Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Harry W. M. Steinbusch"'
Autor:
Nalaka Wijekoon, Lakmal Gonawala, Pyara Ratnayake, Roshan Liyanage, Dhammika Amaratunga, Yetrib Hathout, Harry W. M. Steinbusch, Ashwin Dalal, Eric P. Hoffman, K. Ranil D. de Silva
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-16 (2024)
Abstract Background The phenotype of Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) patients is determined by the type of DMD gene variation, its location, effect on reading frame, and its size. The primary objective of this in
Externí odkaz:
https://doaj.org/article/c4163d83d1134daf81f028ae6456712e
Autor:
Gowoon Son, Seung-Jun Yoo, Shinwoo Kang, Ameer Rasheed, Da Hae Jung, Hyunjun Park, Bongki Cho, Harry W. M. Steinbusch, Keun-A Chang, Yoo-Hun Suh, Cheil Moon
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-20 (2021)
Abstract Background Hyposmia in Alzheimer’s disease (AD) is a typical early symptom according to numerous previous clinical studies. Although amyloid-β (Aβ), which is one of the toxic factors upregulated early in AD, has been identified in many s
Externí odkaz:
https://doaj.org/article/a75572e81f3d46138b6947724da05a40
Autor:
Keith W. Whitaker, Frank M. LaFerla, Harry W. M. Steinbusch, Cynthia A. Lemere, Diane E. Bovenkamp
Publikováno v:
Molecular Neurodegeneration, Vol 14, Iss 1, Pp 1-4 (2019)
Abstract The 3 day workshop “Alzheimer’s Fast Track” is a unique opportunity for graduate students, postdoctoral fellows, or other early-career scientists, focused on Alzheimer’s disease research, to gain new knowledge and become an expert in
Externí odkaz:
https://doaj.org/article/32bf3c27443540808e00a2a4bbcfe3a5
Autor:
Takashi Koizumi, Katsutoshi Taguchi, Ikuko Mizuta, Hiroe Toba, Makoto Ohigashi, Okihiro Onishi, Kazuya Ikoma, Seiji Miyata, Tetsuo Nakata, Masaki Tanaka, Sébastien Foulquier, Harry W. M. Steinbusch, Toshiki Mizuno
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-13 (2019)
Abstract Background Microglia play crucial roles in the maintenance of brain homeostasis. Activated microglia show a biphasic influence, promoting beneficial repair and causing harmful damage via M2 and M1 microglia, respectively. It is well-known th
Externí odkaz:
https://doaj.org/article/2ac3ba0aeded49a8a1a8a69f325d216d
Autor:
Ana Luisa Gil-Martinez, Lorena Cuenca-Bermejo, Pablo Gallo-Soljancic, Consuelo Sanchez-Rodrigo, Virginia Izura, Harry W. M. Steinbusch, Emiliano Fernandez-Villalba, Maria Trinidad Herrero
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Background: Parkinson’s disease (PD) is described as an age-related neurodegenerative disorder. However, the vast majority of research is carried out using experimental models of young animals lacking the implications of the decline processes assoc
Externí odkaz:
https://doaj.org/article/67e9fff459f74d9b81543caf367b9bfb
Autor:
Takashi Koizumi, Danielle Kerkhofs, Toshiki Mizuno, Harry W. M. Steinbusch, Sébastien Foulquier
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Cerebral small vessels feed and protect the brain parenchyma thanks to the unique features of the blood–brain barrier. Cerebrovascular dysfunction is therefore seen as a detrimental factor for the initiation of several central nervous system (CNS)
Externí odkaz:
https://doaj.org/article/25cf3c6eb2764dd19fba4b6839b7be6b
Autor:
Magdalena T. Weidner, Roy Lardenoije, Lars Eijssen, Floriana Mogavero, Lilian P. M. T. De Groodt, Sandy Popp, Rupert Palme, Konrad U. Förstner, Tatyana Strekalova, Harry W. M. Steinbusch, Angelika G. Schmitt-Böhrer, Jeffrey C. Glennon, Jonas Waider, Daniel L. A. van den Hove, Klaus-Peter Lesch
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Converging evidence suggests a role of serotonin (5-hydroxytryptamine, 5-HT) and tryptophan hydroxylase 2 (TPH2), the rate-limiting enzyme of 5-HT synthesis in the brain, in modulating long-term, neurobiological effects of early-life adversity. Here,
Externí odkaz:
https://doaj.org/article/e9bfdfc3a3f543148df4c4b9e9207fcb
Autor:
Jodi L. Pawluski, Eva van Donkelaar, Zipporah Abrams, Virginie Houbart, Marianne Fillet, Harry W. M. Steinbusch, Thierry D. Charlier
Publikováno v:
Neural Plasticity, Vol 2014 (2014)
Selective serotonin reuptake inhibitor medications are one of the most common treatments for mood disorders. In humans, these medications are taken orally, usually once per day. Unfortunately, administration of antidepressant medications in rodent mo
Externí odkaz:
https://doaj.org/article/13c217d001544a9e890ba5df1e552d74
Publikováno v:
Progress in brain research. 261
The brainstem is a neglected brain area in neurodegenerative diseases, including Alzheimer's and Parkinson's disease, frontotemporal lobar degeneration and autonomic dysfunction. In Depression, several observations have been made in relation to chang
Autor:
Kenichiro Negishi, Mikayla A. Payant, Kayla S. Schumacker, Gabor Wittmann, Rebecca M. Butler, Ronald M. Lechan, Harry W. M. Steinbusch, Arshad M. Khan, Melissa J. Chee
Publikováno v:
Journal of Comparative Neurology. 528