Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Harry W. Rudel"'
Autor:
Flecken U, Westhoff C, Zahradnik Hp, Henzl Mr, Starr Rm, Lopez Lm, Roy S, Edelman A, Armstrong Ay, Jansen R, Scommegna A, Mumford Sl, Otterness C, Breckwoldt M, Kraut E, Hagenfeldt K, Chen M, Fred A. Kincl, Grey Tw, Hill Mj, Stewart Cj, Harry W. Rudel, Helmerhorst Fm, Bernholc A, Heitmann Rj, Gobburu J, Leake R, Gopalakrishnan M, Creinin
Publikováno v:
Contraception. 94:353-356
To understand the potential duration of action for Liletta®, we conducted this study to estimate levonorgestrel (LNG) release rates over approximately 5½years of product use.Clinical sites in the U.S. Phase 3 study of Liletta collected the LNG intr
Autor:
Harry W. Rudel, Fred A. Kincl
Publikováno v:
Archiv der Pharmazie. 319:615-624
The biological potency of steroid hormones was increased by formulation with cholesterol, or its esters, in proportions at which the drugs form a solid solution. Improved intestinal absorption was most likely achieved by increasing the contransport o
Autor:
Fred A. Kind, Harry W. Rudel
Publikováno v:
Acta Endocrinologica. 65:S5-S30
By convention, drug potency is a relationship between the administered dose and the biologic response. Drug availability to the organism is a function of a dosage form or formulation, »drug delivery system« and its metabolic fate, »drug removal sy
Publikováno v:
Journal of Steroid Biochemistry. 1:315-318
Determination of radioactivity in urine, faeces and various organs in rats was used to monitor the absorption of labelled 6-methyl-17α-acetoxy-4,6-pregnadiene-3,20-dione from polydimethylsiloxane implants or after oral administration. Given orally,
Autor:
Jorge Martínez-Manautou, Manuel Maqueo-Topete, Stuart Bessler, Thomas Lebherz, Harry W. Rudel
Publikováno v:
Reproduction. 13:199-203
Autor:
Malcolm M. Haring, Harry W. Rudel
Publikováno v:
Industrial & Engineering Chemistry. 22:1234-1237
Autor:
Harry W. Rudel
Publikováno v:
Clinical Obstetrics and Gynecology. 11:632-644
Control of fertility has been held synonymous with ovulation suppression however the therapeutic goal should be achieved with minimal disruption of physiology. Separation of fertility control from ovulation inhibition is a step towards more selective
Autor:
Joseph W. Goldzieher, Edmee Perez-Vega, Jorge Martínez-Manautou, Harry W. Rudel, Manuel Maqueo
Publikováno v:
American Journal of Obstetrics and Gynecology. 85:427-432
Studies were undertaken to compare the effects of various progestational steroids given over a 20 day period in the usual therapeutic dosage. Among the substances tested were norethynodrel norethindrone chlormadinone and oral progesterone. Biopsies w
Autor:
Harry W. Rudel, Fred A. Kincl
Publikováno v:
Acta Endocrinologica. 51:S7-S45
A review of studies into the biology of antifertility steroids conducted primarily at the Syntex Research Center is presented. The pituitary-hypothalamic axis is discussed. There has been considerable conjecture that the estrogens and progestogens ma
Publikováno v:
American Journal of Obstetrics and Gynecology. 106:122-127
Dose response, contraceptive efficacy, and menstrual cycle control were tested in 667 normal fertile women using daily oral administration of megestrol acetate (MA) in either an oil solution or a tablet form. The occurrence of a regular menstrual ble