Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Harsha, Nagar"'
Autor:
Seonhee Kim, Ikjun Lee, Shuyu Piao, Harsha Nagar, Su-jeong Choi, Young-Rae Kim, Kaikobad Irani, Byeong Hwa Jeon, Cuk-Seong Kim
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
miR204 is found to inhibit cpt1a in mouse hepatocytes, which could play a role in promoting non-alcoholic fatty liver disease.
Externí odkaz:
https://doaj.org/article/1b8771ab0e83418684aa0f195bf0d48e
Autor:
Harsha Nagar, Sungmin Kim, Ikjun Lee, Seonhee Kim, Su-Jeong Choi, Shuyu Piao, Byeong Hwa Jeon, Sang-Ha Oh, Cuk-Seong Kim
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Keloids are a type of aberrant skin scarring characterized by excessive accumulation of collagen and extracellular matrix (ECM), arising from uncontrolled wound healing responses. While typically non-pathogenic, keloids are occasionally rega
Externí odkaz:
https://doaj.org/article/222206fa63144f6094cdf0776c494714
Autor:
Ikjun Lee, Shuyu Piao, Seonhee Kim, Harsha Nagar, Su-jeong Choi, Minsoo Kim, Giang-Huong Vu, Byeong-Hwa Jeon, Cuk-Seong Kim
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 585 (2023)
Endothelial senescence impairs vascular function and thus is a primary event of age-related vasculature diseases. Isocitrate dehydrogenase 2 (IDH2) plays an important role in inducing alpha-ketoglutarate (α-KG) production and preserving mitochondria
Externí odkaz:
https://doaj.org/article/dda2c14f9a0e4f93aec57faf67430351
Autor:
Harsha Nagar, Seonhee Kim, Ikjun Lee, Su-Jeong Choi, Shuyu Piao, Byeong Hwa Jeon, Minho Shong, Cuk-Seong Kim
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0256646 (2021)
Rho GDP-dissociation inhibitor (RhoGDI), a downregulator of Rho family GTPases, prevents nucleotide exchange and membrane association. It is responsible for the activation of Rho GTPases, which regulate a variety of cellular processes, such as migrat
Externí odkaz:
https://doaj.org/article/e6a8be85a3e04f38bb339e5682a1a1a4
Autor:
Su-jeong Choi, Harsha Nagar, Jun Wan Lee, Seonhee Kim, Ikjun Lee, Shuyu Piao, Byeong Hwa Jeon, Cuk-Seong Kim
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 187 (2022)
Syndecan-2 (SDC2), a cell-surface heparin sulfate proteoglycan of the glycocalyx, is mainly expressed in endothelial cells. Although oxidative stress and inflammatory mediators have been shown to mediate dysfunction of the glycocalyx, little is known
Externí odkaz:
https://doaj.org/article/9349856846ae4d6a86443a1449485888
Publikováno v:
Acute and Critical Care, Vol 33, Iss 2, Pp 65-72 (2018)
Mitochondria are considered the power house of the cell and are an essential part of the cellular infrastructure, serving as the primary site for adenosine triphosphate production via oxidative phosphorylation. These organelles also release reactive
Externí odkaz:
https://doaj.org/article/843cc8f49efe4952933b6ee165082ff7
Autor:
Ikjun Lee, Shuyu Piao, Seonhee Kim, Harsha Nagar, Su-Jeong Choi, Byeong Hwa Jeon, Sang-Ha Oh, Kaikobad Irani, Cuk-Seong Kim
Publikováno v:
Antioxidants, Vol 10, Iss 11, p 1645 (2021)
Elevated plasma homocysteine levels can induce vascular endothelial dysfunction; however, the mechanisms regulating homocysteine metabolism in impaired endothelial cells are currently unclear. In this study, we deleted the essential mitoribosomal gen
Externí odkaz:
https://doaj.org/article/b96589ec9a694c9880c8d88e7f70f8a6
Autor:
Shuyu Piao, Ikjun Lee, Seon-Ah Jin, Seonhee Kim, Harsha Nagar, Su-jeong Choi, Byeong Hwa Jeon, Cuk-Seong Kim
Publikováno v:
Biomedicines, Vol 9, Iss 1, p 52 (2021)
The CR6-interacting factor1 (CRIF1) mitochondrial protein is indispensable for peptide synthesis and oxidative phosphorylation. Cardiomyocyte-specific deletion of CRIF1 showed impaired mitochondrial function and cardiomyopathy. We developed an endoth
Externí odkaz:
https://doaj.org/article/11191558e0f448c88e21ff5553e300ec
Autor:
Kwon, Sun Kwan, Ahn, Moonsang, Song, Hee-Jung, Kang, Shin Kwang, Jung, Saet-Byel, Harsha, Nagar, Jee, Sungju, Moon, Jae Young, Suh, Kwang-Sun, Lee, Sang Do, Jeon, Byeong Hwa, Kim, Dong Woon, Kim, Cuk-Seong
Publikováno v:
In Brain Research 19 November 2015 1627:12-20
Rg3-enriched Korean Red Ginseng enhances blood pressure stability in spontaneously hypertensive rats
Publikováno v:
Integrative Medicine Research, Vol 5, Iss 3, Pp 223-229 (2016)
Background: Korean Red Ginseng (Panax ginseng) has been shown to exert antihypertensive effects. In particular, ginsenoside Rg3 is thought to be a potent modulator of vascular function. The present study was performed to examine the antihypertensive
Externí odkaz:
https://doaj.org/article/f2db37d13b2149df8e42c6d4dc1e601f