Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Hartmut H. Schmidt"'
Imaging-based diagnosis of sarcopenia for transplant-free survival in primary sclerosing cholangitis
Autor:
Pedram Keshoofi, Philipp Schindler, Florian Rennebaum, Friederike Cordes, Haluk Morgul, Moritz Wildgruber, Hauke S. Heinzow, Andreas Pascher, Hartmut H. Schmidt, Anna Hüsing-Kabar, Michael Praktiknjo, Jonel Trebicka, Leon Louis Seifert
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Imaging-based assessment of sarcopenia is a well-validated prognostic tool for patients with chronic liver disease. However, little is known about its value in patients with primary sclerosing cholangitis (PSC). This cross-section
Externí odkaz:
https://doaj.org/article/5d904cb42d524456aa6fbff3d7cb3343
Autor:
Stefan Schefczyk, Xufeng Luo, Yaojie Liang, Mike Hasenberg, Bernd Walkenfort, Martin Trippler, Jonas Schuhenn, Kathrin Sutter, Mengji Lu, Heiner Wedemeyer, Hartmut H. Schmidt, Ruth Broering
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Hepatitis B virus (HBV)-transgenic mice exhibit competent innate immunity and are therefore an ideal model for considering intrinsic or cell-based mechanisms in HBV pathophysiology. A highly replicative model that has been little used, let a
Externí odkaz:
https://doaj.org/article/d8033cbdd44a4c2e8375ba24f2d4d013
Autor:
Yaojie Liang, Xufeng Luo, Stefan Schefczyk, Lorraine T. Muungani, Hui Deng, Baoju Wang, Hideo A. Baba, Mengji Lu, Heiner Wedemeyer, Hartmut H. Schmidt, Ruth Broering
Publikováno v:
JHEP Reports, Vol 6, Iss 4, Pp 101012- (2024)
Background & Aims: Hepatitis B surface antigen (HBsAg) drives hepatocarcinogenesis. Factors and mechanisms involved in this progression remain poorly defined, hindering the development of effective therapeutic strategies. Therefore, the mechanisms in
Externí odkaz:
https://doaj.org/article/021c294eb0fa4e82a3c04f7fbcee6c73
Autor:
Ayaz Sapuk, Leonie Steinhoff, Kristin Huenninghaus, Katharina Willuweit, Jassin Rashidi Alavijeh, Benedikt Hild, Lucia Asar, Hartmut H. Schmidt, Christoph Schramm
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 2024 (2024)
Bulevirtide (BLV) is approved for the treatment of chronic hepatitis D (CHD). Because only limited long-term experience has been reported, we aimed to evaluate the efficacy and safety of BLV treatment in patients with advanced chronic liver disease (
Externí odkaz:
https://doaj.org/article/9d99b582b695458a9d1559cc5ee2ebc6
Publikováno v:
Journal of Personalized Medicine, Vol 14, Iss 4, p 370 (2024)
Hepatocellular carcinoma (HCC) is a common complication of chronic liver diseases and remains a relevant cause of cancer-related mortality worldwide. The global prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) as a risk
Externí odkaz:
https://doaj.org/article/62d71446a8f44d7ca6ed69dc9cdf8a05
Autor:
Georgios Konstantis, Georgia Tsaousi, Chryssa Pourzitaki, Stefan Kasper-Virchow, Gregor Zaun, Elisavet Kitsikidou, Moritz Passenberg, Vasilis Spyridon Tseriotis, Katharina Willuweit, Hartmut H. Schmidt, Jassin Rashidi-Alavijeh
Publikováno v:
Cancers, Vol 16, Iss 7, p 1280 (2024)
Objective: Gastric carcinoma (GC) is the fifth most commonly diagnosed cancer and the third leading cause of cancer-related deaths globally. The tumor microenvironment plays a significant role in the pathogenesis, prognosis, and response to immunothe
Externí odkaz:
https://doaj.org/article/6ed8dc2832424b6dbc907cdf97d2ee8d
Autor:
Agnese Padula, Raffaella Petruzzelli, Sasha A. Philbert, Stephanie J. Church, Federica Esposito, Severo Campione, Marcello Monti, Filomena Capolongo, Claudia Perna, Edoardo Nusco, Hartmut H. Schmidt, Alberto Auricchio, Garth J.S. Cooper, Roman Polishchuk, Pasquale Piccolo
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 495-504 (2022)
Wilson disease (WD) is a genetic disorder of copper homeostasis, caused by deficiency of the copper transporter ATP7B. Gene therapy with recombinant adeno-associated vectors (AAV) holds promises for WD treatment. However, the full-length human ATP7B
Externí odkaz:
https://doaj.org/article/9b06f42f269f4eb08bec78339d8b5af7
Autor:
Christopher Dietz-Fricke, Frank Tacke, Caroline Zöllner, Münevver Demir, Hartmut H. Schmidt, Christoph Schramm, Katharina Willuweit, Christian M. Lange, Sabine Weber, Gerald Denk, Christoph P. Berg, Julia M. Grottenthaler, Uta Merle, Alexander Olkus, Stefan Zeuzem, Kathrin Sprinzl, Thomas Berg, Florian van Bömmel, Johannes Wiegand, Toni Herta, Thomas Seufferlein, Eugen Zizer, Nektarios Dikopoulos, Robert Thimme, Christoph Neumann-Haefelin, Peter R. Galle, Martin Sprinzl, Ansgar W. Lohse, Julian Schulze zur Wiesch, Jan Kempski, Andreas Geier, Florian P. Reiter, Bernhard Schlevogt, Juliana Gödiker, Wolf Peter Hofmann, Peter Buggisch, Julia Kahlhöfer, Kerstin Port, Benjamin Maasoumy, Markus Cornberg, Heiner Wedemeyer, Katja Deterding
Publikováno v:
JHEP Reports, Vol 5, Iss 4, Pp 100686- (2023)
Background & Aims: Bulevirtide is a first-in-class entry inhibitor of hepatitis B surface antigen. In July 2020, bulevirtide was conditionally approved for the treatment of hepatitis D, the most severe form of viral hepatitis, which frequently causes
Externí odkaz:
https://doaj.org/article/25235c3dba9540059b007583dc50c8da
Autor:
Florian Rennebaum, Claudia Demmig, Hartmut H. Schmidt, Richard Vollenberg, Phil-Robin Tepasse, Jonel Trebicka, Wenyi Gu, Hansjoerg Ullerich, Iyad Kabar, Friederike Cordes
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15431 (2023)
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease often associated with inflammatory bowel disease (IBD), particularly ulcerative colitis (CU), and rarely with Crohn’s disease (CD). Various long-term analyses show differen
Externí odkaz:
https://doaj.org/article/08d21343faba4bdeaa1480ab45d35517
Autor:
Georgios Konstantis, Georgia Tsaousi, Chryssa Pourzitaki, Elisavet Kitsikidou, Dimitrios E. Magouliotis, Sebastian Wiener, Amos Cornelius Zeller, Katharina Willuweit, Hartmut H. Schmidt, Jassin Rashidi-Alavijeh
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 20, p 6541 (2023)
Background: Acute-on-chronic liver failure (ACLF) mostly occurs when there is an acute insult to the liver in patients with pre-existing liver disease, and it is characterized by a high mortality rate. Various therapeutic approaches have been used th
Externí odkaz:
https://doaj.org/article/4326a291f1654481b443075e81fe0696