Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Harry S Nick"'
Autor:
Swati Khare, Jerelyn A Nick, Yalan Zhang, Kira Galeano, Brittany Butler, Habibeh Khoshbouei, Sruti Rayaprolu, Tyisha Hathorn, Laura P W Ranum, Lisa Smithson, Todd E Golde, Martin Paucar, Richard Morse, Michael Raff, Julie Simon, Magnus Nordenskjöld, Karin Wirdefeldt, Diego E Rincon-Limas, Jada Lewis, Leonard K Kaczmarek, Pedro Fernandez-Funez, Harry S Nick, Michael F Waters
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0173565 (2017)
The autosomal dominant spinocerebellar ataxias (SCAs) are a diverse group of neurological disorders anchored by the phenotypes of motor incoordination and cerebellar atrophy. Disease heterogeneity is appreciated through varying comorbidities: dysarth
Externí odkaz:
https://doaj.org/article/97e9d48d1cdd49d1b21e559becfb6f09
Autor:
John C Middlebrooks, Harry S Nick, S H Subramony, Joel Advincula, Raymond L Rosales, Lillian V Lee, Tetsuo Ashizawa, Michael F Waters
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76749 (2013)
Normal sound localization requires precise comparisons of sound timing and pressure levels between the two ears. The primary localization cues are interaural time differences, ITD, and interaural level differences, ILD. Voltage-gated potassium channe
Externí odkaz:
https://doaj.org/article/fede54f6a951423aaf26816e7dffb6c6
Autor:
Helmut Hiller, Martha Campbell-Thompson, Clive Wasserfall, Irina Kusmartseva, Maria Beery, Stephen Selman, Amanda L. Posgai, Michael J. Haller, Desmond A. Schatz, Myriam Padilla, Harry S. Nick, Mark A. Atkinson
Publikováno v:
Diabetes
Within the human pancreas, exocrine and endocrine cells control secretion of digestive enzymes and production of hormones to maintain metabolic homeostasis, respectively. While the vast majority of type 1 diabetes research efforts have focused on end
Autor:
William J. Greenleaf, Sarah A. Teichmann, Margaret Vella, Ajay Pillai, Aviv Regev, Ananda L. Roy, Kristin E. Burnum-Johnson, Cole Trapnell, Yiing Lin, Marda Jorgensen, Gloria S. Pryhuber, Leslie Gaffney, Ken S. Lau, Kimberly Robasky, Jeffrey M. Spraggins, Chuck McCallum, Stavros Michailidis, Randy Heiland, Orit Rozenblatt-Rosen, Allyson Ricarte, Xin bSun, Kevin J. Otto, Amir Bahmani, Zorina S. Galis, James S. Hagood, Monica Nagendran, Gökcen Eraslan, Robin M. Scibek, Jocelyn Y. Kishi, Jay Mulye, Maria Keays, Griffin M. Weber, Caltech-UW Tmc, Charles Ansong, Nicholas A. Nystrom, Vishal G. Venkataraaman, Vladimir Yu. Kiselev, Ucsd Tmc, Ellen M. Quardokus, Tushar bDesai, Bruce Herr, Engagement Component, James E. Anderson, Shin Lin, Lisel Record, Peter V. Kharchenko, Robert F. dMurphy, Stanford-WashU Tmc, Yu Wang, Jian Ma, Sergio Maffioletti, Sarah Black, Matthew Ruffalo, Salvatore Sechi, John C. Marioni, Ziv Bar-Joseph, Richard M. Caprioli, Stanford Ttd, Garry P. Nolan, Marishka Brown, Elizabeth L. Wilder, Maigan A. Brusko, Peter Chou, Tommaso Biancalani, Christian Martijn Schuerch, Julia Laskin, Richard Conroy, Jonathan C. Silverstein, Paula M. Mabee, Dena Procaccini, Pehr B. Harbury, Michael Snyder, Pothur Srinivas, Jennifer Rood, Dana Jackson, Sanjay Jain, Katy Börner, Visualization HuBMAP Integration, William E. Shirey, Sinem K. Saka, James P. Sluka, Agnes B. Fogo, Isabel Goldaracena, Sushma A. Akoju, Raymond C. Harris, Rahul Satija, Sylvia K. Plevritis, Tim Stuart, Shila Ghazanfar, Peng Yin, Harvard Ttd, Aaron M. Horning, Ed Esplin, Amanda Posgai, Michael J. Clare-Salzler, Raf Van de Plas, Aaron Pawlyk, Guo-Cheng Yuan, Benedict aten, DongHye Ye, Hayan Lee, Eyal Fisher, Jay Shendure, Long Cai, Danielle cGutierrez, Carl Kingsford, Ruben Dries, Sara Ahadi, Paul D. Piehowski, Bernd bBodenmiller, Purdue Ttd, Stephanie A. Nevins, Philip D. Blood, Andrew Butler, W. Christopher Lenhardt, Ying Zhu, Alexander J. Ropelewski, Harry S. Nick, Nathan Heath Patterson, Elizabeth K. Neumann, Anna Hupalowska, Samuel H. Friedman, Clive hWasserfall, Qian Zhu, Mark P. deCaestecker, Leonard E. Cross, Mark A. Atkinson, Paul Macklin, Todd M. Brusko, Eeshit Dhaval Vaishnav, Nils Gehlenborg, Kun Zhang
Publikováno v:
Nature
