Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hart, L.M. 't"'
Autor:
Wang, W.Y., Luo, J., Dijk, K.W. van, Hagg, S., Grassmann, F., Hart, L.M. 't, Heemst, D. van, Noordam, R.
Publikováno v:
Diabetologia, 65, 1676-1686. SPRINGER
Aims/hypothesis Mitochondrial dysfunction, which can be approximated by blood mitochondrial DNA copy number (mtDNA-CN), has been implicated in the pathogenesis of type 2 diabetes mellitus. Thus far, however, insights from prospective cohort studies a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26510fba84bb47bc88ce9ea35ddeb72
https://hdl.handle.net/1887/3562831
https://hdl.handle.net/1887/3562831
Autor:
Dawed, A.Y., Yee, S.W., Zhou, K.X., Leeuwen, N. van, Zhang, Y.F., Siddiqui, M.K., Etheridge, A., Innocenti, F., Xu, F., Li, J.H., Beulens, J.W., Heijden, A.A. van der, Slieker, R.C., Chang, Y.C., Mercader, J.M., Kaur, V., Witte, J.S., Lee, M.T.M., Kamatani, Y., Momozawa, Y., Kubo, M., Palmer, C.N.A., Florez, J.C., Hedderson, M.M., Hart, L.M. 't, Giacomini, K.M., Pearson, E.R., MetGen Plus DIRECT Consortium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3e64b97fd14541ae74ac175ab356ddf6
https://doi.org/10.2337/dci21-0066
https://doi.org/10.2337/dci21-0066
Autor:
Hagenbeek, F.A., Pool, R., Dongen, J. van, Draisma, H.H.M., Hottenga, J.J., Willemsen, G., Abdellaoui, A., Fedko, I.O., Braber, A. den, Visser, P.J., Geus, E.J.C.N. de, Dijk, K.W. van, Verhoeven, A., Suchiman, H.E., Beekman, M., Slagboom, P.E., Duijn, C.M. van, Harms, A.C., Hankemeier, T., Bartels, M., Nivard, M.G., Boomsma, D.I., Wolf, J.J.H.B., Cats, D., Amin, N., Beulens, J.W., Bom, J.A. van der, Bomer, N., Demirkan, A., Hilten, J.A. van, Meessen, J.M.T.A., Moed, M.H., Fu, J., Onderwater, G.L.J., Rutters, F., So-Osman, C., Flier, W.M. van der, Heijden, A.A.W.A. van der, Spek, A. van der, Asselbergs, F.W., Boersma, E., Elders, P.M., Geleijnse, J.M., Ikram, M.A., Kloppenburg, M., Meulenbelt, I., Mooijaart, S.P., Nelissen, R.G.H.H., Netea, M.G., Penninx, B.W.J.H., Stehouwer, C.D.A., Teunissen, C.E., Terwindt, G.M., Hart, L.M. 't, Maagdenberg, A.M.J.M. van den, Harst, P. van der, Horst, I.C.C. van der, Kallen, C.J.H. van der, Greevenbroek, M.M.J. van, Spil, W.E. van, Wijmenga, C., Zwinderman, A.H., Zhernikova, A., Jukema, J.W., Mei, H., Slofstra, M., Swertz, M., Akker, E.B. van den, Deelen, J., Reinders, M.J.T., BBMRI Metabolomics Consortium
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications, 11(1):39. Nature Publishing Group
Nature Communications
Nature Communications, 11(1)
Nature Communications, 11, 1
Nature Communications, 11(1). NATURE PUBLISHING GROUP
Nature Communications 11 (2020) 1
Nature communications, 11(1):39. Nature Publishing Group
