Three-Year, Randomized, Sham-Controlled Trial of Dexamethasone Intravitreal Implant in Patients with Diabetic Macular Edema

Autor: David S. Boyer, 1 Young Hee Yoon, MD, PhD, 2 Rubens Belfort, Jr, MD, PhD, 3 Francesco Bandello, 4 Raj K. Maturi, 5 Albert J. Augustin, 6 Xiao Yan Li, 7 Harry Cui, 7 Yehia Hashad, 7 Scott M. Whitcup, MDThe MEAD Study Group Principal Investigators: Suel Abujamra, James Acton, Fareed Ali, Andrew Antoszyk, Albert J. Augustin, Carl C. Awh, Adiel Barak, Karl Ulrich Bartz Schmidt, Caroline R. Baumal, Rubens Belfort, J.r., Muna Bhende, William Z. Bridges, David M. Brown, Trevor Carmichael, Ken Carnevale, Antonio M. Casella, Tom Chang, Daniel Chechik, San Ni Chen, Lawrence P. Chong, Victor Chong, Joel Corwin, Catherine Creuzot Garcher, Alan Cruess, Mark Daniell, Marcos P. de Avila, Haroldo Vieira de Moraes, Robert G. Devenyi, Bernard H. Doft, Mark Donaldson, Richard Dreyer, Dean Eliott, Harry M. Engel, Jan Ernest, Thomas F. Essman, Philip M. Falcone, Sharon Fekrat, Joseph R. Ferencz, Joao L. Ferreira, Joao Figueira, Ivan Fiser, Bradley Foster, Gregory M. Fox, William R. Freeman, S. P. Garg, Mark Gillies, David Glaser, Burton G. Goldstein, Andre M. V. Gomes, John R. Gonder, Lingam Gopal, Petrus Gous, Amod Gupta, Anurag Gupta, Lawrence Halperin, Dennis Han, Seenu M. Hariprasad, Frank G. Holz, Peter Kaiser, Bohdana Kalvodova, Barrett Katz, Randy S. Katz, Dariusz Kecik, Judianne Kellaway, Itamar Klemperer, Baruch Kuppermann, Paolo Lanzetta, Rosangela Lattanzio, Won Ki Lee, John Lehr, Monique Leys, Isaac Loose, Andrew Lotery, Da Wen Lu, Paul McCartney, Ajit B. Majji, Jose A. Martinez, Pascale Massin, Raj K. Maturi, Ugo Menchini, Geeta Menon, Mark Michels, Edoardo Midena, James Miller, Paul Mitchell, Joseph Moisseiev, Lawrence Morse, Rafael Navarro, Janos Nemeth, Henry Newland, Richard Newsom, John Nichols, Juan Orellana, Nicola Orzalesi, Augusto Paranhos, Robert Park, Susanna Park, Maurizio Battaglia Parodi, Peter R. Pavan, James Peace, Don J. Perez Ortiz, Ayala Pollack, Kim Ramaswamy, Ramakrishna Ratnakaram, Giuseppe Ravalico, Jiri Rehak, Kourous Rezaei, Stanislao Rizzo, Francisco J. Rodriguez Alvira, Jean Paul Romanet, Steven Rose, Richard B. Rosen, Luca Rossetti, Jose Maria Ruiz Moreno, SriniVas Sadda, Kenneth Sall, Dirk Sandner, Alvaro Fernandez Vega Sanz, Gil Sartani, Stefanie Schmickler, Steven D. Schwartz, Y. R. Sharma, Shwu Jiuan Sheu, Michael Singer, Sobha Sivaprasad, Gisele Soubrane, Petr Soucek, Eric H. Souied, Giovanni Staurenghi, Jan Studnicka, Marta Suarez Figueroa, Walter Y. Takahashi, Patrick L. Tsai, Lawrence J. Ulanski, Harvey Uy, Monica Varano, Miroslav Veith, Igor Vicha, Francesco Viola, Linda Visser, Dov Weinberger, Glenn L. Wing, Edmund Wong, Tien Wong, Edward Wylegala, Jiong Yan, Young Hee Yoon, Lucy H. Young, Hyeong G. Yu, Ingrid E. Zimmer Galler, TOGNETTO, DANIELE

Publikováno v: Ozurdex MEAD Study Group & Newsom, R B 2014, ' Three-year, randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with diabetic macular edema ', Ophthalmology, vol. 121, no. 10, pp. 1904-1914 . https://doi.org/10.1016/j.ophtha.2014.04.024

Purpose: To evaluate the safety and efficacy of dexamethasone intravitreal implant (Ozurdex, DEX implant) 0.7 and 0.35 mg in the treatment of patients with diabetic macular edema (DME).Design: Two randomized, multicenter, masked, sham-controlled, pha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac6868a174f5dad2c622dd901451a00
https://doi.org/10.1016/j.ophtha.2014.04.024

Anatomical effects of dexamethasone intravitreal implant in diabetic macular oedema: a pooled analysis of 3-year phase III trials

Autor: Srinivas R. Sadda, Ronald P. Danis, Xiao-yan Li, Yehia Hashad, Harry Cui, Scott M. Whitcup

Publikováno v: The British Journal of Ophthalmology

Background/aim To assess long-term effects of dexamethasone intravitreal implant (DEX implant) monotherapy on retinal morphology in diabetic macular oedema (DME). Methods Two multicentre, masked, phase III studies with identical protocols randomised

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4534da1b2f9c09c8c2b2b6d2d6fc4ad0
https://doi.org/10.1136/bjophthalmol-2015-306823

Battery Prognostics: SoC and SoH Prediction

Autor: Jun Ni, Harry Cui, Mohammad Rezvanizaniani, Seung-Chul Lee

Publikováno v: ASME 2012 International Manufacturing Science and Engineering Conference.

Battery applications (computer, cell phones or even in cars) have been extensively used in our daily life. The reasons for their success and extensive usage in the real world applications are their light weight, smaller sizes and greater energy densi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c8f79a37e70b6daad3aa729d5b75fcbe
https://doi.org/10.1115/msec2012-7345

Celecoxib effectively treats patients with acute shoulder tendinitis/bursitis

Autor: Michelle, Petri, Stephen L, Hufman, Gregory, Waser, Harry, Cui, Michael C, Snabes, Kenneth M, Verburg

Publikováno v: The Journal of rheumatology. 31(8)

Shoulder tendinitis and subacromial bursitis are acute, painful inflammatory musculoskeletal conditions that may recur as a result of overuse. We investigated the efficacy of celecoxib in managing patients with acute shoulder tendinitis/bursitis.In t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ddeeb598c038f82122e2e2c91e054cd3
https://pubmed.ncbi.nlm.nih.gov/15290743

Dexamethasone Intravitreal Implant for Noninfectious Intermediate or Posterior Uveitis.

Autor: Lowder, Careen, Belfort, Jr., Rubens, Lightman, Sue, Foster, C. Stephen, Robinson, Michael R., Schiffman, Rhett M., Xiao-Yan Li, Harry Cui, Whitcup, Scott M.

Publikováno v: Archives of Ophthalmology; May2011, Vol. 129 Issue 5, p545-553, 9p