Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Harry Pantazopoulos"'
Autor:
Christopher A. Martinez, Harry Pantazopoulos, Barbara Gisabella, Emily T. Stephens, Jacob Garteiser, Alberto Del Arco
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Repeated stress can predispose to substance abuse. However, behavioral and neurobiological adaptations that link stress to substance abuse remain unclear. This study investigates whether intermittent social defeat (ISD), a stress protocol th
Externí odkaz:
https://doaj.org/article/effde1a9be9a4b778918fd4c9e7c668a
Autor:
Jakob Hartmann, Thomas Bajaj, Joy Otten, Claudia Klengel, Tim Ebert, Anne-Kathrin Gellner, Ellen Junglas, Kathrin Hafner, Elmira A. Anderzhanova, Fiona Tang, Galen Missig, Lindsay Rexrode, Daniel T. Trussell, Katelyn X. Li, Max L. Pöhlmann, Sarah Mackert, Thomas M. Geiger, Daniel E. Heinz, Roy Lardenoije, Nina Dedic, Kenneth M. McCullough, Tomasz Próchnicki, Thomas Rhomberg, Silvia Martinelli, Antony Payton, Andrew C. Robinson, Valentin Stein, Eicke Latz, William A. Carlezon, Felix Hausch, Mathias V. Schmidt, Chris Murgatroyd, Sabina Berretta, Torsten Klengel, Harry Pantazopoulos, Kerry J. Ressler, Nils C. Gassen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract High levels of proinflammatory cytokines induce neurotoxicity and catalyze inflammation-driven neurodegeneration, but the specific release mechanisms from microglia remain elusive. Here we show that secretory autophagy (SA), a non-lytic moda
Externí odkaz:
https://doaj.org/article/83209dbad20940cdab3e3f6f4104353f
Autor:
Jake Valeri, Charlotte Stiplosek, Sinead M. O’Donovan, David Sinclair, Kathleen A. Grant, Ratna Bollavarapu, Donna M. Platt, Craig A. Stockmeier, Barbara Gisabella, Harry Pantazopoulos
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Contextual triggers are significant factors contributing to relapse in substance use disorders (SUD). Emerging evidence points to a critical role of extracellular matrix (ECM) molecules as mediators of reward memories. Chondroitin sulfate pr
Externí odkaz:
https://doaj.org/article/304450224fd54ef7b09e590ab5499d6c
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Substance use disorders are a global health problem with increasing prevalence resulting in significant socioeconomic burden and increased mortality. Converging lines of evidence point to a critical role of brain extracellular matrix (ECM) molecules
Externí odkaz:
https://doaj.org/article/926688d5d80441ffaa41fa2b19d09bed
Autor:
Emrah Yildiz, Gulcin Elboga, Merve Cıkılı Uygun, Rabia Yilmaz, Yavuz Selvi, Hasan Ulusal, Esra Çelik, Musa Sahpolat, Zeynep Zehra Yildiz, Onur Hursitoglu, Abdurrahman Altindag, Mehmet Tarakçıoğlu, Harry Pantazopoulos
Publikováno v:
Journal of Affective Disorders Reports, Vol 10, Iss , Pp 100406- (2022)
Background: Several lines of evidence indicate that circadian rhythm disruption is associated with bipolar disorder (BPD). This strong association, along with evidence from genome wide association studies (GWAS) implicating clock and clock controlled
Externí odkaz:
https://doaj.org/article/370a3c1fc6c343d49f1562a027637d06
Autor:
Jake Valeri, Sinead M. O’Donovan, Wei Wang, David Sinclair, Ratna Bollavarapu, Barbara Gisabella, Donna Platt, Craig Stockmeier, Harry Pantazopoulos
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Substance use disorders are a debilitating group of psychiatric disorders with a high degree of comorbidity with major depressive disorder. Sleep and circadian rhythm disturbances are commonly reported in people with substance use disorder and major
Externí odkaz:
https://doaj.org/article/27d040904880407eae09802b97a75dd9
Autor:
Harry Pantazopoulos, Sabina Berretta
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/e03e5c854bb84096a7b1cffaa82fed44
Autor:
Harry Pantazopoulos, Nayeem Mubarak Hossain, Gabriele Chelini, Peter Durning, Helen Barbas, Basilis Zikopoulos, Sabina Berretta
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 16 (2022)
Mounting evidence supports a key involvement of the chondroitin sulfate proteoglycans (CSPGs) NG2 and brevican (BCAN) in the regulation of axonal functions, including axon guidance, fasciculation, conductance, and myelination. Prior work suggested th
Externí odkaz:
https://doaj.org/article/d2fbd761d44147839e2dcc3669bfe7f5
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Sleep disturbances and memory dysfunction are key characteristics across psychiatric disorders. Recent advances have revealed insight into the role of sleep in memory consolidation, pointing to key overlap between memory consolidation processes and s
Externí odkaz:
https://doaj.org/article/b51dbcc694a745a5a0785f7ae1d9e989
Autor:
Darrick T. Balu, Harry Pantazopoulos, Cathy C.Y. Huang, Kevin Muszynski, Theresa Lynn Harvey, Yota Uno, Jacki M. Rorabaugh, Claire R. Galloway, Christian Botz-Zapp, Sabina Berretta, David Weinshenker, Joseph T. Coyle
Publikováno v:
Neurobiology of Disease, Vol 130, Iss , Pp 104511- (2019)
Although β-amyloid plaques are a well-recognized hallmark of Alzheimer's disease (AD) neuropathology, no drugs reducing amyloid burden have shown efficacy in clinical trials, suggesting that once AD symptoms emerge, disease progression becomes indep
Externí odkaz:
https://doaj.org/article/1a5c97093b8940d89bd516ac40a6131c