Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Harry Cheuk Hay, Lau"'
Autor:
Yang Song, Wei Zhong, Harry Cheuk-Hay Lau, Yating Zhang, Huayu Guan, Mingxu Xie, Suki Ha, Diwen Shou, Yongjian Zhou, Hongzhi Xu, Jun Yu, Xiang Zhang
Publikováno v:
Engineering, Vol 41, Iss , Pp 204-215 (2024)
Carboxyl ester lipase (CEL), a pivotal enzyme involved in lipid metabolism, is recurrently mutated in obese mice. Here, we aimed to elucidate the functional significance, molecular mechanism, and therapeutic potential of CEL in metabolic dysfunction-
Externí odkaz:
https://doaj.org/article/cee61af6a9e2452aa805d19c15d00b50
Publikováno v:
Pharmacological Research, Vol 208, Iss , Pp 107373- (2024)
Gastrointestinal cancer is a worldwide health challenge due to its dramatically increasing prevalence and as a leading cause of cancer-related mortality. Increasing evidence has illustrated the vital role of gut microbes-derived metabolites in gastro
Externí odkaz:
https://doaj.org/article/4b4a2dd2ee2643b6877f937d0c90880b
Autor:
Xianyi Zeng, Xiang Zhang, Hao Su, Hongyan Gou, Harry Cheuk-Hay Lau, Xiaoxu Hu, Ziheng Huang, Yan Li, Jun Yu
Publikováno v:
Engineering, Vol 35, Iss , Pp 257-269 (2024)
Non-alcoholic steatohepatitis (NASH) is a severe form of non-alcoholic fatty liver disease without effective treatment. The traditional Chinese medicine formulation Pien Tze Huang (PTH) can suppress inflammatory diseases. Here, we evaluate the effect
Externí odkaz:
https://doaj.org/article/4a431b3dfc754b0683a4ae03b8041cb7
Autor:
Jun-Jun She, Wei-Xin Liu, Xiao-Ming Ding, Gang Guo, Jing Han, Fei-Yu Shi, Harry Cheuk-Hay Lau, Chen-Guang Ding, Wu-Jun Xue, Wen Shi, Gai-Xia Liu, Zhe Zhang, Chen-Hao Hu, Yinnan Chen, Chi Chun Wong, Jun Yu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The microbiome in a specific human organ has been well-studied, but few reports have investigated the multi-organ microbiome as a whole. Here, we aim to analyse the intra-individual inter-organ and intra-organ microbiome in deceased humans.
Externí odkaz:
https://doaj.org/article/4cc4e1302c3142bfbc633c790c971e94
Autor:
Harry Cheuk-Hay Lau, Xiang Zhang, Fenfen Ji, Yufeng Lin, Wei Liang, Qing Li, Danyu Chen, Winnie Fong, Xing Kang, Weixin Liu, Eagle Siu-Hong Chu, Queena Wing-Yin Ng, Jun Yu
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104952- (2024)
Summary: Background: Gut probiotic depletion is associated with non-alcoholic fatty liver disease-associated hepatocellular carcinoma (NAFLD-HCC). Here, we investigated the prophylactic potential of Lactobacillus acidophilus against NAFLD-HCC. Method
Externí odkaz:
https://doaj.org/article/d1a496c71a364cbb9bf0c5d16230342a
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTTrillions of microbes are indigenous to the human gastrointestinal tract, together forming an ecological community known as the gut microbiota. The gut microbiota is involved in dietary digestion to produce various metabolites. In healthy con
Externí odkaz:
https://doaj.org/article/d404940a81c04e44b49932023b57ed78
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 21, Iss 1, Pp 84-96 (2023)
Colorectal cancer (CRC) is one of the most frequently diagnosed cancers and the leading cause of cancer-associated deaths. Epidemiological studies have shown that both genetic and environmental risk factors contribute to the development of CRC. Sever
Externí odkaz:
https://doaj.org/article/f493a54f21454edc926d2d64a2b98f3e
Publikováno v:
Chinese Medical Journal, Vol 135, Iss 20, Pp 2395-2397 (2022)
Externí odkaz:
https://doaj.org/article/1a4f7027a9124620ac8097ec2af3cc24
Publikováno v:
Seminars in Cancer Biology. 92:16-27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f5d4a1d53296802086a5a7422d23c40
https://doi.org/10.1016/j.semcancer.2023.03.008
https://doi.org/10.1016/j.semcancer.2023.03.008
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1710 (2022)
Colorectal cancer (CRC) is a malignant disease that is the second most common cancer worldwide. CRC arises from the complex interactions among a variety of genetic and environmental factors. To understand the mechanism of colon tumorigenesis, preclin
Externí odkaz:
https://doaj.org/article/b42c3801614d4df7a0441f62724c21bf