Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Harsha Mahabaleshwar"'
Autor:
Jiajia Ma, Claire A Scott, Ying Na Ho, Harsha Mahabaleshwar, Katherine S Marsay, Changqing Zhang, Christopher KJ Teow, Ser Sue Ng, Weibin Zhang, Vinay Tergaonkar, Lynda J Partridge, Sudipto Roy, Enrique Amaya, Tom J Carney
Publikováno v:
eLife, Vol 10 (2021)
Epithelial tissues are primed to respond to insults by activating epithelial cell motility and rapid inflammation. Such responses are also elicited upon overexpression of the membrane-bound protease, Matriptase, or mutation of its inhibitor, Hai1. Un
Externí odkaz:
https://doaj.org/article/380d55289a8f47f281a3eaefddfb6c5e
Autor:
Katherine S Marsay, Sarah Greaves, Harsha Mahabaleshwar, Charmaine Min Ho, Henry Roehl, Peter N Monk, Tom J Carney, Lynda J Partridge
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0260372 (2021)
Collective cell migration is essential for embryonic development and homeostatic processes. During zebrafish development, the posterior lateral line primordium (pLLP) navigates along the embryo flank by collective cell migration. The chemokine recept
Externí odkaz:
https://doaj.org/article/5bd127ea37cd444abb64e1112e5a5886
Autor:
Ulrike Naumann, Elisabetta Cameroni, Monika Pruenster, Harsha Mahabaleshwar, Erez Raz, Hans-Günter Zerwes, Antal Rot, Marcus Thelen
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9175 (2010)
BACKGROUND:CXCR7 (RDC1), the recently discovered second receptor for CXCL12, is phylogenetically closely related to chemokine receptors, but fails to couple to G-proteins and to induce typical chemokine receptor mediated cellular responses. The funct
Externí odkaz:
https://doaj.org/article/670aaf6339124a9a864e47a634a83cb5
Autor:
Keh-Weei Tzung, Robert L. Lalonde, Karin D. Prummel, Harsha Mahabaleshwar, Hannah R. Moran, Jan Stundl, Amanda N. Cass, Yao Le, Robert Lea, Karel Dorey, Monika J. Tomecka, Changqing Zhang, Eline C. Brombacher, William T. White, Henry H. Roehl, Frank J. Tulenko, Christoph Winkler, Peter D. Currie, Enrique Amaya, Marcus C. Davis, Marianne E. Bronner, Christian Mosimann, Tom J. Carney
Publikováno v:
Nature.
The development of paired appendages was a key innovation during evolution and facilitated the aquatic to terrestrial transition of vertebrates. Largely derived from the lateral plate mesoderm (LPM), one hypothesis for the evolution of paired fins in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467e218457f50e8ddc9901c2866d6cfb
https://doi.org/10.1038/s41586-023-06100-w
https://doi.org/10.1038/s41586-023-06100-w
During development and regeneration, cells migrate to specific locations within growing tissues. These cells can respond to both biochemical signals and mechanical cues, resulting in directed migration. Such migration is often highly stereotypic. Yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eee45a2d3b2e17b33c667bb4102723e6
https://doi.org/10.1101/2022.05.13.491825
https://doi.org/10.1101/2022.05.13.491825
Autor:
Harsha Mahabaleshwar, PV Asharani, Tricia Yi Loo, Shze Yung Koh, Melissa R Pitman, Samuel Kwok, Jiajia Ma, Bo Hu, Fang Lin, Xue Li Lok, Stuart M Pitson, Timothy E Saunders, Tom J Carney
Publikováno v:
EMBO Rep
Immigration of mesenchymal cells into the growing fin and limb buds drives distal outgrowth, with subsequent tensile forces between these cells essential for fin and limb morphogenesis. Morphogens derived from the apical domain of the fin, orientate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da3d15f5b3c9f81e0c200f2e8c56e53
