Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Harry W. Schroeder"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/7f1bf2216661469884586cc722e833bb
Autor:
Harry W. Schroeder
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/29544f6a1e6d4f88969d721525c12b9e
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/8121ae41d5f84a2a96f48729e28949b8
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The early B cell protein λ5 is an essential component of the surrogate light chain and the preB cell receptor (preBCR), which is critical for optimal B cell development. To investigate the effect of λ5 and/or B cells on bone acquisition over time,
Externí odkaz:
https://doaj.org/article/15db170947e74f048370f1ea0a8bab96
Autor:
Regine Stutz, Christopher Meyer, Elisabeth Kaiser, Sybelle Goedicke-Fritz, Harry W. Schroeder, Robert Bals, Christoph Haertel, Tobias Rogosch, Sebastian Kerzel, Michael Zemlin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract We hypothesized that the scarcity of N-nucleotides might contribute to the inability of the neonate to mount a robust allergic immune response. To test this, we used terminal deoxyribunucleotidyl Transferase deficient (TdT−/−) mice, whic
Externí odkaz:
https://doaj.org/article/5b8e090760254a5383816ea9541a8604
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Enrichment for tyrosine in immunoglobulin CDR-H3 is due in large part to natural selection of germline immunoglobulin DH sequence. We have previously shown that when DH sequence is modified to reduce the contribution of tyrosine codons, epitope recog
Externí odkaz:
https://doaj.org/article/a8fcb57474d4437589ee63fe551c1ad3
Autor:
Mohamed Khass, Michael Levinson, Robert L. Schelonka, Pratibha Kapoor, Peter D. Burrows, Harry W. Schroeder
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
We have previously shown that the sequence of the immunoglobulin diversity gene segment (DH) helps dictate the structure and composition of complementarity determining region 3 of the immunoglobulin heavy chain (CDR-H3). In order to test the role of
Externí odkaz:
https://doaj.org/article/3cf150bdafdc4230aa0d97bf6b5e9657
Autor:
Mohamed Khass, Robert L. Schelonka, Cun Ren Liu, Ada Elgavish, Laurence Morel, Peter D. Burrows, Harry W. Schroeder
Publikováno v:
Autoimmunity, Vol 50, Iss 1, Pp 42-51 (2017)
Systemic lupus erythematosus (SLE) is an autoimmune disease that reflects a failure to block the production of self-reactive antibodies, especially those that bind double-stranded DNA (dsDNA). Backcrossing the lupus-prone NZM2410 genome onto C57BL/6
Externí odkaz:
https://doaj.org/article/2ef3b21ff7e34da9a70feaecb725f69f
Autor:
Mohamed Khass, Harunur Rashid, Peter D. Burrows, S. Louis Bridges, Amjad Javed, Harry W. Schroeder
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
In the bone marrow, preB cells are found adjacent to the bone endosteum where bone synthesizing osteoblast and bone resorbing osteoclasts reside. Although there is evidence of interactions between preB and bone cells, the factors that contribute to s
Externí odkaz:
https://doaj.org/article/65451f14afe940b5bc16371d15674b97
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Sequential developmental checkpoints are used to “optimize” the B cell antigen receptor repertoire by minimizing production of autoreactive or useless immunoglobulins and enriching for potentially protective antibodies. The first and apparently m
Externí odkaz:
https://doaj.org/article/b5766ce4fe0648feacf1092e550c6313