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of 3
pro vyhledávání: '"Harry A.M. Andree"'
Autor:
Xiao-Xuan Wu, Pojen P. Chen, James J. Hathcock, Harry A.M. Andree, Jacob H. Rand, Douglas J. Taatjes, Anthony W. Ashton, Anthony S. Quinn
Publikováno v:
Blood. 115:2292-2299
Annexin A5 (AnxA5) is a potent anticoagulant protein that crystallizes over phospholipid bilayers (PLBs), blocking their availability for coagulation reactions. Antiphospholipid antibodies disrupt AnxA5 binding, thereby accelerating coagulation react
Autor:
Peter C. Harpel, J. B. A. Ross, Elena Rusinova, Jacob H. Rand, Harry A.M. Andree, C. Calandri, Xiao-Xuan Wu, M. G. Gascon-Lema
Publikováno v:
Blood. 92:1652-1660
The antiphospholipid syndrome is a thrombophilic condition marked by antibodies that recognize anionic phospholipid-protein cofactor complexes. We recently reported that exposure to IgG fractions from antiphospholipid patients reduces the level of an
Autor:
Xiao-Xuan Wu, Jacob H. Rand, Harry A.M. Andree, Jonathan Scher, Seth Guller, Peter C. Harpel, Charles J. Lockwood
Publikováno v:
New England Journal of Medicine. 337:154-160
The mechanisms of vascular thrombosis and pregnancy loss in the antiphospholipid-antibody syndrome are unknown. Levels of annexin V, a phospholipid-binding protein with potent anticoagulant activity, are markedly reduced on placental villi from women