Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Harshad, Ingle"'
Autor:
Jacob A Van Winkle, Stefan T Peterson, Elizabeth A Kennedy, Michael J Wheadon, Harshad Ingle, Chandni Desai, Rachel Rodgers, David A Constant, Austin P Wright, Lena Li, Maxim N Artyomov, Sanghyun Lee, Megan T Baldridge, Timothy J Nice
Publikováno v:
eLife, Vol 11 (2022)
Interferon-lambda (IFN-λ) protects intestinal epithelial cells (IECs) from enteric viruses by inducing expression of antiviral IFN-stimulated genes (ISGs). Here, we find that bacterial microbiota stimulate a homeostatic ISG signature in the intestin
Externí odkaz:
https://doaj.org/article/49f905267f26475caccf534d5cf8c0dd
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
MicroRNAs are short non-coding RNAs that play a crucial role in the regulation of gene expression during cellular processes. The host-encoded miRNAs are known to modulate the antiviral defense during viral infection. In the last decade, multiple DNA
Externí odkaz:
https://doaj.org/article/01e66cafeaeb463e9fe60f77f851ad4d
Publikováno v:
Annual Review of Virology. 10
The mammalian gastrointestinal tract (GIT) hosts a diverse and highly active microbiota composed of bacteria, eukaryotes, archaea, and viruses. Studies of the GIT microbiota date back more than a century, although modern techniques, including mouse m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e393ec48da839bb20013020120e6cfd
https://doi.org/10.1146/annurev-virology-111821-115754
https://doi.org/10.1146/annurev-virology-111821-115754
Publikováno v:
Viruses, Vol 12, Iss 8, p 904 (2020)
Enteric viral co-infections, infections involving more than one virus, have been reported for a diverse group of etiological agents, including rotavirus, norovirus, astrovirus, adenovirus, and enteroviruses. These pathogens are causative agents for a
Externí odkaz:
https://doaj.org/article/73e9712501f94f00a4126bf4d40a7620
Autor:
Gowri Kalugotla, Harshad Ingle, Belgacem Mihi, Megan T. Baldridge, Misty Good, Michael S. Diamond, Rodney D. Newberry, Keely G. McDonald, Yuhao Li, Pritesh Desai, Sanghyun Lee, Ebrahim Hassan, Jana Gawron, Elizabeth A. Kennedy, Heyde Makimaa
Publikováno v:
Mucosal immunology
Although they globally cause viral gastroenteritis in children, astroviruses are understudied due to the lack of well-defined animal models. While murine astroviruses (muAstVs) chronically infect immunodeficient mice, a culture system and understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400acaf2d9ba4a9f12c805d983885dda
http://europepmc.org/articles/PMC8085034
http://europepmc.org/articles/PMC8085034
Autor:
Jacob A Van Winkle, Stefan T Peterson, Elizabeth A Kennedy, Michael J Wheadon, Harshad Ingle, Chandni Desai, Rachel Rodgers, David A Constant, Austin P Wright, Lena Li, Maxim N Artyomov, Sanghyun Lee, Megan T Baldridge, Timothy J Nice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd9916b5ce3b6d8271857be63c9806d3
https://doi.org/10.7554/elife.74072.sa2
https://doi.org/10.7554/elife.74072.sa2
Publikováno v:
Viruses, Vol 10, Iss 1, p 46 (2018)
Interferons (IFNs) are key host cytokines in the innate immune response to viral infection, and recent work has identified unique roles for IFN subtypes in regulating different aspects of infection. Currently emerging is a common theme that type III
Externí odkaz:
https://doaj.org/article/0194be72b0a647e8b319048c9f9706f8
Autor:
Sanghyun, Lee, Gowri, Kalugotla, Harshad, Ingle, Rachel, Rodgers, Chunyan, Wu, Yating, Wang, Yuhao, Li, Xia, Yang, Jin, Zhang, Nicolette R, Borella, Hongju, Deng, Lindsay, Droit, Ryan, Hill, Stefan T, Peterson, Chandni, Desai, Dylan, Lawrence, Qun, Lu, Megan T, Baldridge
Publikováno v:
Autophagy. 18(5)
Mutations in the macroautophagy/autophagy gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e2c5ff68bcf71aff36b57a155d2d21e
https://pubmed.ncbi.nlm.nih.gov/34520306
https://pubmed.ncbi.nlm.nih.gov/34520306
Autor:
Jacob A. Van Winkle, Stefan T. Peterson, Elizabeth A. Kennedy, Michael J. Wheadon, Harshad Ingle, Chandni Desai, Rachel Rodgers, David A. Constant, Austin P. Wright, Lena Li, Maxim Artyomov, Sanghyun Lee, Megan T. Baldridge, Timothy J. Nice
Interferon-lambda (IFN-λ) protects intestinal epithelial cells (IECs) from enteric viruses by inducing expression of antiviral IFN-stimulated genes (ISGs). Here, we find that bacterial microbiota stimulate a homeostatic ISG signature in the intestin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac8f1b85a8ecc1ca656b1f26a44464d5
https://doi.org/10.1101/2021.06.02.446828
https://doi.org/10.1101/2021.06.02.446828
Autor:
Rachel Rodgers, Harshad Ingle, Gowri Kalugotla, Xia Yang, Qun Lu, Chandni Desai, Sanghyun Lee, Nicolette R. Borella, Lindsay Droit, Ryan Hill, Megan T. Baldridge, Stefan T. Peterson, Chunyan Wu, Yuhao Li, Hongju Deng, Dylan Lawrence, Ya-Ting Wang, Jin Zhang
Mutations in the macroautophagy/autophagy gene EPG5 are responsible for Vici syndrome, a human genetic disease characterized by combined immunodeficiency. Previously, we found that epg5−/- mice exhibit hyperinflammation in the lungs mediated by IL1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7003222bb447a5961904bad5671c8d