Modelling the effectiveness of an isolation strategy for managing mpox outbreaks with variable infectiousness profiles.

Autor: Jeong YD; Interdisciplinary Biology Laboratory (iBLab), Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya, Japan.; Department of Mathematics, Pusan National University, Busan, 46241, South Korea., Hart WS; Interdisciplinary Biology Laboratory (iBLab), Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya, Japan.; Mathematical Institute, University of Oxford, Oxford, OX2 6GG, UK., Thompson RN; Mathematical Institute, University of Oxford, Oxford, OX2 6GG, UK., Ishikane M; Disease Control and Prevention Centre, National Centre for Global Health and Medicine, Tokyo, Japan., Nishiyama T; Interdisciplinary Biology Laboratory (iBLab), Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya, Japan., Park H; Interdisciplinary Biology Laboratory (iBLab), Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya, Japan., Iwamoto N; Disease Control and Prevention Centre, National Centre for Global Health and Medicine, Tokyo, Japan., Sakurai A; Disease Control and Prevention Centre, National Centre for Global Health and Medicine, Tokyo, Japan., Suzuki M; Disease Control and Prevention Centre, National Centre for Global Health and Medicine, Tokyo, Japan., Aihara K; International Research Center for Neurointelligence, The University of Tokyo Institutes for Advanced Study, The University of Tokyo, Tokyo, Japan., Watashi K; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan., Op de Coul E; Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., Ohmagari N; Disease Control and Prevention Centre, National Centre for Global Health and Medicine, Tokyo, Japan., Wallinga J; Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.; Department of Biomedical Data Sciences, Leiden University Medical Center (LUMC), Leiden, The Netherlands., Iwami S; Interdisciplinary Biology Laboratory (iBLab), Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya, Japan. iwami.iblab@bio.nagoya-u.ac.jp.; International Research Center for Neurointelligence, The University of Tokyo Institutes for Advanced Study, The University of Tokyo, Tokyo, Japan. iwami.iblab@bio.nagoya-u.ac.jp.; Institute of Mathematics for Industry, Kyushu University, Fukuoka, Japan. iwami.iblab@bio.nagoya-u.ac.jp.; Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University, Kyoto, Japan. iwami.iblab@bio.nagoya-u.ac.jp.; Interdisciplinary Theoretical and Mathematical Sciences Program (iTHEMS), RIKEN, Saitama, Japan. iwami.iblab@bio.nagoya-u.ac.jp.; NEXT-Ganken Program, Japanese Foundation for Cancer Research (JFCR), Tokyo, Japan. iwami.iblab@bio.nagoya-u.ac.jp.; Science Groove Inc., Fukuoka, Japan. iwami.iblab@bio.nagoya-u.ac.jp., Miura F; Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands. fuminari.miura@rivm.nl.; Center for Marine Environmental Studies (CMES), Ehime University, Matsuyama, Ehime, Japan. fuminari.miura@rivm.nl.

Publikováno v: Nature communications [Nat Commun] 2024 Aug 26; Vol. 15 (1), pp. 7112. Date of Electronic Publication: 2024 Aug 26.

A Histone Methylation-MAPK Signaling Axis Drives Durable Epithelial-Mesenchymal Transition in Hypoxic Pancreatic Cancer.

Autor: Brown BA; Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia., Myers PJ; Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia., Adair SJ; Department of Surgery, University of Virginia, Charlottesville, Virginia., Pitarresi JR; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Sah-Teli SK; Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, Oulu, Finland., Campbell LA; Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia., Hart WS; Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia., Barbeau MC; Biomedical Sciences, University of Virginia, Charlottesville, Virginia., Leong K; Engineering Science, University of Virginia, Charlottesville, Virginia., Seyler N; Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia., Kane W; Department of Surgery, University of Virginia, Charlottesville, Virginia., Lee KE; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan., Stelow E; Department of Pathology, University of Virginia, Charlottesville, Virginia., Jones M; Claude Moore Health Sciences Library, University of Virginia, Charlottesville, Virginia., Simon MC; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania.; Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, Pennsylvania., Koivunen P; Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, Oulu, Finland., Bauer TW; Department of Surgery, University of Virginia, Charlottesville, Virginia., Stanger BZ; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Lazzara MJ; Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia.; Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia.

Publikováno v: Cancer research [Cancer Res] 2024 Jun 04; Vol. 84 (11), pp. 1764-1780.

Divergent transcriptomic signatures from putative mesenchymal stimuli in glioblastoma cells.

