Structural Basis of Non-Latent Signaling by the Anti-Müllerian Hormone Procomplex.

Autor: Howard JA; Department of Pharmacology & Systems Physiology, University of Cincinnati, Cincinnati, OH, United States., Hok L; Department of Molecular & Cellular Biosciences, University of Cincinnati, Cincinnati, OH, United States., Cate RL; Department of Chemistry, Boston University, Boston, MA, United States., Sanford NJ; Department of Molecular & Cellular Biosciences, University of Cincinnati, Cincinnati, OH, United States., Hart KN; Department of Pharmacology & Systems Physiology, University of Cincinnati, Cincinnati, OH, United States., Leach EA; Department of Molecular & Cellular Biosciences, University of Cincinnati, Cincinnati, OH, United States., Bruening AS; Department of Molecular & Cellular Biosciences, University of Cincinnati, Cincinnati, OH, United States., Pépin D; Pediatric Surgical Research Laboratories, Massachusetts General Hospital, Department of Surgery, Harvard Medical School, Boston, MA, United States., Donahoe PK; Pediatric Surgical Research Laboratories, Massachusetts General Hospital, Department of Surgery, Harvard Medical School, Boston, MA, United States., Thompson TB; Department of Molecular & Cellular Biosciences, University of Cincinnati, Cincinnati, OH, United States.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Apr 01. Date of Electronic Publication: 2024 Apr 01.

Characterization of the molecular mechanisms that govern anti-Müllerian hormone synthesis and activity.

Autor: Stocker WA; Department of Physiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Howard JA; Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, Ohio, USA., Maskey S; Department of Physiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Luan H; Department of Physiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Harrison SG; Department of Physiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Hart KN; Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, Ohio, USA., Hok L; Department of Molecular and Cellular Biosciences, University of Cincinnati, Cincinnati, Ohio, USA., Thompson TB; Department of Molecular and Cellular Biosciences, University of Cincinnati, Cincinnati, Ohio, USA., Walton KL; Department of Physiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.; School of Biomedical Sciences, The University of Queensland, Brisbane, Queensland, Australia., Harrison CA; Department of Physiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Jan; Vol. 38 (1), pp. e23377.

Structure of AMH bound to AMHR2 provides insight into a unique signaling pair in the TGF-β family.

Autor: Hart KN; Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH 45267.; Department of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati, Cincinnati, OH 45267., Stocker WA; Department of Physiology, Monash University, Clayton, VIC 3800, Australia.; Department of Chemistry and Biotechnology, Swinburne University of Technology, Hawthorn, VIC 3122, Australia., Nagykery NG; Pediatric Surgical Research Laboratories, Massachusetts General Hospital, Boston, MA 02114.; Department of Surgery, Harvard Medical School, Boston, MA 02115., Walton KL; Department of Physiology, Monash University, Clayton, VIC 3800, Australia., Harrison CA; Department of Physiology, Monash University, Clayton, VIC 3800, Australia., Donahoe PK; Pediatric Surgical Research Laboratories, Massachusetts General Hospital, Boston, MA 02114.; Department of Surgery, Harvard Medical School, Boston, MA 02115., Pépin D; Pediatric Surgical Research Laboratories, Massachusetts General Hospital, Boston, MA 02114.; Department of Surgery, Harvard Medical School, Boston, MA 02115., Thompson TB; Department of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati, Cincinnati, OH 45267; tom.thompson@uc.edu.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jun 29; Vol. 118 (26).

Mutational Analysis of the Putative Anti-Müllerian Hormone (AMH) Binding Interface on its Type II Receptor, AMHR2.

Autor: Hart KN; Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, OH, USA.; Department of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati, Cincinnati, OH, USA., Pépin D; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Pediatric Surgical Research Laboratories, Massachusetts General Hospital, Boston, MA, USA., Czepnik M; Department of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati, Cincinnati, OH, USA., Donahoe PK; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Pediatric Surgical Research Laboratories, Massachusetts General Hospital, Boston, MA, USA., Thompson TB; Department of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati, Cincinnati, OH, USA.

Publikováno v: Endocrinology [Endocrinology] 2020 Jul 01; Vol. 161 (7).