Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Hartmut Doehner"'
Autor:
Ari M. Melnick, Martin Carroll, Christopher E. Mason, Elisabeth M. Paietta, Michael W. Becker, Richard J. D'Andrea, Hartmut Doehner, Constantine S. Mitsiades, Eugen Dhimolea, Kimihito C. Kawabata, Ceyda Durmaz, Christopher R. Chin, Tak C. Lee, Francine E. Garrett-Bakelman, Cem Meydan, Matt Teater, Meng Li, Cihangir Duy
Supplemental Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f5cfbb31b0403c58a8d2a79717db84
https://doi.org/10.1158/2159-8290.22540768.v1
https://doi.org/10.1158/2159-8290.22540768.v1
Autor:
Ari M. Melnick, Martin Carroll, Christopher E. Mason, Elisabeth M. Paietta, Michael W. Becker, Richard J. D'Andrea, Hartmut Doehner, Constantine S. Mitsiades, Eugen Dhimolea, Kimihito C. Kawabata, Ceyda Durmaz, Christopher R. Chin, Tak C. Lee, Francine E. Garrett-Bakelman, Cem Meydan, Matt Teater, Meng Li, Cihangir Duy
Network analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdbac20e3461c41b2232a959a17a0481
https://doi.org/10.1158/2159-8290.22540750
https://doi.org/10.1158/2159-8290.22540750
Autor:
Ari M. Melnick, Martin Carroll, Christopher E. Mason, Elisabeth M. Paietta, Michael W. Becker, Richard J. D'Andrea, Hartmut Doehner, Constantine S. Mitsiades, Eugen Dhimolea, Kimihito C. Kawabata, Ceyda Durmaz, Christopher R. Chin, Tak C. Lee, Francine E. Garrett-Bakelman, Cem Meydan, Matt Teater, Meng Li, Cihangir Duy
Patients with acute myeloid leukemia (AML) frequently relapse after chemotherapy, yet the mechanism by which AML reemerges is not fully understood. Herein, we show that primary AML cells enter a senescence-like phenotype following chemotherapy in vit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7665ad1a576a4b28fc5a709bc2cc4de1
https://doi.org/10.1158/2159-8290.c.6549469.v1
https://doi.org/10.1158/2159-8290.c.6549469.v1
Autor:
Christian Buske, Daniel Sauter, Mirco Glitscher, Mirja Harms, Hartmut Doehner, Jan Muench, Vijay P.S. Rawat, Eberhard Hildt, Lisa M. Kaiser, Konstanze Doehner
The G protein-coupled receptor (GPCR) and chemokine receptor CXCR4 plays an essential role in tumor initiation and maintenance. This is exemplified in acute myeloid leukemia (AML), where CXCL12-mediated CXCR4 signaling plays a pivotal role for the cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::271e8bf56fce6ae2fed52c5d2071e22c
https://doi.org/10.1101/2021.03.11.434944
https://doi.org/10.1101/2021.03.11.434944
Autor:
Elisabeth Paietta, Christopher E. Mason, Richard J D'Andrea, Martin Carroll, Francine E. Garrett-Bakelman, Constantine S. Mitsiades, Tak C. Lee, Ari Melnick, Cem Meydan, Meng Li, Michael W. Becker, Eugen Dhimolea, Christopher R. Chin, Kimihito Cojin Kawabata, Ceyda Durmaz, Hartmut Doehner, Cihangir Duy, Matt Teater
Publikováno v:
Cancer Discov
Patients with acute myeloid leukemia (AML) frequently relapse after chemotherapy, yet the mechanism by which AML reemerges is not fully understood. Herein, we show that primary AML cells enter a senescence-like phenotype following chemotherapy in vit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff8c128ffb83a5b2096e5a0407617e97
https://europepmc.org/articles/PMC8178167/
https://europepmc.org/articles/PMC8178167/
Autor:
John M. M. Raemaekers, Bastian von Tresckow, Oliver Schmalz, Lenka Šmardová, Peter Borchmann, Bernd Metzner, Hartmut Doehner, Kerstin Schäfer-Eckart, Norbert Schmitz, Andreas Engert, Horst Müller, Dietger Niederwieser, Stephanie Sasse, Magdalena Alram, Thomas Fischer
Publikováno v:
Leukemia & Lymphoma, 57, 1067-73
Leukemia & Lymphoma, 57, 5, pp. 1067-73
Leukemia & Lymphoma, 57, 5, pp. 1067-73
Item does not contain fulltext Only 50% of patients with relapsed Hodgkin lymphoma (HL) can be cured with intensive induction chemotherapy, followed by high-dose chemotherapy (HDCT) and autologous stem cell transplant (ASCT). Based on the results of
Autor:
Stefan Hohaus, Francesco D'Alo', S Groner, Emiliano Fabiani, Hartmut Doehner, Konstanze Doehner, Richard F. Schlenk, D Späth, Giuseppe Leone, Maria Teresa Voso, Francesco Guidi
Publikováno v:
Leukemia. 22:1685-1691
Glutathione S-transferases (GSTs) are phase II detoxification enzymes involved in the metabolism of carcinogens and anticancer drugs, known also to interact with kinase complexes during oxidative or chemical stress-induced apoptosis. We were interest
Autor:
Stephan Stilgenbauer, Hartmut Döhner
Molecular diagnostics are essential in today's management of patients with hematological malignancies. In the current WHO classification of tumors, diseases are defined by morphologic, immunologic and genetic features reflecting the role of molecular
Autor:
Richard K. Wilson, John Easton, Vedant Gupta, Michael Rusch, Konstanze Doehner, Huy Q. Ta, Farhad Ravandi, Tanja A. Gruber, Jinghui Zhang, Jeffrey E. Rubnitz, Sheila A. Shurtleff, Hartmut Doehner, Shann-Ching Chen, Timothy J. Ley, Stephen D. Nimer, Anna Andersson, Xiaoping Su, Elaine R. Mardis, Li Ding, Stacey K. Ogden, Amanda Larson Gedman, Giovanni Cazzaniga, Hagop M. Kantarjian, Cary Koss, Andrea Biondi, Steven M. Kornblau, Ching-Hon Pui, James R. Downing, Jianmin Wang
Abstract 757 Acute Megakaryoblastic Leukemia (AMKL) accounts for ∼10% of childhood acute myeloid leukemia (AML). Although AMKL patients with down syndrome (DS-AMKL) have an excellent 5 year event-free survival (EFS), non-DS-AMKL patients have an ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95452c63327502983a695359bdc7c12d
http://hdl.handle.net/10281/74463
http://hdl.handle.net/10281/74463
Autor:
Daniel Mertens, Peter Lichter, Christopher C. Oakes, Marc Zapatka, Ralf Kueppers, Amy S. Ruppert, Olga Bogatyrova, Lei Gu, Sandra D Koser, Thorsten Zenz, Andrius Serva, David Brocks, Stephan Stilgenbauer, Martina Przekopowitz, Daniel B. Lipka, Assenov Yassen, Marc Seifert, Christoph Plass, Hartmut Doehner, John C. Byrd
Publikováno v:
Clinical Cancer Research. 21:B25-B25
Knowledge of the cell-of-origin is essential for the full understanding of the causes of a malignant disease and for the rational design of targeted therapies. The B cell compartment is composed of a highly complex mixture of subtypes, each with dist