Transformative technologies are enabling the construction of three-dimensional maps of tissues with unprecedented spatial and molecular resolution. Over the next seven years, the NIH Common Fund Human Biomolecular Atlas Program (HuBMAP) intends to de
Autor:
Seth Currlin, Harry S. Nick, Marda Jorgensen, Jerelyn A. Nick, Maigan A. Brusko, Hunter Hakimian, Jesus Penaloza-Aponte, Natalie Rodriguez, Miguel Medina-Serpas, Mingder Yang, Robert P. Seifert, Irina Kusmartseva, Todd M. Brusko, Kevin Otto, Amanda L. Posgai, Clive H. Wasserfall, Mark A. Atkinson
SummaryThe spleen and lymph node represent important hubs for both innate and adaptive immunity1,2. Herein, we map immune, endothelial, and neuronal cell networks within these tissues from “normal”/non-diseased organ donors, collected through the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::788c69853cf6af023cda6599dfca7bad
https://doi.org/10.1101/2021.10.20.465151
https://doi.org/10.1101/2021.10.20.465151
Autor:
Clive Wasserfall, Andrew A. Butler, Harry S. Nick, Alsu Missarova, Todd M. Brusko, Mark A. Atkinson, Rahul Satija, John C. Marioni, Maigan A. Brusko, Tim Stuart, Shila Ghazanfar, Jaison Jain
The problem of selecting targeted gene panels that capture maximum variability encoded in scRNA-sequencing data has become of great practical importance. scRNA-seq datasets are increasingly being used to identify gene panels that can be probed using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f86ebce7c5dc30c3b9c81afc5bf7219e
https://doi.org/10.1101/2021.08.10.455720
https://doi.org/10.1101/2021.08.10.455720
Autor:
Richard A. Oram, Helmut Hiller, Joeseph J. Lebowitz, Habibeh Khoshbouei, Irina Kusmarteva, Mark A. Atkinson, Bernd Bodenmiller, Desmond A. Schatz, Dawn E. Beachy, Amanda L. Posgai, Douglas R. Miller, Clive Wasserfall, Justin Mason, Andrew T. Hattersley, Laura M. Jacobsen, Stefanie Engler, Harry S. Nick
Publikováno v:
Diabetes
Diabetes, 70 (8)
Diabetes, 70 (8)
Type 1 diabetes (T1D) has a multifactorial autoimmune etiology, involving environmental prompts and polygenic predisposition. We hypothesized that pancreata from individuals with and at risk for T1D would exhibit dysregulated expression of genes asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295eb2ed3df8f0a6b34d70ed66133d34
https://doi.org/10.5167/uzh-211581
https://doi.org/10.5167/uzh-211581
Autor:
Amanda L. Posgai, Harry S. Nick, Eduardo Candelario-Jalil, Clive Wasserfall, Mark A. Atkinson, Desmond A. Schatz, Dawn E. Beachy, Irina Kusmartseva, Changjun Yang, Helmut Hiller
Publikováno v:
Diabetologia
AIMS/HYPOTHESIS: Normal cellular prion protein (PrP(C)) is a conserved mammalian glycoprotein found on the outer plasma membrane leaflet through a glycophosphatidylinositol anchor. Although PrP(C) is expressed by a wide range of tissues throughout th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7a151ddfd0fce96beea01429fb4d75
https://europepmc.org/articles/PMC8715394/
https://europepmc.org/articles/PMC8715394/
Autor:
Changjun Yang, Fahim Syed, Harry S. Nick, Jack L. Harbert, Marda Jorgensen, Sirlene Cechin, Richard E. Lloyd, Mark A. Atkinson, Eduardo Candelario-Jalil, Verena van der Heide, Vander Heide Rs, Amanda L. Posgai, Wenting Wu, Carmella Evans-Molina, Tang X, Irina Kusmartseva, Martha Campbell-Thompson, Alberto Pugliese, Dirk Homann, Paul N. Joseph
SUMMARYDiabetes is associated with increased mortality from Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Given literature suggesting a potential association between SARS-CoV-2 infection and diabetes induction, we examined pancreatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84bc63a14d1cf9ea27c38420dd95667e
https://doi.org/10.1101/2020.08.31.270736
https://doi.org/10.1101/2020.08.31.270736
Autor:
Dawn E. Beachy, Brittany S. Bruggeman, Harry S. Nick, Clive Wasserfall, Mark A. Atkinson, Desmond A. Schatz, Laura M. Jacobsen
Publikováno v:
Diabetes. 69
Current evidence suggests that alteration in cellular metabolism leads to pancreatic β-cell dysfunction and loss in type 1 diabetes (T1D). The mammalian target of rapamycin, mTOR is a key regulator of cell survival and growth in response to intracel