Výsledky vyhledávání - "Harsha Hapugaswatta"

Akademický článek

Differential expression of microRNA, miR-150 and enhancer of zeste homolog 2 (EZH2) in peripheral blood cells as early prognostic markers of severe forms of dengue

Autor: Harsha Hapugaswatta, Pubudu Amarasena, Ranjan Premaratna, Kapila N. Seneviratne, Nimanthi Jayathilaka

Publikováno v: Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-9 (2020)

Abstract Background Dengue presents a wide clinical spectrum. Most patients recover following a self-limiting non-severe clinical course. A small proportion of patients progress to severe disease, mostly characterized by plasma leakage with or withou

Externí odkaz: https://doaj.org/article/73047663de834325b95217524d8969af

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Expression of Nitric Oxide Synthase and Nitric Oxide Levels in Peripheral Blood Cells and Oxidized Low-Density Lipoprotein Levels in Saliva as Early Markers of Severe Dengue

Autor: Nimanthi Jayathilaka, K.N. Seneviratne, Ranjan Premaratna, Suharshi S. Perera, Harsha Hapugaswatta, Ruwani L. Wimalasekara

Publikováno v: BioMed Research International, Vol 2021 (2021)
BioMed Research International

Background. Severe dengue (SD), experienced by only a fraction of dengue patients, can be lethal. Due to the lack of early markers that can predict the evolution of SD, all dengue patients have to be monitored under hospital care. We discovered early

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2d59780312597d6dbae65cae43dfa7

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Effect of Chain Length and Saturation of the Fatty Acids in Dietary Triglycerides on Lipid Metabolism in Wistar Rats

Autor: Nimanthi Jayathilaka, C.M. Senanayake, Harsha Hapugaswatta, K.N. Seneviratne, Gangi R Samarawickrama

We investigated the effect of the chain length and the degree of saturation of fatty acids in dietary triglycerides on serum lipid profiles and hepatic lipid metabolism in Wistar rats. Fat component of the basal diet (soybean oil) was replaced with f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e2583c30e267c54fa42b896ed1e05de
https://doi.org/10.26434/chemrxiv.12251519.v1

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Protective Effect of Coconut Oil Meal Phenolic Antioxidants against Macromolecular Damage: In Vitro and In Vivo Study

Autor: C.M. Senanayake, K.N. Seneviratne, Harsha Hapugaswatta, Nimanthi Jayathilaka, A. N. Karunasiri

Publikováno v: Journal of Chemistry, Vol 2020 (2020)

Coconut oil meal, a cheap by-product of coconut oil production, is a rich source of phenolic antioxidants. Many age-related diseases are caused by reactive oxygen species- (ROS-) induced damage to macromolecules such as lipids, proteins, and DNA. In

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Differential expression of microRNA, miR-150 and enhancer of zeste homolog 2 (EZH2) in peripheral blood cells as early prognostic markers of severe forms of dengue

Autor: Ranjan Premaratna, Harsha Hapugaswatta, K.N. Seneviratne, Pubudu Amarasena, Nimanthi Jayathilaka

Publikováno v: Journal of Biomedical Science
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-9 (2020)

Background Dengue presents a wide clinical spectrum. Most patients recover following a self-limiting non-severe clinical course. A small proportion of patients progress to severe disease, mostly characterized by plasma leakage with or without hemorrh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d70cc85cfdeea3ead0d11df100c3d4c
http://europepmc.org/articles/PMC6969970

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MOESM1 of Differential expression of microRNA, miR-150 and enhancer of zeste homolog 2 (EZH2) in peripheral blood cells as early prognostic markers of severe forms of dengue

Autor: Harsha Hapugaswatta, Pubudu Amarasena, Premaratna, Ranjan, Kapila Seneviratne, Nimanthi Jayathilaka

Additional file 1: Table S1. Primers for microRNA genes for qRT-PCR analysis. Table S2. Primers for microRNA target genes for qRT-PCR analysis. Table S3. AST, ALT and HCT of patients from admission to discharge. Table S4. Relative expression of micro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59eea2303be2f162d030bc80960b5eb4

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Differential expression of selected microRNA and putative target genes in peripheral blood cells as early markers of severe forms of dengue

Autor: Ranjan Premaratna, Nimanthi Jayathilaka, Pubudu Amarasena, K.N. Seneviratne, Harsha Hapugaswatta

BackgroundDengue presents a wide clinical spectrum including asymptomatic dengue fever (DF) or severe forms, such as dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Early symptoms of DHF are similar to those of non-life-threatening DF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d20962dc2269d5d0cba6afba225beb

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Phenolic extracts of the leaves of Psidium guineense Sw. improve the shelf life of sunflower oil and baked cake and antioxidant status of Wistar rats

Autor: Nimanthi Jayathilaka, Harsha Hapugaswatta, K.N. Seneviratne, C.M. Senanayake

Publikováno v: Journal of Food Biochemistry. 42

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::58eeefe8e6289b7d5613f450e8909396
https://doi.org/10.1111/jfbc.12632

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