Developmental fluoxetine exposure normalizes the long-term effects of maternal stress on post-operative pain in Sprague-Dawley rat offspring.

Autor: Liesbeth Knaepen, Ine Rayen, Thierry D Charlier, Marianne Fillet, Virginie Houbart, Maarten van Kleef, Harry W Steinbusch, Jacob Patijn, Dick Tibboel, Elbert A Joosten, Jodi L Pawluski

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e57608 (2013)

Early life events can significantly alter the development of the nociceptive circuit. In fact, clinical work has shown that maternal adversity, in the form of depression, and concomitant selective serotonin reuptake inhibitor (SSRI) treatment influen

Externí odkaz: https://doaj.org/article/5ac4146d44ca4586b4e67e0bc0dc968d

On the Blueprint of the Long Primary Afferent Axons and the Dichotomous Axon Trajectory of Clarke’s Nucleus. A Morphological Tracing Study on the Effect of Hypoxia during Development

Autor: Frits C. de Beer, Harry W. Steinbusch

Publikováno v: Anatomia, Vol 2, Iss 4, Pp 414-449 (2023)

The primary afferent system in the rat’s spinal cord starts to develop in the third last week of gestation. First, the pseudounipolar DRG neurons extend their centripetal long primary axons, targeting rostral supra-segmental nuclei in the spinal co

Externí odkaz: https://doaj.org/article/59ac2ce929a44889949b5a7ce64e4e8f

Behavioral Features of Mice Fed with a Cholesterol-Enriched Diet: Deficient Novelty Exploration and Unaltered Aggressive Behavior

Autor: Ekaterina Veniaminova, Raymond Cespuglio, Nataliia Markova, Niall Mortimer, Chi Wai Cheung, Harry W. Steinbusch, Klaus-Peter Lesch, Tatyana Strekalova

Publikováno v: Translational Neuroscience and Clinics. 2:87-95

Objectives Previous studies involving mice have demonstrated that a cholesterol-enriched diet evokes liver steatosis, dystrophy, inflammation, and aspects of nonalcoholic fatty liver disease (NAFLD). These changes are accompanied by the activation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f08a3d35812a4434cf11c95b2a94c1d
https://doi.org/10.18679/cn11-6030_r.2016.014

Lasting downregulation of the lipid peroxidation enzymes in the prefrontal cortex of mice susceptible to stress-induced anhedonia

Autor: Daniel C. Anthony, Brandon H. Cline, Konstantin V. Anokhin, Oleg Dolgov, Dmitry Malin, Harry W. Steinbusch, Tatyana Strekalova, Aslan Kubatiev, Careen A. Schroeter, Klaus-Peter Lesch, Alexander Lysko

Publikováno v: Behavioural Brain Research, 276, 118-129. Elsevier Science
Behavioural Brain Research
Behavioural Brain Research, Elsevier, 2015, 276, pp.118-129. ⟨10.1016/j.bbr.2014.04.037⟩
ResearcherID
Behavioural Brain Research, 2015, 276, pp.118-129. ⟨10.1016/j.bbr.2014.04.037⟩

International audience; Antioxidant enzymes and lipid peroxidation in the brain are involved in neuropsychiatric pathologies, including depression. 14- or 28-day chronic stress model induced a depressive syndrome defined by lowered reward sensitivity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d55813ea7510fdf15e4dc3c7528e6fd
https://cris.maastrichtuniversity.nl/en/publications/4333eb9c-2c24-4470-9137-d9b698efb048

Repetitive Intrathecal VEGF165Treatment Has Limited Therapeutic Effects after Spinal Cord Injury in the Rat.

Autor: Sabien van Neerven, Elbert A.J. Joosten, Gary A. Brook, Charles A. Lambert, Jörg Mey, Joachim Weis, Marco A. Marcus, Harry W. Steinbusch, Maarten van Kleef, Jaap Patijn, Ronald Deumens

Publikováno v: Journal of Neurotrauma; Oct2010, Vol. 27 Issue 10, p1781-1791, 11p