BBMRI Metabolomics Consortium 2020, ' Heritability estimates for 361 blood metabolites across 40 genome-wide association studies ', Nature Communications, vol. 11, no. 1, 39 . https://doi.org/10.1038/s41467-019-13770-6
Hagenbeek, F A, Pool, R, van Dongen, J, Draisma, H H M, Jan Hottenga, J, Willemsen, G, Abdellaoui, A, Fedko, I O, den Braber, A, de Geus, E J C N, Bartels, M, Nivard, M G, Boomsma, D I & BBMRI Metabolomics Consortium 2020, ' Heritability estimates for 361 blood metabolites across 40 genome-wide association studies ', Nature Communications, vol. 11, no. 1, 39, pp. 1-11 . https://doi.org/10.1038/s41467-019-13770-6
Nature Communications, 11
Nature Communications, 11(1):39, 1-11. Nature Publishing Group
Nature Communications, 11(1):39. Nature Publishing Group
Nature Communications
Nature Communications, 11(1)
Nature Communications, 11, 1
Nature Communications, 11(1). NATURE PUBLISHING GROUP
Nature Communications 11 (2020) 1
Nature communications, 11(1):39. Nature Publishing Group
BBMRI Metabolomics Consortium 2020, ' Heritability estimates for 361 blood metabolites across 40 genome-wide association studies ', Nature Communications, vol. 11, no. 1, 39 . https://doi.org/10.1038/s41467-019-13770-6
Hagenbeek, F A, Pool, R, van Dongen, J, Draisma, H H M, Jan Hottenga, J, Willemsen, G, Abdellaoui, A, Fedko, I O, den Braber, A, de Geus, E J C N, Bartels, M, Nivard, M G, Boomsma, D I & BBMRI Metabolomics Consortium 2020, ' Heritability estimates for 361 blood metabolites across 40 genome-wide association studies ', Nature Communications, vol. 11, no. 1, 39, pp. 1-11 . https://doi.org/10.1038/s41467-019-13770-6
Nature Communications, 11
Nature Communications, 11(1):39, 1-11. Nature Publishing Group
Metabolomics examines the small molecules involved in cellular metabolism. Approximately 50% of total phenotypic differences in metabolite levels is due to genetic variance, but heritability estimates differ across metabolite classes. We perform a re
Autor:
Dawed, A.Y., Zhou, K.X., Leeuwen, N. van, Mahajan, A., Robertson, N., Koivula, R., Elders, P.J.M., Rauh, S.P., Jones, A.G., Holl, R.W., Stingl, J.C., Franks, P.W., McCarthy, M.I., Hart, L.M. 't, Pearson, E.R., IMI DIRECT Consortium
OBJECTIVEGastrointestinal adverse effects occur in 20-30% of patients with metformin-treated type 2 diabetes, leading to premature discontinuation in 5-10% of the cases. Gastrointestinal intolerance may reflect localized high concentrations of metfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______202::4cd9ad0aac30d04c58ef5baa87c5076c
https://hdl.handle.net/1887/3630742
https://hdl.handle.net/1887/3630742
Autor:
Simons, N., Bijnen, M., Wouters, K.A.M., Rensen, S.S., Beulens, J.W.J., Dekker, J.M., van Greevenbroek, M.M.J., Nijpels, G., Hart, L.M. ’t, van der Kallen, C.J.H., Schaper, N.C., Schalkwijk, C.G., Stehouwer, C.D.A., Brouwers, M.C.G.J.
