Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Harry K. MacWilliams"'
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9676 (2010)
BACKGROUND: In the genesis of many tissues, a phase of cell proliferation is followed by cell cycle exit and terminal differentiation. The latter two processes overlap: genes involved in the cessation of growth may also be important in triggering dif
Externí odkaz:
https://doaj.org/article/40474cf870954d6f8c0c24745453d971
Autor:
Thomas Peis, Roberto Pedrola, Gytha Dollman, D. Grassi, Harry K. MacWilliams, Kimchi Doquang, Adrian Tsang, Adriano Ceccarelli
Publikováno v:
Development. 133:1287-1297
We describe rblA , the Dictyostelium ortholog of the retinoblastoma susceptibility gene Rb . In the growth phase, rblA expression is correlated with several factors that lead to `preference9 for the spore pathway. During multicellular development, ex
Autor:
Quyen Arana, Tongyao Liu, Lilian Chooback, Margaret Clarke, Zeno Dal Sacco, Christian Mirschberger, Harry K. MacWilliams
Publikováno v:
Journal of Cell Science. 115:1907-1918
The vacuolar proton pump (V-ATPase) appears to be essential for viability of Dictyostelium cells. To investigate the function of VatM, the 100 kDa transmembrane V-ATPase subunit, we altered its level. By means of homologous recombination, the promote
Autor:
Shirin Friedel, Anne Detterbeck, Ursula Hamker, Heike Deichsel, Catharine Coyne, Harry K. MacWilliams
Publikováno v:
Development Genes and Evolution. 209:63-68
We describe two modifications of the popular reporter green fluorescent protein (GFP) which have short half-lives in our system, the cellular slime mould Dictyostelium discoideum. One of these bears an N-terminal ubiquitin; this GFP was originally pl
Autor:
Ursula Hamker, Marie-Noëlle Simon, Birgit W. Wetterauer, Michel Véron, Harry K. MacWilliams, Arndt von Haeseler
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1265(1):97-101
DdKinX codes for 1093 amino acids which are organized in four regions: the N-terminal catalytic domain, a region containing 30% acidic amino acids, tandem repeats of the motif VKVEEPVEE and the C-terminus. Identity with other protein kinases is 25 to
Autor:
Kazuo Yamamoto, Harry K. MacWilliams, Mariko Omatsu-Kanbe, Yasuo Maeda, Aiko Amagai, Takahiro Isono, Shinya Urano
Publikováno v:
International Journal of Cell Biology
International Journal of Cell Biology, Vol 2012 (2012)
International Journal of Cell Biology, Vol 2012 (2012)
We have previously demonstrated that a novel protein ZYG1 induces sexual cell fusion (zygote formation) ofDictyosteliumcells. In the process of cell fusion, involvements of signal transduction pathways via Ca2+and PKC (protein kinase C) have been sug
Publikováno v:
Developmental Biology. 159:184-195
Discoidins are proteins, coded by a multigene family, which are regulated by extracellular factors during growth and development of Dictyostelium discoideum. In this paper we describe the isolation and characterization of mutants which misregulate th
Publikováno v:
Developmental Biology. 156:481-489
Dictyostelium discoideum forms elongate cell aggregates called "slugs" which migrate over the substrate before completing their conversion into fruiting bodies. Prespore cells are found in a zone which occupies the rear four-fifths of the slug. Both
Publikováno v:
Nucleic Acids Research. 21:1397-1401
The discoidin proteins of Dictyostelium discoideum are highly expressed during development. The Disc I gamma promoter allows the regulation of heterologous protein expression by experimental conditions. We report conditions under which the promoter a
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9676 (2010)
PLoS ONE
PLoS ONE
BACKGROUND: In the genesis of many tissues, a phase of cell proliferation is followed by cell cycle exit and terminal differentiation. The latter two processes overlap: genes involved in the cessation of growth may also be important in triggering dif