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pro vyhledávání: '"Harshfield AT"'
Autor:
Cecilia Castro, Eric L. Harshfield, Adam S. Butterworth, Angela M. Wood, Albert Koulman, Julian L. Griffin
Publikováno v:
Data in Brief, Vol 57, Iss , Pp 110925- (2024)
Understanding the cause of coronary heart diseases relies on the analysis of data from a range of techniques on an epidemiological scale. Lipidomics, the identification and quantification of lipid species in a system, is an omic approach increasingly
Externí odkaz:
https://doaj.org/article/8944e214c8564666b17786287c5bcf45
Publikováno v:
Quality Progress. Nov2024, Vol. 57 Issue 11, p30-37. 8p.
Autor:
Rui Li, Eric Harshfield, Steven Bell, Michael Burkhart, Anil Tuladhar, Saima Hilal, Daniel Tozer, Francesca Chappell, Stephen Makin, Jessica Lo, Joanna Wardlaw, Frank-Erik de Leeuw, Christopher Chen, Zoe Kourtzi, Hugh Markus
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100235- (2024)
Introduction: Cerebral small vessel disease (SVD) contributes to 45% of dementia cases worldwide. Only a minority of SVD patients develop dementia, yet we lack a reliable model for predicting incident dementia in SVD. Most attempts to date have relie
Externí odkaz:
https://doaj.org/article/258f4cb4ab2146e6af7cf5085e948f47
Autor:
Robin Brown, Daniel Tozer, Laurence Loubiere, Eric Harshfield, Young Hong, Tim Fryer, Guy Williams, Martin Graves, Franklin Aigbirhio, John O'Brien, Hugh Markus
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100316- (2024)
Introduction: Cerebral small vessel disease (SVD) is a major cause of cognitive impairment and stroke. Neuroinflammation and blood-brain barrier (BBB) leakage may play a role in pathogenesis, but no definitive causal link has been established. In a r
Externí odkaz:
https://doaj.org/article/3719b23f3e3442ee92ce6fc9a1858647
Autor:
Jennifer Carlisle Michel, Margaret M B Grivette, Amber T Harshfield, Lisa Huynh, Ava P Komons, Bradley Loomis, Kaitlan McKinnis, Brennen T Miller, Ethan Q Nguyen, Tiffany W Huang, Sophia Lauf, Elias S Michel, Mia E Michel, Jane S Kissinger, Audrey J Marsh, William E Crow, Lila E Kaye, Abagael M Lasseigne, Rachel M Lukowicz-Bedford, Dylan R Farnsworth, E Anne Martin, Adam C Miller
Publikováno v:
PLoS Genetics, Vol 19, Iss 11, p e1011045 (2023)
Electrical synapses are neuronal gap junction (GJ) channels associated with a macromolecular complex called the electrical synapse density (ESD), which regulates development and dynamically modifies electrical transmission. However, the proteomic mak
Externí odkaz:
https://doaj.org/article/d248fc86adaa456a9e2ad5a07340bcaf
Autor:
Li, Rui, Harshfield, Eric L., Bell, Steven, Burkhart, Michael, Tuladhar, Anil M., Hilal, Saima, Tozer, Daniel J., Chappell, Francesca M., Makin, Stephen D.J., Lo, Jessica W., Wardlaw, Joanna M., de Leeuw, Frank-Erik, Chen, Christopher, Kourtzi, Zoe, Markus, Hugh S.
Publikováno v:
In Cerebral Circulation - Cognition and Behavior 2023 5
Publikováno v:
BMC Cardiovascular Disorders, Vol 23, Iss 1, Pp 1-3 (2023)
Abstract Cerebrovascular disorders pose a global health concern. Advances in basic and clinical research, including induced pluripotent stem cell models and multi-omic approaches, have improved our understanding and management of these disorders. How
Externí odkaz:
https://doaj.org/article/c4ad12ae5c66414fa3fd0fe2d63451a8
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 14 (2023)
Background White matter hyperintensities (WMHs) are a major risk factor for stroke and dementia, but their pathogenesis is incompletely understood. It has been debated how much risk is accounted for by conventional cardiovascular risk factors (CVRFs)
Externí odkaz:
https://doaj.org/article/ba983636fb2f42e8adab121567a067ca
Akademický článek
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Autor:
Rui Li, Eric L. Harshfield, Steven Bell, Michael Burkhart, Anil M. Tuladhar, Saima Hilal, Daniel J. Tozer, Francesca M. Chappell, Stephen D.J. Makin, Jessica W. Lo, Joanna M. Wardlaw, Frank-Erik de Leeuw, Christopher Chen, Zoe Kourtzi, Hugh S. Markus
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 5, Iss , Pp 100179- (2023)
Background: Cerebral small vessel disease (SVD) contributes to 45% of dementia cases worldwide, yet we lack a reliable model for predicting dementia in SVD. Past attempts largely relied on traditional statistical approaches. Here, we investigated whe
Externí odkaz:
https://doaj.org/article/f6fd45ab5ab94d0f8ed7bd9079eaaa94