Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Hartmut, Kleinert"'
Autor:
Fabian Gather, Irmgard Ihrig-Biedert, Paul Kohlhas, Tamara Krutenko, Michael Peitz, Oliver Brüstle, Andrea Pautz, Hartmut Kleinert
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract Background NOS2 expression is mostly found in bacteria-exposed or cytokine-treated tissues and is mostly connected to innate immune reactions. There are three isoforms of NOS2 (NOS2-1 to -3). In RNA-seq data sets, analyzing inflammatory gene
Externí odkaz:
https://doaj.org/article/ed098a4fb932403ba31cdd861bb334d4
Autor:
Marin Kuntic, Ivana Kuntic, Roopesh Krishnankutty, Adrian Gericke, Matthias Oelze, Tristan Junglas, Maria Teresa Bayo Jimenez, Paul Stamm, Margaret Nandudu, Omar Hahad, Karin Keppeler, Steffen Daub, Ksenija Vujacic-Mirski, Sanela Rajlic, Lea Strohm, Henning Ubbens, Qi Tang, Subao Jiang, Yue Ruan, Kenneth G. Macleod, Sebastian Steven, Thomas Berkemeier, Ulrich Pöschl, Jos Lelieveld, Hartmut Kleinert, Alex von Kriegsheim, Andreas Daiber, Thomas Münzel
Publikováno v:
Redox Biology, Vol 59, Iss , Pp 102580- (2023)
Worldwide, up to 8.8 million excess deaths/year have been attributed to air pollution, mainly due to the exposure to fine particulate matter (PM). Traffic-related noise is an additional contributor to global mortality and morbidity. Both health risk
Externí odkaz:
https://doaj.org/article/a3483da95ed34c90ad76ad47abd956f7
Autor:
Jiong Hu, Marco Sisignano, Roman Brecht, Natarajan Perumal, Carlo Angioni, Iris-Sofia Bibli, Beate Fisslthaler, Hartmut Kleinert, Norbert Pfeiffer, Ingrid Fleming, Caroline Manicam
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Cytochrome P450 (CYP) signalling pathway has been shown to play a vital role in the vasoreactivity of wild type mouse ophthalmic artery. In this study, we determined the expression, vascular responses and potential mechanisms of the CYP-deri
Externí odkaz:
https://doaj.org/article/7c86336bfbe8447db07c79cc9df5eb60
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 26, Iss 5, Pp 85-101 (2021)
Nitric oxide synthases (NOS) are the major sources of nitric oxide (NO), a small bioactive molecule involved in the regulation of many cellular processes. One of the most prominent functions of NO is regulation of vasodilatation and thereby control o
Externí odkaz:
https://doaj.org/article/be936aac30f540ee9ca1fc311ff2cba4
Autor:
Kim-Alicia Palzer, Vanessa Bolduan, Rudolf Käfer, Hartmut Kleinert, Matthias Bros, Andrea Pautz
Publikováno v:
Cells, Vol 11, Iss 9, p 1482 (2022)
Post-transcriptional control of gene expression is one important mechanism that enables stringent and rapid modulation of cytokine, chemokines or growth factors expression, all relevant for immune or tumor cell function and communication. The RNA-bin
Externí odkaz:
https://doaj.org/article/b5c482d83c4d4f1498260adc6e97c547
Autor:
Lisa Schmidtke, Myriam Meineck, Sabrina Saurin, Svenja Otten, Fabian Gather, Katharina Schrick, Rudolf Käfer, Wilfried Roth, Hartmut Kleinert, Julia Weinmann-Menke, Andrea Pautz
Publikováno v:
Cells, Vol 10, Iss 11, p 3167 (2021)
KH-type splicing regulatory protein (KSRP) is an RNA-binding protein that promotes mRNA decay and thereby negatively regulates cytokine expression at the post-transcriptional level. Systemic lupus erythematosus (SLE) is an autoimmune disease characte
Externí odkaz:
https://doaj.org/article/da5060350d0742d68f0b00959c48e6d9
Autor:
Rudolf Käfer, Lisa Schmidtke, Katharina Schrick, Evelyn Montermann, Matthias Bros, Hartmut Kleinert, Andrea Pautz
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
The KH-type splicing regulatory protein (KSRP) is a RNA-binding protein, which regulates the stability of many mRNAs encoding immune-relevant proteins. As KSRP regulates innate immune responses, for instance by the modulation of type I interferon mRN
Externí odkaz:
https://doaj.org/article/d2459085f8d4409caaafef278e069e53
Autor:
Miroslava Kvandová, Sanela Rajlic, Paul Stamm, Isabella Schmal, Dominika Mihaliková, Marin Kuntic, Maria Teresa Bayo Jimenez, Omar Hahad, Marta Kollárová, Henning Ubbens, Lea Strohm, Katie Frenis, Georg Daniel Duerr, Marc Foretz, Benoit Viollet, Yue Ruan, Subao Jiang, Qi Tang, Hartmut Kleinert, Steffen Rapp, Adrian Gericke, Eberhard Schulz, Matthias Oelze, John F Keaney, Andreas Daiber, Swenja Kröller-Schön, Thomas Jansen, Thomas Münzel
Publikováno v:
European Journal of Preventive Cardiology.
Aims Environmental stressors such as traffic noise represent a global threat, accounting for 1.6 million healthy life years lost annually in Western Europe. Therefore, the noise-associated health side effects must be effectively prevented or mitigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d096410f2f507920163645eb05c006b
https://doi.org/10.1093/eurjpc/zwad075
https://doi.org/10.1093/eurjpc/zwad075
Autor:
Roland H. Stauber, Andreas du Bois, Wolf Mann, Hartmut Kleinert, Iris Hermanns, Valentina Nekljudova, Lars Hanker, Friedrich Kommoss, Annette Fisseler-Eckhoff, Andrea Schweitzer, Philipp Harter, Verena Fetz, Sibylle Loibl, Shirley K. Knauer, Knut Engels
Despite considerable success in the treatment of epithelial ovarian cancer (EOC), therapy resistance counteracts improvement of long-term survival. The dual role of survivin as an apoptosis inhibitor and mitotic regulator has been associated with dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d5f48ba462007eb2c769fc819b8a7f
https://doi.org/10.1158/0008-5472.c.6497738.v1
https://doi.org/10.1158/0008-5472.c.6497738.v1
Autor:
Roland H. Stauber, Andreas du Bois, Wolf Mann, Hartmut Kleinert, Iris Hermanns, Valentina Nekljudova, Lars Hanker, Friedrich Kommoss, Annette Fisseler-Eckhoff, Andrea Schweitzer, Philipp Harter, Verena Fetz, Sibylle Loibl, Shirley K. Knauer, Knut Engels
Supplementary Tables 1-3, Figure 1 from NO Signaling Confers Cytoprotectivity through the Survivin Network in Ovarian Carcinomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba0d5fb638d0176e9f59f9aff74a7856
https://doi.org/10.1158/0008-5472.22375220.v1
https://doi.org/10.1158/0008-5472.22375220.v1