Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Harry D, Green"'
Autor:
Pavel Loginovic, Feiyi Wang, Jiang Li, Lauric Ferrat, Uyenlinh L. Mirshahi, H. Shanker Rao, Axel Petzold, Jessica Tyrrell, Harry D. Green, Michael N. Weedon, Andrea Ganna, Tiinamaija Tuomi, David J. Carey, UKBB Eye & Vision Consortium, FinnGen, Geisinger-Regeneron DiscovEHR Collaboration, Richard A. Oram, Tasanee Braithwaite
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Optic neuritis (ON) is associated with numerous immune-mediated inflammatory diseases, but 50% patients are ultimately diagnosed with multiple sclerosis (MS). Differentiating MS-ON from non-MS-ON acutely is challenging but important; non-MS
Externí odkaz:
https://doaj.org/article/f6426afe6a114af2b693c61ff64bdbc0
Autor:
Harry D. Green, Alistair Jones, Jonathan P. Evans, Andrew R. Wood, Robin N. Beaumont, Jessica Tyrrell, Timothy M. Frayling, Christopher Smith, Michael N. Weedon
Publikováno v:
PLoS Genetics, Vol 17, Iss 6 (2021)
Frozen shoulder is a painful condition that often requires surgery and affects up to 5% of individuals aged 40–60 years. Little is known about the causes of the condition, but diabetes is a strong risk factor. To begin to understand the biological
Externí odkaz:
https://doaj.org/article/743bd257e1b14cf6b5f8eab1ed15787d
Autor:
Rebecca J. Moon, Harry D. Green, Stefania D’Angelo, Keith M. Godfrey, Justin H. Davies, Elizabeth M. Curtis, Cyrus Cooper, Nicholas C. Harvey
Summary: Systematic review and meta-analysis of the effect of moderate- to high-dose vitamin D supplementation in pregnancy on offspring bone mineralisation found a positive effect of vitamin D supplementation on offspring bone mineral density (BMD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b718402604bdc77178127d76da2a574
https://eprints.soton.ac.uk/476467/
https://eprints.soton.ac.uk/476467/
Autor:
Harry D Green, Samuel WD Merriel, Richard A Oram, Katherine S Ruth, Jessica Tyrrell, Samuel E Jones, Chrissie Thirlwell, Mireille Gillings, Michael N Weedon, Sarah ER Bailey
Publikováno v:
Green, H D, Merriel, S WD, Oram, R A, Ruth, K S, Tyrrell, J, Jones, S E, Thirlwell, C, Gillings, M, Weedon, M N & Bailey, S ER 2022, ' Applying a genetic risk score for prostate cancer to men with lower urinary tract symptoms in primary care to predict prostate cancer diagnosis: a cohort study in the UK Biobank ', British Journal of Cancer, vol. 127, pp. 1534–1539 . https://doi.org/10.1038/s41416-022-01918-z
ObjectivesTo assess how accurately a genetic risk score (GRS) can identify incident prostate cancer in men seeing their general practitioner with lower urinary tract symptoms.DesignCohort study.SettingUK Biobank data linked to primary care records.Pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc9b85a19f28b9818bd96c340ebd9a3
http://hdl.handle.net/10138/353927
http://hdl.handle.net/10138/353927
Autor:
Harry D, Green, Samuel W D, Merriel, Richard A, Oram, Katherine S, Ruth, Jessica, Tyrrell, Samuel E, Jones, Chrissie, Thirlwell, Michael N, Weedon, Sarah E R, Bailey
Publikováno v:
British journal of cancer.
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Atrial fibrillation (AF), the most prevalent cardiac arrhythmia, is commonly initiated by ectopic beats originating from a small myocardial sleeve extending over the pulmonary veins. Pulmonary vein isolation therapy attempts to isolate the pulmonary
Externí odkaz:
https://doaj.org/article/d70c5fd86df64eedbe8e7653145e511a
Autor:
Robin N Beaumont, Nicholas A. Kennedy, Samuel E. Jones, Benjamin Hamilton, Jessica Tyrrell, Timothy M. Frayling, Andrew R. Wood, Tariq Ahmad, Harry D Green, Michael N. Weedon, James R Goodhand, Hanieh Yaghootkar
Publikováno v:
International Journal of Epidemiology
Background Gastro-oesophageal reflux disease (GORD) is associated with multiple risk factors but determining causality is difficult. We used a genetic approach [Mendelian randomization (MR)] to identify potential causal modifiable risk factors for GO
Autor:
Peter M. Irving, Guy Chung-Faye, Nicholas A. Kennedy, Tariq Ahmad, Ellina Lytvyak, Alexander Spiers, James R Goodhand, Timothy Harrower, Neil Chanchlani, Gareth J. Walker, Graham A. Heap, Harry D Green, JR Fraser Cummings, Alasdair Coles, Neel Heerasing, Eli Silber, Andrew R. Wood, R. Martin, Peter Hendy, Michael N. Weedon, Benjamin Hamilton, Mark S. Silverberg, Jeremy Hobart, Robin N Beaumont, Jessica Tyrrell, Simeng Lin, Vibeke Andersen
Publikováno v:
Lin, S, Green, H D, Hendy, P, Heerasing, N M, Chanchlani, N, Hamilton, B, Walker, G J, Heap, G A, Hobart, J, Martin, R J, Coles, A J, Silverberg, M S, Irving, P M, Chung-Faye, G, Silber, E, Cummings, JR F, Lytvyak, E, Andersen, V, Wood, A R, Tyrrell, J, Beaumont, R N, Weedon, M N, Kennedy, N A, Spiers, A, Harrower, T, Goodhand, J R, Ahmad, T & PRED4 study group 2020, ' Clinical features and genetic risk of demyelination following anti-TNF treatment ', Journal of Crohn's and Colitis, vol. 14, no. 12, pp. 1653-1661 . https://doi.org/10.1093/ecco-jcc/jjaa104
Background Anti-TNF exposure has been linked to demyelination events. We sought to describe the clinical features of demyelination events following anti-TNF treatment and to test whether affected patients were genetically predisposed to multiple scle
Linear mixed effects models are frequently used in biomedical statistics to model the trajectory of a repeatedly measured longitudinal variable, such as a biomarker, over time. However, population-level estimates may be biased by censoring bias resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17282241a456232257126f1263b45f74
https://doi.org/10.1101/2021.06.17.448796
https://doi.org/10.1101/2021.06.17.448796
Autor:
Christopher D. Smith, Michael N. Weedon, Alistair Jones, Jessica Tyrrell, Jonathan P Evans, Harry D Green, Robin N Beaumont, Timothy M. Frayling, Andrew R. Wood
Publikováno v:
PLoS Genetics, Vol 17, Iss 6 (2021)
PLoS Genetics
PLoS Genetics, Vol 17, Iss 6, p e1009577 (2021)
PLoS Genetics
PLoS Genetics, Vol 17, Iss 6, p e1009577 (2021)
Frozen shoulder is a painful condition that often requires surgery and affects up to 5% of individuals aged 40–60 years. Little is known about the causes of the condition, but diabetes is a strong risk factor. To begin to understand the biological