Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Harry H Matundan"'
Autor:
Ujjaldeep Jaggi, Harry H Matundan, Jack Yu, Satoshi Hirose, Mathias Mueller, Floyd L Wormley, Homayon Ghiasi
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009999 (2021)
Ocular HSV-1 infection is a major cause of eye disease and innate and adaptive immunity both play a role in protection and pathology associated with ocular infection. Previously we have shown that M1-type macrophages are the major and earliest infilt
Externí odkaz:
https://doaj.org/article/fc977b80a51a4b22958b32729e59586c
Autor:
Ujjaldeep Jaggi, Mingjie Yang, Harry H Matundan, Satoshi Hirose, Prediman K Shah, Behrooz G Sharifi, Homayon Ghiasi
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008971 (2020)
After HSV-1 infection, macrophages infiltrate early into the cornea, where they play an important role in HSV-1 infection. Macrophages are divided into M1 or M2 groups based on their activation. M1 macrophages are pro-inflammatory, while M2 macrophag
Externí odkaz:
https://doaj.org/article/c45410c76a094182a425b9337d97f4e9
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47696 (2012)
The UDP-glucuronosyltransferase (UGT) family of enzymes plays a vital role in the detoxification of carcinogens as well as clearance of anti-cancer drugs. In humans, 19 UGT family members have been identified and are expressed in a tissue specific ma
Externí odkaz:
https://doaj.org/article/696f0bd524bc4c6b8a5e5a508dcc672d
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3572 (2008)
Crosses between natural populations of two species of deer mice, Peromyscus maniculatus (BW), and P. polionotus (PO), produce parent-of-origin effects on growth and development. BW females mated to PO males (bwxpo) produce growth-retarded but otherwi
Externí odkaz:
https://doaj.org/article/13bad2d3cce8440690b39c2c9c9bd52c
Autor:
Satoshi Hirose, Shaohui Wang, Ujjaldeep Jaggi, Harry H. Matundan, Mihoko Kato, Xue-Ying Song, Sara J. Molesworth-Kenyon, Robert N. Lausch, Homayon Ghiasi
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Previously we reported that a recombinant HSV-1 expressing murine IL-2 (HSV-IL-2) causes CNS demyelination in different strains of mice and in a T cell-dependent manner. Since TH17 cells have been implicated in CNS pathology, in the present study, we
Externí odkaz:
https://doaj.org/article/6dec023a402c4ed3b35b88e5581101fd
Publikováno v:
mSphere, Vol 7, Iss 5 (2022)
ABSTRACT Over the past 70 years, multiple approaches to develop a prophylactic or therapeutic vaccine to control herpes simplex virus (HSV) infection have failed to protect against primary infection, reactivation, or reinfection. In contrast to many
Externí odkaz:
https://doaj.org/article/8ec1f841af3447e8ad8510eb9350fae4
Publikováno v:
J Virol
Macrophages are one of the first innate immune infiltrates in the cornea of mice following ocular infection with herpes simplex virus 1 (HSV-1). Using gamma interferon (IFN-γ) and interleukin-4 (IL-4) injections to polarize macrophages into M1 and M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41635af8b4514af67a2e8186fafeb571
https://europepmc.org/articles/PMC9645210/
https://europepmc.org/articles/PMC9645210/
Autor:
Kati Tormanen, Harry H. Matundan, Shaohui Wang, Ujjaldeep Jaggi, Kevin R. Mott, Homayon Ghiasi
Publikováno v:
J Virol
The HSV-1 latency-associated transcript (LAT) locus contains two small noncoding RNA (sncRNA) sequences (sncRNA1 and sncRNA2) that are not microRNAs (miRNAs). We recently reported that sncRNA1 is more important for in vitro activation of the herpesvi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7e50d885362f184420be61e14bf83f
https://europepmc.org/articles/PMC9006899/
https://europepmc.org/articles/PMC9006899/
Herpes Simplex Virus 1 Small Noncoding RNAs 1 and 2 Activate the Herpesvirus Entry Mediator Promoter
Publikováno v:
J Virol
Herpes simplex virus 1 (HSV-1) latency-associated transcript (LAT) plays a significant role in efficient establishment of latency and reactivation. LAT has antiapoptotic activity and downregulates expression of components of the type I interferon pat
Autor:
Mathias Mueller, Satoshi Hirose, Jack C. Yu, Ujjaldeep Jaggi, Harry H. Matundan, Homayon Ghiasi, Floyd L. Wormley
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 10, p e1009999 (2021)
PLoS Pathogens, Vol 17, Iss 10, p e1009999 (2021)
Ocular HSV-1 infection is a major cause of eye disease and innate and adaptive immunity both play a role in protection and pathology associated with ocular infection. Previously we have shown that M1-type macrophages are the major and earliest infilt