Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Harry M. Williams"'
Publikováno v:
PLoS Pathogens, Vol 19, Iss 1 (2023)
Bunyaviruses are negative sense, single-strand RNA viruses that infect a wide range of vertebrate, invertebrate and plant hosts. WHO lists three bunyavirus diseases as priority diseases requiring urgent development of medical countermeasures highligh
Externí odkaz:
https://doaj.org/article/e9996234bc2b47fd823fc89e40e322dc
Autor:
Tomas Kouba, Dominik Vogel, Sigurdur R. Thorkelsson, Emmanuelle R. J. Quemin, Harry M. Williams, Morlin Milewski, Carola Busch, Stephan Günther, Kay Grünewald, Maria Rosenthal, Stephen Cusack
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
The L protein of segmented, negative strand RNA viruses contains the RNA-dependent RNA polymerase essential for virus amplification. Here, the authors report cryoEM structures of the Lassa virus L protein in active, RNA-bound states, and provide mech
Externí odkaz:
https://doaj.org/article/97a04e7215a44a4ebaec52c71bff412e
Autor:
Robert D. Williams, Jennifer A. Moran, Anthony A. Fryer, Jamie R. Littlejohn, Harry M. Williams, Trevor J. Greenhough, Annette K. Shrive
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
A monomeric form of C-reactive protein (CRP) which precipitates with cell wall pneumococcal C polysaccharide (CWPS) and retains the ability to reversibly bind to its ligand phosphocholine has been produced through urea-induced dissociation at an opti
Externí odkaz:
https://doaj.org/article/415272d7cd764e23b41e2e584f851a77
Autor:
Harry M. Williams, Sigurdur R. Thorkelsson, Dominik Vogel, Morlin Milewski, Carola Busch, Stephen Cusack, Kay Grünewald, Emmanuelle R.J. Quemin, Maria Rosenthal
Publikováno v:
Nucleic Acids Research. 51:1424-1442
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a phenuivirus that has rapidly become endemic in several East Asian countries. The large (L) protein of SFTSV, which includes the RNA-dependent RNA polymerase (RdRp), is responsible for cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e80dc1c54412a8892278881bec6dd59
https://doi.org/10.1093/nar/gkac1249
https://doi.org/10.1093/nar/gkac1249
Autor:
Lennart Sänger, Harry M. Williams, Dingquan Yu, Dominik Vogel, Jan Kosinski, Maria Rosenthal, Charlotte Uetrecht
Lassa virus is a negative-strand RNA virus with only four structural proteins that causes periodic outbreaks in West Africa. The nucleoprotein (NP) encapsidates the viral genome, forming the ribonucleoparticles together with the viral RNA and the L p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c63f05f835ee8b03a52358112209f371
https://doi.org/10.1101/2023.02.09.527830
https://doi.org/10.1101/2023.02.09.527830
Autor:
Maria Rosenthal, S. Guenther, Kay Gruenewald, Sigurdur R. Thorkelsson, Morlin Milewski, Dominik Vogel, Tomáš Kouba, Carola Busch, Emmanuelle R. J. Quemin, Harry M. Williams, Stephen Cusack
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
'Nature Communications ', vol: 12, pages: 7018-1-7018-18 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
'Nature Communications ', vol: 12, pages: 7018-1-7018-18 (2021)
Lassa virus is endemic in West Africa and can cause severe hemorrhagic fever. The viral L protein transcribes and replicates the RNA genome via its RNA-dependent RNA polymerase activity. Here, we present nine cryo-EM structures of the L protein in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ea34ad14d5090bc89d87e86555ceb4
http://europepmc.org/articles/PMC8639829
http://europepmc.org/articles/PMC8639829
Autor:
Annette K. Shrive, Jamie R. Littlejohn, Harry M. Williams, William Neale, Stacey Collister, Derek Hood, Stefan Oscarson, Jens Madsen, Howard W. Clark, Trevor J. Greenhough
Human surfactant protein D is a collectin and member of the C-type lectin superfamily of proteins that forms an essential part of the mammalian innate immune system. The collectins have been recognised to not only bind to invading pathogens, allowing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61acc3d6380bafd1f23955b59c36a3f7
https://eprints.keele.ac.uk/10703/1/a59704.pdf
https://eprints.keele.ac.uk/10703/1/a59704.pdf
Autor:
Harry M. Williams, Jennifer A. Moran, Robert D. Williams, Trevor J. Greenhough, Anthony A. Fryer, Annette K. Shrive, Jamie R. Littlejohn
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
A monomeric form of C-reactive protein (CRP) which precipitates with cell wall pneumococcal C polysaccharide (CWPS) and retains the ability to reversibly bind to its ligand phosphocholine has been produced through urea-induced dissociation at an opti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694204c5b688cbb15838604de46e0aeb
https://eprints.keele.ac.uk/7608/1/fimmu-11-00115.pdf
https://eprints.keele.ac.uk/7608/1/fimmu-11-00115.pdf
Autor:
James H. McBurney, H. L. Mencken, Falk Johnson, Virgil C. Aldrich, H. P. Constans, A. T. Weaver, Howard Gilkinson, Thorrel B. Fest, Harry M. Williams, John Black, John Snidecor, M. D. Steer, C. Agnes Rigney, Margaret Parret, Elise Hahn, Loren D. Reid
Publikováno v:
Quarterly Journal of Speech. 34:501-509
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de02edee7134312713de0518f24c0812
https://doi.org/10.1080/00335634809381444
https://doi.org/10.1080/00335634809381444
Autor:
Harry M. Williams
Publikováno v:
Quarterly Journal of Speech. 35:329-333
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ef2d46e87f42a96961dcc8561414c34
https://doi.org/10.1080/00335634909381501
https://doi.org/10.1080/00335634909381501