Autor: Hart WS; Department of Chemical Engineering, University of Virginia, Charlottesville, VA, 22903, USA., Myers PJ; Department of Chemical Engineering, University of Virginia, Charlottesville, VA, 22903, USA., Purow BW; Department of Neurology, University of Virginia, Charlottesville, VA, 22903, USA., Lazzara MJ; Department of Chemical Engineering, University of Virginia, Charlottesville, VA, 22903, USA. mlazzara@virginia.edu.; Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, 22903, USA. mlazzara@virginia.edu.

Publikováno v: Cancer gene therapy [Cancer Gene Ther] 2024 Jun; Vol. 31 (6), pp. 851-860. Date of Electronic Publication: 2024 Feb 09.

Isolation may select for earlier and higher peak viral load but shorter duration in SARS-CoV-2 evolution.

Autor: Sunagawa J; Department of Advanced Transdisciplinary Sciences, Hokkaido University, Sapporo, Hokkaido, Japan., Park H; interdisciplinary Biology Laboratory (iBLab), Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya, Japan., Kim KS; interdisciplinary Biology Laboratory (iBLab), Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya, Japan.; Department of Scientific Computing, Pukyong National University, Busan, South Korea.; Department of Mathematics, Pusan National University, Busan, South Korea., Komorizono R; Laboratory of RNA Viruses, Department of Virus Research, Institute for Life and Medical Sciences (LiMe), Kyoto University, Kyoto, Japan., Choi S; interdisciplinary Biology Laboratory (iBLab), Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya, Japan.; Department of Mathematics, Pusan National University, Busan, South Korea., Ramirez Torres L; interdisciplinary Biology Laboratory (iBLab), Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya, Japan., Woo J; interdisciplinary Biology Laboratory (iBLab), Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya, Japan., Jeong YD; interdisciplinary Biology Laboratory (iBLab), Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya, Japan.; Department of Mathematics, Pusan National University, Busan, South Korea., Hart WS; Mathematical Institute, University of Oxford, Oxford, UK., Thompson RN; Mathematical Institute, University of Oxford, Oxford, UK.; Mathematics Institute, University of Warwick, Coventry, UK.; Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, University of Warwick, Coventry, UK., Aihara K; International Research Center for Neurointelligence, The University of Tokyo Institutes for Advanced Study, The University of Tokyo, Tokyo, Japan., Iwami S; interdisciplinary Biology Laboratory (iBLab), Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya, Japan. iwami.iblab@bio.nagoya-u.ac.jp.; Institute of Mathematics for Industry, Kyushu University, Fukuoka, Japan. iwami.iblab@bio.nagoya-u.ac.jp.; Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University, Kyoto, Japan. iwami.iblab@bio.nagoya-u.ac.jp.; Interdisciplinary Theoretical and Mathematical Sciences Program (iTHEMS), RIKEN, Saitama, Japan. iwami.iblab@bio.nagoya-u.ac.jp.; NEXT-Ganken Program, Japanese Foundation for Cancer Research (JFCR), Tokyo, Japan. iwami.iblab@bio.nagoya-u.ac.jp.; Science Groove Inc, Fukuoka, Japan. iwami.iblab@bio.nagoya-u.ac.jp., Yamaguchi R; Department of Advanced Transdisciplinary Sciences, Hokkaido University, Sapporo, Hokkaido, Japan. ryamaguchi@sci.hokudai.ac.jp.; Department of Zoology & Biodiversity Research Centre, University of British Columbia, Vancouver, BC, Canada. ryamaguchi@sci.hokudai.ac.jp.

Publikováno v: Nature communications [Nat Commun] 2023 Nov 21; Vol. 14 (1), pp. 7395. Date of Electronic Publication: 2023 Nov 21.

Understanding how transmembrane domains regulate interactions between human BST-2 and the SARS-CoV-2 accessory protein ORF7a.

Autor: Mann MM; Department of Chemical Engineering, University of Virginia, United States of America., Hsieh MK; Department of Chemical and Biomolecular Engineering, University of Maryland College Park, United States of America., Tang JD; Department of Chemical Engineering, University of Virginia, United States of America., Hart WS; Department of Chemical Engineering, University of Virginia, United States of America., Lazzara MJ; Department of Chemical Engineering, University of Virginia, United States of America., Klauda JB; Department of Chemical and Biomolecular Engineering, University of Maryland College Park, United States of America; Institute for Physical Science and Technology, Biophysics Program, University of Maryland College Park, United States of America. Electronic address: jbklauda@umd.edu., Berger BW; Department of Chemical Engineering, University of Virginia, United States of America; Department of Biomedical Engineering, University of Virginia, United States of America. Electronic address: bryan.berger@virginia.edu.

Publikováno v: Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2023 Aug; Vol. 1865 (6), pp. 184174. Date of Electronic Publication: 2023 May 19.