeptidase inhibition has been shown to be an effective antihypertensive principle but its long-term effects on hypertensive target organ damage are not known. We investigated the myocardial, vascular and renal effects of chronic vasop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e39b41185720101f6f135d947dcb6301
https://doi.org/10.3317/jraas.2006.025
https://doi.org/10.3317/jraas.2006.025
Autor:
Wolfgang Linz, Hartmut Rütten, Markus Bleich, H. Vollert, Andreas E. Busch, Stefan Schäfer, G. Biemer-Daub
Publikováno v:
Diabetologia. 47:98-103
Pharmacological inhibition of the renin angiotensin system has proven clinical efficacy in nephropathies of various origins, including diabetic nephropathy. We tested the effects of the dual inhibition of both angiotensin converting enzyme and neutra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb59ca3da6409e243abe685151c5ccce
https://doi.org/10.1007/s00125-003-1264-8
https://doi.org/10.1007/s00125-003-1264-8
Autor:
Hans-Ludwig Schmidts, Martin Gerl, Markus Bleich, Jochen Huber, Hartmut Rütten, Axel Bube, Gert Ulrich Kürzel, Stefan Schäfer, Andreas E. Busch, Wolfgang Linz
Publikováno v:
Cardiovascular Research. 60:447-454
Background: Blocking the renin–angiotensin system is an established therapeutic principle in diabetic nephropathy. We investigated whether inhibition of both neutral endopeptidase and ACE (vasopeptidase inhibition) can prevent functional and morpho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc906abec57cd0b25bf89b84c224e96
https://doi.org/10.1016/s0008-6363(03)00544-3
https://doi.org/10.1016/s0008-6363(03)00544-3
Autor:
Felix Mahfoud, Benedikt Linz, Thimoteus Speer, Hans-Paul Juretschke, Jonathan Schütze, Mathias Hohl, Hartmut Rütten, Michael Böhm, Ralf Dechend, Thomas Hübschle, Dominik Linz, Jürgen Geisel
Publikováno v:
American journal of hypertension. 28(2)
BACKGROUND: Hypertension and metabolic syndrome (MetS) are associated with increased sympathetic activation possibly contributing to the progression of renal damage and cardiac remodeling. Renal sympathetic denervation (RDN) decreases sympathetic ren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1a906e864a4d3fd3d218c31353a499
https://pubmed.ncbi.nlm.nih.gov/25023205
https://pubmed.ncbi.nlm.nih.gov/25023205