https://pubmed.ncbi.nlm.nih.gov/35679135
https://pubmed.ncbi.nlm.nih.gov/35679135
Autor:
Harsha Mahabaleshwar, P.V. Asharani, Tricia Loo Yi Jun, Shze Yung Koh, Melissa R. Pitman, Samuel Kwok, Jiajia Ma, Bo Hu, Fang Lin, Xue Li Lok, Stuart M. Pitson, Timothy E. Saunders, Tom J. Carney
SUMMARYImmigration of mesenchymal cells into the growing fin and limb buds drives distal outgrowth, with subsequent tensile forces between these cells essential for fin and limb morphogenesis. Morphogens derived from the apical domain of the fin, ori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bf2a0f428add986485656b4fb9176e5
https://doi.org/10.1101/2021.12.07.471519
https://doi.org/10.1101/2021.12.07.471519
Autor:
Thomas J. Carney, Changqing Zhang, Lynda J. Partridge, Claire A. Scott, Jiajia Ma, Vinay Tergaonkar, Ser Sue Ng, Sudipto Roy, Ying Na Ho, Katherine S. Marsay, Harsha Mahabaleshwar, Weibin Zhang, Christopher K.J. Teow, Enrique Amaya
Publikováno v:
eLife, Vol 10 (2021)
eLife
Ma, J, Scott, C A, Ho, Y N, Mahabaleshwar, H, Marsay, K S, Zhang, C, Teow, C K J, Ng, S S, Zhang, W, Tergaonkar, V, Partridge, L J, Roy, S, Amaya, E & Carney, T J 2021, ' Matriptase activation of gq drives epithelial disruption and inflammation via RSK and DUOX ', eLife, vol. 10, e66596 . https://doi.org/10.7554/eLife.66596
eLife
Ma, J, Scott, C A, Ho, Y N, Mahabaleshwar, H, Marsay, K S, Zhang, C, Teow, C K J, Ng, S S, Zhang, W, Tergaonkar, V, Partridge, L J, Roy, S, Amaya, E & Carney, T J 2021, ' Matriptase activation of gq drives epithelial disruption and inflammation via RSK and DUOX ', eLife, vol. 10, e66596 . https://doi.org/10.7554/eLife.66596
Epithelial tissues are primed to respond to insults by activating epithelial cell motility and rapid inflammation. Such responses are also elicited upon overexpression of the membrane-bound protease, Matriptase, or mutation of its inhibitor, Hai1. Un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d4a586741733a1e1e21c15e5546256
https://doi.org/10.7554/elife.66596
https://doi.org/10.7554/elife.66596
Autor:
Tergaonkar, Ying Na H, Linda Partridge, Harsha Mahabaleshwar, Sudipto Roy, Katherine S Marsay, Jiajia M, Scott Ca, Teow Ckj, Ser Sue N, Enrique Amaya, Chaoyang Zhang, Weibin Zhang, Thomas J. Carney
Tissues respond to damage by increasing inflammation and epithelial cell motility. How damage detection and responses are orchestrated is unclear. Overexpression of the membrane bound protease, Matriptase, or mutation of its inhibitor, Hai1, results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b59495368eace00ce5367ca02c1f343
https://doi.org/10.1101/2021.01.21.427549
https://doi.org/10.1101/2021.01.21.427549
Autor:
Thomas J. Carney, Katherine S Marsay, Harsha Mahabaleshwar, Charmaine Min Ho, Sarah Greaves, Lynda J. Partridge, Henry Roehl, Peter N. Monk
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0260372 (2021)
PLoS ONE
PLoS ONE
Collective cell migration is essential for embryonic development and homeostatic processes. During zebrafish development, the posterior lateral line primordium (pLLP) navigates along the embryo flank by collective cell migration. The chemokine recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::139d5c6adaffb3bcbad43baf11173ccb
https://hdl.handle.net/10356/163099
https://hdl.handle.net/10356/163099