Publikováno v:
In Atherosclerosis August 2019 287:e95-e96
Autor:
Raalte, D.H. van, Leeuwen, N. van, Simonis-Bik, A.M., Nijpels, G., Haeften, T.W. van, Schafer, S.A., Boomsma, D.I., Kramer, M.H.H., Heine, R.J., Maassen, J.A., Staiger, H., Machicao, F., Haring, H.U., Slagboom, P.E., Willemsen, G., Geus, E.J. de, Dekker, J.M., Fritsche, A., Eekhoff, E.M., Diamant, M., Hart, L.M. 't
Publikováno v:
van Raalte, D H, van Leeuwen, N, Bik-Simonis, A M C, Nijpels, G, van Haeften, T W, Schafer, S A, Boomsma, D I, Kramer, M H H, Heine, R J, Maassen, J A, Staiger, H, Machicao, F, Häring, H U, Slagboom, P E, Willemsen, G, de Geus, E J C, Dekker, J M, Fritsche, A, Eekhoff, E M W, Diamant, M & Hart, L M 2012, ' Glucocorticoid receptor gene polymorphisms are associated with reduced first-phase glucose-stimulated insulin secretion and disposition index in women, but not in men ', Diabetic Medicine, vol. 29, no. 8, pp. e211-e216 . https://doi.org/10.1111/j.1464-5491.2012.03690.x
Diabetic Medicine, 29(8), e211-e216. Wiley-Blackwell
Diabetic Medicine, 29(8), e211-e216. Wiley-Blackwell Publishing
Diabetic Medicine, 29(8), e211-e216. Wiley-Blackwell
Diabetic Medicine, 29(8), e211-e216. Wiley-Blackwell Publishing
Glucocorticoids are efficacious anti-inflammatory agents, but, in susceptible individuals, these drugs may induce glucose intolerance and diabetes by affecting β-cell function and insulin sensitivity. We assessed whether polymorphisms in the glucoco
Autor:
Lapauw, B., Ouwens, M., Hart, L.M. 't, Wuyts, B., Holst, J.J., T'Sjoen, G., Kaufman, J.M., Ruige, J.B.
Publikováno v:
Diabetes Care, 33(8), 1831-1833
OBJECTIVE- To evaluate metabolic effects of sex steroids in nonfasting and fasting conditions, independent from changes in body composition. RESEARCH DESIGN AND METHODS- A randomized clinical trial was performed to create contrasting sex steroid leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d8668ea0468f06b006bb44df6e9f61a3
https://hdl.handle.net/1887/110136
https://hdl.handle.net/1887/110136
Autor:
Monraats, P.S., Pires, N.M.M., Schepers, A., Agema, W.R.P., Boesten, L.S.M., Vries, M.R. de, Zwinderman, A.H., Maat, M.P.M. de, Doevendans, P.A.F.M., Winter, R.J. de, Tio, R.A., Waltenberger, J., Hart, L.M. 't, Frants, R.R., Quax, P.H.A., Vlijmen, B.J.M. van, Havekes, L.M., Laarse, A. van der, Wall, E.E. van der, Jukema, J.W.
Publikováno v:
FASEB Journal, 14, 19, 1998-2004
Genetic factors appear to be important in the restenotic process after percutaneous coronary intervention (PCI), as well as in inflammation, a pivotal factor in restenosis. TNFα, a key regulator of inflammatory responses, may exert critical influenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6d6f7f2580c2d1d4b2361411733596e6
http://resolver.tudelft.nl/uuid:11506bee-65f4-4c8d-9f02-23c7c8aeb89b
http://resolver.tudelft.nl/uuid:11506bee-65f4-4c8d-9f02-23c7c8aeb89b
Autor:
Janssen, J.J.M., Maassen, J.A., Woude, F. van der, Lemmink, H.H., Ouweland, J.M.W. van den, Hart, L.M. 't, Smeets, H.J.M., Bruyn, J.A., Lemkes, H.H.D.J.
Publikováno v:
Journal of the American Society of Nephrology, 8, 1118-1124
Journal of the American Society of Nephrology, 8, pp. 1118-1124
Journal of the American Society of Nephrology, 8, pp. 1118-1124
Item does not contain fulltext 7 p.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::fcab963cecdf0a6e2d9610c47ad97d42
http://hdl.handle.net/2066/157050
http://hdl.handle.net/2066/157050
Autor:
Jansen, J.J.M., Maassen, J.A., Woude, F. van der, Lemmink, H.H., Ouweland, J.M.W. van den, Hart, L.M. 't, Smeets, H.J.M., Bruyn, J.A., Lemkes, H.H.P.J.
Publikováno v:
Journal of the American Society of Nephrology, 8, 1118-1124
Journal of the American Society of Nephrology, 8, 7, pp. 1118-1124
Journal of the American Society of Nephrology, 8, 7, pp. 1118-1124
Contains fulltext : 24462___.PDF (Publisher’s version ) (Open Access)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::60219630817efb654eb10c783981b793
http://hdl.handle.net/2066/24462
http://hdl.handle.net/2066/24462