Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Harry R, Davis"'
Autor:
Hong-Ping Guan, Xiaodong Yang, Ku Lu, Sheng-Ping Wang, Jose M. Castro-Perez, Stephen Previs, Michael Wright, Vinit Shah, Kithsiri Herath, Dan Xie, Daphne Szeto, Gail Forrest, Jing Chen Xiao, Oksana Palyha, Li-Ping Sun, Paula J. Andryuk, Samuel S. Engel, Yusheng Xiong, Songnian Lin, David E. Kelley, Mark D. Erion, Harry R. Davis, Liangsu Wang
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 11, Pp 2183-2195 (2015)
Glucagon and insulin have opposing action in governing glucose homeostasis. In type 2 diabetes mellitus (T2DM), plasma glucagon is characteristically elevated, contributing to increased gluconeogenesis and hyperglycemia. Therefore, glucagon receptor
Externí odkaz:
https://doaj.org/article/2172e3fff908429b99f72a94d0b8f239
Autor:
Marco Delsante, Raquel Fernandez, Maarten Hoek, Masayuki Mori, Robert Kutys, Clint L. Miller, Teruhiko Yoshida, Khun Zaw Latt, Rika Kawakami, Xiaoqing Zhao, Avi Z. Rosenberg, Ka Hyun Paek, Daniela T. Fuller, Kenji Kawai, Jeffrey B. Kopp, Atsushi Sakamoto, Myung K. Shin, Aloke V. Finn, Renu Virmani, Paul S. de Vries, Harry R. Davis, Frank D. Kolodgie, Yu Sato, Jurgen Heymann, Liang Guo, Anne Cornelissen, Elizabeth Binns-Roemer
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41:2201-2214
Objective: Reported associations between kidney risk variants (G1 and G2) in APOL1 (apolipoprotein L1), encoding APOL1, and cardiovascular disease have been conflicting. We sought to explore associations of APOL1 risk variants with cause of sudden de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43be40b053b7a8963d2dcf4153afc989
https://doi.org/10.1161/atvbaha.120.315788
https://doi.org/10.1161/atvbaha.120.315788
Autor:
Brandon Ason, Samnang Tep, Jr. Harry R. Davis, Yiming Xu, Glen Tetzloff, Beverly Galinski, Ferdie Soriano, Natalya Dubinina, Lei Zhu, Alice Stefanni, Kenny K. Wong, Marija Tadin-Strapps, Steven R. Bartz, Brian Hubbard, Mollie Ranalletta, Alan B. Sachs, W. Michael Flanagan, Alison Strack, Nelly A. Kuklin
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 4, Pp 679-687 (2011)
Reducing circulating LDL-cholesterol (LDL-c) reduces the risk of cardiovascular disease in people with hypercholesterolemia. Current approaches to reduce circulating LDL-c include statins, which inhibit cholesterol synthesis, and ezetimibe, which blo
Externí odkaz:
https://doaj.org/article/5914edaf91c54338b6cfc9ad1842ba30
Autor:
André J. Tremblay, Benoît Lamarche, Valéry Lemelin, Lizbeth Hoos, Suzanne Benjannet, Nabil G. Seidah, Jr. Harry R. Davis, Patrick Couture
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 3, Pp 558-565 (2011)
Inhibition of cholesterol synthesis by 3-hydroxy-3-methylglutaryl-CoA reductase (HMG-CoAR) inhibitors has been associated with an increase in intestinal cholesterol absorption. This study examined how HMG-CoAR inhibition by atorvastatin modulates exp
Externí odkaz:
https://doaj.org/article/e0fff4ce37b64fb288719a8b97956b60
Autor:
Umidakhon, Makhmudova, Dieter, Lütjohann, P Christian, Schulze, Harry R, Davis, Oliver, Weingärtner
Publikováno v:
Journal of the American College of Cardiology. 79:e151-e152
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c9f1384b4bbe4dd6d48b0402b48ddec
https://doi.org/10.1016/j.jacc.2021.10.047
https://doi.org/10.1016/j.jacc.2021.10.047
Publikováno v:
World Journal of Cardiology
