Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Hartmut Kirchherr"'
Autor:
Elke Schaeffeler, Manabu Abe, Hannah Rieger, Matthias Schwab, Mira Schiffhauer, Eberhard Wieland, Maria Shipkova, Patrik Schmidt, Nicolas von Ahsen, Hartmut Kirchherr, Gabriela Zurek
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM)
Background:Variation in metabolism, toxicity and therapeutic efficacy of thiopurine drugs is largely influenced by genetic polymorphisms in the thiopurine S-methyltransferase (TPMT) gene. Determination of TPMT activity is routinely performed in patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b39b08c70d2cca21969c4ed55a0e5943
https://doi.org/10.1515/cclm-2017-0670
https://doi.org/10.1515/cclm-2017-0670
Publikováno v:
labm. 37:167-180
Detection and quantification of synthetic cannabinoids (synonym: cannabimimetics) used as a substitute for natural cannabis has been a real toxicological and forensic issue since 2008. On the basis of a short overview of the pharmacological principle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::193815db261b70d78f4d7789fdfa4514
https://doi.org/10.1515/labmed-2012-0059
https://doi.org/10.1515/labmed-2012-0059
Publikováno v:
Therapeutic Drug Monitoring. 35:313-321
Thiopurine drugs (azathioprine, 6-mercaptopurine) show wide interindividual variability and a narrow therapeutic range thus making therapeutic monitoring of their active metabolite 6-thioguanine nucleotides (6-TGN) desirable. We improved the currentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4348ae195a2aecbfe9bdbd656900c2ee
https://doi.org/10.1097/ftd.0b013e318283ed5d
https://doi.org/10.1097/ftd.0b013e318283ed5d
Autor:
Hartmut Kirchherr
Publikováno v:
Chromatogramme richtig integrieren und bewerten: Ein Praxishandbuch für die HPLC und GC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48316437a7492f5fa0ee17bcef7f0592
https://doi.org/10.1002/9783527622221.ch8
https://doi.org/10.1002/9783527622221.ch8
Autor:
Joerg Steinle, Johannes Fuss, Matthias K. Auer, Beat Lutz, Hartmut Kirchherr, Laura Bindila, Peter Gass
Exercise is rewarding, and long-distance runners have described a runner's high as a sudden pleasant feeling of euphoria, anxiolysis, sedation, and analgesia. A popular belief has been that endogenous endorphins mediate these beneficial effects. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5483c806076ace8a12e684a6c73a6f
https://europepmc.org/articles/PMC4620874/
https://europepmc.org/articles/PMC4620874/
Autor:
Maria Mercedes Uribe, Hubertus Himmerich, Hartmut Kirchherr, Frank M. Schmidt, Nicole Lichtblau
Publikováno v:
International Journal of Neuropsychopharmacology. 16:497-499
Postpartum depression with a prevalence of 10–15% (Gavin et al. 2005) is characterized by social retreat, feelings of hopelessness and guilt as well as the inability to feel gratification in the mother's role. A combined treatment of postpartum dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a40fa30f0b749a148546e14508e7c1
https://doi.org/10.1017/s1461145712000648
https://doi.org/10.1017/s1461145712000648
Publikováno v:
Pharmacopsychiatry. 47
In order to flexibly address high throughput analysis for approx. 430 therapeutic drugs, the key requirements are skilled personnel, appropriate instrumentation including back-ups and minimal instrument downtime. Streamlined sample logistics using a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4ed1a6e056c7c2c6e9d53dd41e8b65f
https://doi.org/10.1055/s-0034-1386821
https://doi.org/10.1055/s-0034-1386821
Publikováno v:
Clinical chemistry. 51(1)
Asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) are derived from posttranslational methylation of arginine residues in proteins and after proteolytic release. Whereas protein methylation appears to be important in RNA binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa5b17236b00bb52656ef14f67783d6
https://pubmed.ncbi.nlm.nih.gov/15613724
https://pubmed.ncbi.nlm.nih.gov/15613724
Publikováno v:
Psychopharmacology. 221:719-720
Positron emission tomography (PET) provides important information in studies centered on the drug plasma concentrations–clinical effectiveness relationship, as it directly allows measuring of drug binding to pharmacologically relevant receptors in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e93626457ed8f335af1f005af4f029
https://doi.org/10.1007/s00213-012-2699-8
https://doi.org/10.1007/s00213-012-2699-8
Autor:
Hartmut Kirchherr
Publikováno v:
Journal of chromatography. 617(1)
A simple and sensitive liquid chromatographic method for the determination of hydrazine in human plasma and serum is described. Samples were prepared in a single-step reaction by protein denaturation with trichloroacetic acid and derivatization to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91302c146971fb56e8f94b27211bd481
https://pubmed.ncbi.nlm.nih.gov/8376531
https://pubmed.ncbi.nlm.nih.gov/8376531