Technology Adoption Model-Based Comparison of Clinical Trial Software

Autor: Hossain Shahriar, Evbusogie Sogbesan, Lorna Migiro, Temitope Balogun, Sweta Sneha, Harsha Rajasimha, Arleen Joy Patinga, Masrura Tasnim

Publikováno v: International Journal of Applied Research on Public Health Management. 8:1-24

Clinical research management systems are mainly used by both pharmaceutical companies and biotechnology companies to manage the clinical trial process from start to finish. Due to the very nature and complexity of the clinical research process, havin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e2c05df106e2e8ff4fc74873a34226f6
https://doi.org/10.4018/ijarphm.315803

Developing Rods Transplanted into the Degenerating Retina of Crx-Knockout Mice Exhibit Neural Activity Similar to Native Photoreceptors

Autor: Kohei Homma, Satoshi Okamoto, Wei Li, Shan Chen, Michiko Mandai, Harsha Rajasimha, Masayo Takahashi, Tiziana Cogliati, Norimoto Gotoh, Yi Sheng Chang, Anand Swaroop

Publikováno v: Stem Cells. 31:1149-1159

Replacement of dysfunctional or dying photoreceptors offers a promising approach for retinal neurodegenerative diseases, including age-related macular degeneration and retinitis pigmentosa. Several studies have demonstrated the integration and differ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2504884296c49cd6556c7c83fd68f46
https://doi.org/10.1002/stem.1372

Toward more transparent and reproducible omics studies through a common metadata checklist and data publications

Autor: Matthew E. Monroe, Kenneth Verheggen, Brynn H. Voy, Allison Heath, Gordon A. Anderson, Alexander Kel, Dmitrij Frishman, Srikanth Rapole, Larry Smarr, Imre Janko, Gilbert S. Omenn, Louise Warnich, Natali Kolker, Vural Ozdemir, Ancha Baranova, Elizabeth Stewart, Lihua Jiang, Sanjeeva Srivastava, John Choiniere, Lennart Martens, Wu-chun Feng, Isaac S. Kohane, Geoffrey C. Fox, Harsha Rajasimha, Preveen Ramamoorthy, Jean-Claude Marshall, Jerry Sheehan, Nathaniel Anderson, Stefano Toppo, Eugene Kolker, William S. Hancock, Shawn R. Campagna, Santosh Noronha, Lynnette R. Ferguson, Paola Masuzzo, Charles V. Smith, Alexey I. Nesvizhskii, Robert L. Grossman, Gregory Yandl, Rui Chen, Joseph W. Kemnitz, Elaine Lee, Stephen P. Dearth, Michael Snyder, Elizabeth Montague, Roger Higdon, Andrey Lisitsa, Weizhong Li, Sean D. Mooney, Adrián LLerena, Courtney MacNealy-Koch, Mara H. Hutz, Doron Lancet, George I. Mias, Todd M. Smith, Sanjay Joshi, Amanda L. May, Sukru Aynacioglu, Steven W. Wilhelm, Larissa Stanberry, Peter Uetz

Publikováno v: Omics : a journal of integrative biology. 18(1)

Biological processes are fundamentally driven by complex interactions between biomolecules. Integrated high-throughput omics studies enable multifaceted views of cells, organisms, or their communities. With the advent of new post-genomics technologie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302b45c041ce1d70ff3a2d3d53f8f37c
https://pubmed.ncbi.nlm.nih.gov/24456465

Exome Sequencing: Capture and Sequencing of All Human Coding Regions for Disease Gene Discovery

Autor: Harsha Rajasimha, Anand Swaroop, Matthew Brooks, Rinki Ratna Priya

Publikováno v: Retinal Development ISBN: 9781617798474

In humans, protein-coding exons constitute 1.5-1.7% of the human genome. Targeted sequencing of all coding exons is termed as exome sequencing. This method enriches for coding sequences at a genome-wide scale from 3 μg of DNA in a hybridization capt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1833a39e830614ae8d344627b768078f
https://doi.org/10.1007/978-1-61779-848-1_24

The BioPAX community standard for pathway data sharing

Autor: Margot Sunshine, Frank Schacherer, Nigam H. Shah, Akhilesh Pandey, Harsha Rajasimha, Andrew Finney, Rebecca Tang, Martijn P. van Iersel, Kumaran Kandasamy, Kei-Hoi Cheung, Martina Kutmon, Geeta Joshi-Tope, Matthias Samwald, Dean Ravenscroft, Mustafa H Syed, Vincent Schächter, Michael L. Blinov, Chris Sander, Liya Ren, Guanming Wu, Christian Lemer, Zhenjun Hu, Peter Hornbeck, Andrey Rzhetsky, Nicolas Le Novère, Emek Demir, Shiva Krupa, Michelle Whirl-Carrillo, Ken Fukuda, Alejandra López-Fuentes, Michael P. Cary, Erik Brauner, David Merberg, Julie Leonard, Imran Shah, David W. Kane, Alexander R. Pico, Shannon K. McWeeney, Michael Hucka, Peter D. Karp, Nadia Anwar, Andrea Splendiani, Peter D'Eustachio, Olivier Hubaut, Ugur Dogrusoz, Julio Collado-Vides, Gary D. Bader, Jeremy Zucker, Carl F. Schaefer, Keith Allen, Kam D. Dahlquist, Oliver Reubenacker, Paul Thomas, Mirit I. Aladjem, Victoria Petri, Verónica Jiménez-Jacinto, Igor Rodchenkov, Edgar Wingender, Gopal R. Gopinath, Imre Vastrik, Stan Letovksy, Susumu Goto, Ryan Whaley, Frank Gibbons, Natalia Maltsev, Özgün Babur, Ranjani Ramakrishnan, Robin Haw, Elgar Pichler, Burk Braun, Sylva L. Donaldson, Suzanne M. Paley, Huaiyu Mi, Sarala M. Wimalaratne, Elizabeth M. Glass, Sasha Tkachev, Irma Martínez-Flores, Augustin Luna, Joanne S. Luciano, Debbie Marks, Marc Gillespie, Michael Honig, Ewan Birney, Dan Corwin, Bruno S. Sobral, Kenneth H. Buetow, Li Gong, Eric K. Neumann, Robert N. Goldberg, Peter Murray-Rust

Publikováno v: Nature biotechnology
Nature Biotechnology
Nature Biotechnology, 28(9), 935-42. Nature Publishing Group

BioPAX (Biological Pathway Exchange) is a standard language to represent biological pathways at the molecular and cellular level. Its major use is to facilitate the exchange of pathway data (http://www.biopax.org). Pathway data captures our understan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d104cbe5aa6621a4df6eefcda72f4a5
https://resolver.caltech.edu/CaltechAUTHORS:20100929-111828470