More than twenty years ago, knowledge about the importance of cholesterol absorption and the potential therapeutic effect of its inhibition led to the discovery and clinical application of the first and only cholesterol absorption inhibitor to date -
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c77397f14cb813d0150a117b88dbe50f
https://pubmed.ncbi.nlm.nih.gov/34754397
https://pubmed.ncbi.nlm.nih.gov/34754397
Autor:
Rouyanne T. Ras, P. Barton Duell, Semone B. Myrie, Jean Baptiste Roullet, Robert A. Moreau, Peter B. Jones, Jogchum Plat, David Mymin, Stephen D. Turley, Richard E. Ostlund, David J. Baer, Elke A. Trautwein, Oliver Weingärtner, Kara L. Calkins, Helena Gylling, Javier Ochoa Reparaz, Dieter Lütjohann, Henry N. Ginsberg, Mohammad Moghadasian, Todd C Rideout, Tim Vanmierlo, Harry R. Davis, David J.A. Jenkins, Dylan S. MacKay, Maryam Shamloo
Publikováno v:
Nutrition reviews, vol 76, iss 10
Current evidence indicates that foods with added plant sterols or stanols can lower serum levels of low-density lipoprotein cholesterol. This review summarizes the recent findings and deliberations of 31 experts in the field who participated in a sci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6290fa019d81ca4dd08c3f67bd4e30fe
https://doi.org/10.1093/nutrit/nuy032
https://doi.org/10.1093/nutrit/nuy032
Autor:
Martin Brandt, Masataka Nakano, Ye Qiao, Fumiyuki Otsuka, Liang Guo, Aloke V. Finn, Renu Virmani, Frank D. Kolodgie, Hugh H. Trout, Harry R. Davis, Xiao Qing Zhao, Colin H. Macphee, Bruce A. Wasserman, Elena Ladich, Sue Krug-Gourley, Qi Cheng
Publikováno v:
Atherosclerosis. 267:78-89
Background and aims Lipoprotein-associated phospholipase A2 (Lp-PLA2), an enzymatic inflammatory biomarker primarily bound to low-density lipoprotein cholesterol, is associated with an approximate twofold increased risk of cardiovascular disease and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9c2db0f84e7129ed07747b4515dcf3f
https://doi.org/10.1016/j.atherosclerosis.2017.10.014
https://doi.org/10.1016/j.atherosclerosis.2017.10.014
Autor:
Edwin Wang, Naif Zaman, Lorraine E. Chalifour, Miltiadis Paliouras, Bruce Gottlieb, Harry R. Davis, Shafinaz F. Chowdhury, Sandra Makhoul, Mark Trifiro, Morris Schweitzer, Lenore K. Beitel
Publikováno v:
Atherosclerosis. 246:78-86
Background Strategies to reduce LDL-cholesterol involve reductions in cholesterol synthesis or absorption. We identified a familial hypercholesterolemia patient with an exceptional response to the cholesterol absorption inhibitor, ezetimibe. Niemann-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6209ef65fa2512f96c609000a826115c
https://doi.org/10.1016/j.atherosclerosis.2015.12.032
https://doi.org/10.1016/j.atherosclerosis.2015.12.032
Autor:
Andrew J. Connolly, Lars Maegdefessel, Xiaoqing Zhao, Harry R. Davis, Jianqin Ye, Ljubica Perisic, Vivek Nanda, Kevin T. Nead, Daniel Direnzo, Joshua M. Spin, Sonny Dandona, Liang Guo, Kelly P. Downing, Frank D. Kolodgie, Sophia Xiao, Renu Virmani, Jessie Dalman, Ulf Hedin, Nicholas J. Leeper, Yoko Kojima
Publikováno v:
Circulation research, vol 118, iss 2
Rationale: Genetic variation at the chromosome 9p21 cardiovascular risk locus has been associated with peripheral artery disease, but its mechanism remains unknown. Objective: To determine whether this association is secondary to an increase in ather
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ebf944afd8cb3a25138e85bde367b4
https://doi.org/10.1161/circresaha.115.307906
https://doi.org/10.1161/circresaha.115.307906