Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Harry C. Hwang"'
Autor:
Daniel A Kuppers, Harry C Hwang, Aimee L Jackson, Peter S Linsley, Bruce E Clurman, Matthew L Fero
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e14758 (2011)
Mice lacking the p27(Kip1) Cdk inhibitor (Cdkn1b) exhibit increased susceptibility to lymphomas from the Maloney murine leukemia virus (M-MuLV), and exhibit a high frequency of viral integrations at Xpcl1 (Kis2), a locus on the X-chromosome. Xpcl1 en
Externí odkaz:
https://doaj.org/article/d72def821bff4b12b228cd374b202ed2
Autor:
Carrie M Garrett-Engele, Michael A Tasch, Harry C Hwang, Matthew L Fero, Roger M Perlmutter, Bruce E Clurman, James M Roberts
Publikováno v:
PLoS Genetics, Vol 3, Iss 12, p e219 (2007)
The cyclin-dependent kinase inhibitor p27(KIP1) is a tumor suppressor gene in mice, and loss of p27 protein is a negative prognostic indicator in human cancers. Unlike other tumor suppressors, the p27 gene is rarely mutated in tumors. Therefore misre
Externí odkaz:
https://doaj.org/article/3c113f238bd94d4da9eb5f2d05bb5853
Autor:
Harry C. Hwang, Daniel A. Kuppers, Lavanya Samraj, Matthew L. Fero, Thomas M. Schmitt, Bruce E. Clurman
Publikováno v:
Oncotarget
// Daniel A. Kuppers 1 , Thomas M. Schmitt 1 , Harry C. Hwang 2 , Lavanya Samraj 3 , Bruce E. Clurman 1 and Matthew L. Fero 4 1 Fred Hutchinson Cancer Research Center, Seattle, Washington, USA 2 Phenopath Laboratories, Seattle, Washington, USA 3 Univ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca8ccc734b9b7019f85f06ba1cbc69e7
https://doi.org/10.18632/oncotarget.16932
https://doi.org/10.18632/oncotarget.16932
Autor:
Harry C. Hwang, Stephanie Rodriguez, April Carr, Ashlie Cindric, Allen M. Gown, Carmen Michelsen, Andrew Churg, Christopher C.H. Tse, Shawna Pyott, Kim D. Thompson
Publikováno v:
The American journal of surgical pathology. 40(5)
The separation of sarcomatous and desmoplastic mesotheliomas from benign organizing pleuritis can be morphologically very difficult. Deletion of p16 (CDKN2A) by fluorescence in situ hybridization (FISH) testing appears to be a reliable marker of mali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2850fd2f508e20b809a4f5bb9319c6
https://pubmed.ncbi.nlm.nih.gov/26900815
https://pubmed.ncbi.nlm.nih.gov/26900815
Autor:
Harry C, Hwang, Allen M, Gown
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1406
Current standard of care requires that HER2 gene testing be performed on all newly diagnosed invasive breast cancers in order to determine eligibility for anti-HER2 antibody therapy and should be performed in accordance with current ASCO-CAP guidelin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2200bf4db29f2d9de6661b5b23fdf060
https://pubmed.ncbi.nlm.nih.gov/26820945
https://pubmed.ncbi.nlm.nih.gov/26820945
Autor:
Harry C. Hwang, Allen M. Gown
Publikováno v:
Methods in Molecular Biology ISBN: 9781493934423
Current standard of care requires that HER2 gene testing be performed on all newly diagnosed invasive breast cancers in order to determine eligibility for anti-HER2 antibody therapy and should be performed in accordance with current ASCO-CAP guidelin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14822f7489460afd7ec49dc35a75d09d
https://doi.org/10.1007/978-1-4939-3444-7_5
https://doi.org/10.1007/978-1-4939-3444-7_5
Publikováno v:
Cancer Research. 72:P1-07
Background: The 2007 ASCO-CAP guidelines mandate a high level (95%) of concordance between different testing modalities such as fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) for demonstration of the human epidermal growth f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::970764d56fbe909a453e34e5486c13c4
https://doi.org/10.1158/0008-5472.sabcs12-p1-07-01
https://doi.org/10.1158/0008-5472.sabcs12-p1-07-01
Autor:
Allen M. Gown, Harry C. Hwang, SM Duesterhoeft, SL Kussick, LC Goldstein, CH Tse, PL Kandalaft
Publikováno v:
Cancer Research. 71:P4-09
Background: Detection of HER2 gene amplification by fluorescence in-situ hybridization (FISH) is one of the key tests predicting clinical response of breast cancer to trastuzumab. According to the recent ASCO/CAP guidelines for HER2 testing, the tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc9dff4547f3e40eaea66474526b6821
https://doi.org/10.1158/0008-5472.sabcs11-p4-09-04
https://doi.org/10.1158/0008-5472.sabcs11-p4-09-04
Autor:
Patricia L Kandalaft, Steven J. Kussick, Lynn C. Goldstein, Jesse C. Wiley, Chun Hing Tse, Harry C. Hwang, Allen M. Gown
Publikováno v:
Journal of Clinical Oncology. 29:4168-4174
Purpose The ratio of human epidermal growth factor receptor 2 (HER2) to CEP17 by fluorescent in situ hybridization (FISH) with the centromeric probe CEP17 is used to determine HER2 gene status in breast cancer. Increases in CEP17 copy number have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a46072008947ef7ca9b92f41041e5ea6
https://doi.org/10.1200/jco.2011.36.0107
https://doi.org/10.1200/jco.2011.36.0107
Autor:
Harry C. Hwang, David W. Russell, Michael P. Gustafson, Roli K. Hirata, Amanda Hagar, Markus Welcker, Bruce E. Clurman, Jherek Swanger, Jonathan E. Grim, Johan Ericsson
Publikováno v:
The Journal of Cell Biology
The SCFFBW7 ubiquitin ligase degrades proteins involved in cell division, growth, and differentiation and is commonly mutated in cancers. The Fbw7 locus encodes three protein isoforms that occupy distinct subcellular localizations, suggesting that ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d913b092b30c1701d96f3eac0223f5c
https://doi.org/10.1083/jcb.200802076
https://doi.org/10.1083/jcb.200802076