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Examining the relationship between gray matter volume and a continuous measure of bipolarity in unmedicated unipolar and bipolar depression

Autor: Harry Rubin-Falcone, Reuben Heyman-Kantor, Ainsley K. Burke, Jeffrey M. Miller, J. John Mann, Mina M. Rizk, Yashar Yousefzadeh Fard, Maria A. Oquendo, Francesca Zanderigo, Matthew S. Milak, M. Elizabeth Sublette, Gregory M. Sullivan

Publikováno v: Journal of Affective Disorders. 280:105-113

It has been argued that unipolar major depressive disorder (MDD) and bipolar disorder (BD) exist on a continuous spectrum, given their overlapping symptomatology and genetic diatheses. The Bipolarity Index (BI) is a scale that considers bipolarity as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15aa93a459b3f80adc1016bfa6b96be9
https://doi.org/10.1016/j.jad.2020.10.071

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Smaller left hippocampal subfield CA1 volume is associated with reported childhood physical and/or sexual abuse in major depression: A pilot study

Autor: Harry Rubin-Falcone, M. Elizabeth Sublette, R. Todd Ogden, Xuejing Lin, Ainsley K. Burke, Minlan Yuan, J. John Mann, Maria A. Oquendo, Mina M. Rizk, Jeffrey M. Miller

Publikováno v: Journal of Affective Disorders. 272:348-354

Background Smaller hippocampal volumes are reported in adults with major depressive disorder (MDD) and in reported childhood abuse. The hippocampus is a complex structure with distinct functional subfields. We sought to examine the effect of MDD diag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060e707b33d9d9474a095e118a7c2da3
https://doi.org/10.1016/j.jad.2020.03.169

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Large-scale network dynamics in neural response to emotionally negative stimuli linked to serotonin 1A binding in major depressive disorder

Autor: Francesca Zanderigo, M. Elizabeth Sublette, Maria A. Oquendo, Jeffrey M. Miller, J. John Mann, Kevin N. Ochsner, Paul Sajda, Ainsley K. Burke, Harry Rubin Falcone, Noam Schneck, Barbara Stanley, Tao Tu

Publikováno v: Molecular psychiatry

Serotonergic dysfunction is implicated in major depressive disorder (MDD), but the mechanisms of this relationship remain elusive. Serotonin 1A (5-HT1A) autoreceptors regulate brain-wide serotonin neuron firing and are positioned to assert large-scal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c72aab3e7b5213b4b5402a7722f83d
https://doi.org/10.1038/s41380-020-0733-5

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Deficits of white matter axial diffusivity in bipolar disorder relative to major depressive disorder: No relationship to cerebral perfusion or body mass index

Autor: Harry Rubin-Falcone, Jonathan W. Stewart, J. John Mann, Maria A. Oquendo, Patrick J. McGrath, David J. Hellerstein, Francesca Zanderigo, M. Elizabeth Sublette, Martin J. Lan

Publikováno v: Bipolar Disorders. 22:296-302

Objective To compare white matter integrity (WMI) in bipolar disorder (BD) relative to healthy volunteers (HVs) and major depressive disorder (MDD). To determine the relationship of bipolar-specific differences in WMI to cerebral perfusion, body mass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ae89f6e1ee69743dc9d0b44ee73e865
https://doi.org/10.1111/bdi.12845

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Altered amygdala subregion-related circuits in treatment-naïve post-traumatic stress disorder comorbid with major depressive disorder

Autor: Harry Rubin-Falcone, Francesca Zanderigo, Jeffrey M. Miller, J. John Mann, Spiro P. Pantazatos, Cui Yuan, Wei Zhang, Su Lui, Hongru Zhu, Changjian Qiu, Yuchen Li, Qiyong Gong, Zhengjia Ren, Minlan Yuan

Publikováno v: Eur Neuropsychopharmacol

Individuals with both post-traumatic stress disorder and major depressive disorder (PTSD + MDD) often show greater social and occupational impairment and poorer treatment response than individuals with PTSD alone. Increasing evidence reveals that the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c03abc84363396511ea69240059946
https://doi.org/10.1016/j.euroneuro.2019.07.238

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Cortisol Stress Response and in Vivo PET Imaging of Human Brain Serotonin 1A Receptor Binding

Autor: J. John Mann, Maria A. Oquendo, Barbara Stanley, Louisa J. Steinberg, Hanga Galfalvy, Harry Rubin-Falcone, Eli Min, John G. Keilp, Jeffrey M. Miller, M. Elizabeth Sublette, Thomas B. Cooper, R. Todd Ogden, Joshua A. Kaufman

Publikováno v: International Journal of Neuropsychopharmacology

Background Abnormalities in the hypothalamic-pituitary-adrenal axis, serotonergic system, and stress response have been linked to the pathogenesis of major depressive disorder. State-dependent hyper-reactivity of the hypothalamic-pituitary-adrenal ax

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df72b4e14e3dd56108aea8db29149b6f
https://doi.org/10.1093/ijnp/pyz009

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Resting‐state amplitude of low‐frequency fluctuation is associated with suicidal ideation

Autor: Mina M. Rizk, M. Elizabeth Sublette, John G. Keilp, Harry Rubin-Falcone, Maria A. Oquendo, Martin J. Lan, Spiro P. Pantazatos, J. John Mann, Jeffrey M. Miller

Publikováno v: Depress Anxiety

Background Identifying brain activity patterns that are associated with suicidal ideation (SI) may help to elucidate its pathogenesis and etiology. Suicide poses a significant public health problem, and SI is a risk factor for suicidal behavior. Meth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc0aea8c773c9523b59d7537fa5c8e1
https://doi.org/10.1002/da.22888

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