Zobrazeno 1 - 10
of 696
pro vyhledávání: '"Harry, V Vinters"'
Autor:
Hongyan Gu, Chunxu Yang, Issa Al-kharouf, Shino Magaki, Nelli Lakis, Christopher Kazu Williams, Sallam Mohammad Alrosan, Ellie Kate Onstott, Wenzhong Yan, Negar Khanlou, Inma Cobos, Xinhai Robert Zhang, Neda Zarrin-Khameh, Harry V. Vinters, Xiang Anthony Chen, Mohammad Haeri
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-15 (2024)
Abstract Mitosis is a critical criterion for meningioma grading. However, pathologists’ assessment of mitoses is subject to significant inter-observer variation due to challenges in locating mitosis hotspots and accurately detecting mitotic figures
Externí odkaz:
https://doaj.org/article/5b8b379633eb4d5baddc254cb8cd856d
Autor:
Shino Magaki, Ting Zhang, Karam Han, Hilda Mirbaha, William H. Yong, Cristian Achim, Gregory Fishbein, Michael C. Fishbein, Omai Garner, Noriko Salamon, Christopher K. Williams, Miguel A. Valdes-Sueiras, Jeffrey J. Hsu, Theodoros Kelesidis, Glenn E. Mathisen, Helen Lavretsky, Elyse J. Singer, Harry V. Vinters
Publikováno v:
Free Neuropathology, Vol 5 (2024)
Human immunodeficiency virus (HIV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cause significant neurologic disease. Central nervous system (CNS) involvement of HIV has been extensively studied, with well-documented invasion of H
Externí odkaz:
https://doaj.org/article/a9e5e4870c37487da14de5e551e1d468
Autor:
Nicholas Doher, Vahid Davoudi, Shino Magaki, Ryan A. Townley, Mohammad Haeri, Harry V. Vinters
Publikováno v:
Neurology International, Vol 15, Iss 3, Pp 857-867 (2023)
As of 2022, the prevalence of Alzheimer’s disease (AD) among individuals aged 65 and older is estimated to be 6.2 million in the United States. This figure is predicted to grow to 13.8 million by 2060. An accurate assessment of neuropathologic chan
Externí odkaz:
https://doaj.org/article/969fb583e6ea4a1f9527f031a0e9adc5
Autor:
Daniel R. Wong, Shino D. Magaki, Harry V. Vinters, William H. Yong, Edwin S. Monuki, Christopher K. Williams, Alessandra C. Martini, Charles DeCarli, Chris Khacherian, John P. Graff, Brittany N. Dugger, Michael J. Keiser
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-9 (2023)
Abstract Precise, scalable, and quantitative evaluation of whole slide images is crucial in neuropathology. We release a deep learning model for rapid object detection and precise information on the identification, locality, and counts of cored plaqu
Externí odkaz:
https://doaj.org/article/c3d3f3daf1b44aed967015946cc7eb2d
Autor:
Paul M. Seidler, Kevin A. Murray, David R. Boyer, Peng Ge, Michael R. Sawaya, Carolyn J. Hu, Xinyi Cheng, Romany Abskharon, Hope Pan, Michael A. DeTure, Christopher K. Williams, Dennis W. Dickson, Harry V. Vinters, David S. Eisenberg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Evidence suggests that fibrous aggregates of protein tau may be the proximal cause of Alzheimer’s disease. Here, using atomic structures of tau fibrils from brains of people with Alzheimer’s disease, the authors have found small-molecule drug lea
Externí odkaz:
https://doaj.org/article/a6336cf0b0264ed0a047acb9ca2994cf
Autor:
Luminita Ene, Dan Duiculescu, Roxana Radoi, Mihaela Lazar, Gratiela Tardei, Eugenia Ungureanu, Simona Ruta, Harry V. Vinters, Scott Letendre, Igor Grant, Ronald J. Ellis, Cristian L. Achim
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
IntroductionAn unusual cluster of myoclonic epilepsy was observed in a Romanian pediatric HIV cohort concurrent with measles outbreaks. We describe this particular form of subacute measles encephalitis (SME) in a group of HIV-infected children and ad
Externí odkaz:
https://doaj.org/article/dff9b9ad32944c46b35d11f67c5077f1
Autor:
Julia W. Chang, Samuel D. Reyes, Emmanuelle Faure-Kumar, Sandi K. Lam, Michael W. Lawlor, Richard J. Leventer, Sean M. Lew, Paul J. Lockhart, Kathryn Pope, Howard L. Weiner, Noriko Salamon, Harry V. Vinters, Gary W. Mathern, Aria Fallah, Geoffrey C. Owens
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Using a targeted transcriptomics approach, we have analyzed resected brain tissue from a cohort of 53 pediatric epilepsy surgery cases, and have found that there is a spectrum of involvement of both the innate and adaptive immune systems as evidenced
Externí odkaz:
https://doaj.org/article/06fc4d740dee4ce39fe3cd169ded8032
Autor:
Shino Magaki, Zesheng Chen, Alyscia Severance, Christopher K Williams, Ramiro Diaz, Chuo Fang, Negar Khanlou, William H Yong, Annlia Paganini-Hill, Rajesh N Kalaria, Harry V Vinters, Mark Fisher
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 82:333-344
Cerebral microbleeds (CMBs) detected on magnetic resonance imaging are common in patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). The neuropathologic correlates of CMBs are unclear. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e211e35a3f1d95a0499e4f6cb75a6768
https://doi.org/10.1093/jnen/nlad004
https://doi.org/10.1093/jnen/nlad004
Autor:
Shujing Zhang, Ruowei Zhu, Buyan Pan, Hong Xu, Modupe F. Olufemi, Ronald J. Gathagan, Yuanxi Li, Luyan Zhang, Jasmine Zhang, Wenxuan Xiang, Eliot Masahiro Kagan, Xingjun Cao, Chaoxing Yuan, Soo-Jung Kim, Christopher K. Williams, Shino Magaki, Harry V. Vinters, Hilal A. Lashuel, Benjamin A. Garcia, E. James Petersson, John Q. Trojanowski, Virginia M.-Y. Lee, Chao Peng
Publikováno v:
Nature neuroscience, vol 26, iss 2
Cell-to-cell transmission and subsequent amplification of pathological proteins promote neurodegenerative disease progression. Most research on this has focused on pathological protein seeds, but how their normal counterparts, which are converted to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7706c34493fd3dbe9b25fe7c59aed2e
https://doi.org/10.1038/s41593-022-01239-7
https://doi.org/10.1038/s41593-022-01239-7
Autor:
Simon Levinson, Conny H. Tran, Joshua Barry, Brett Viker, Michael S. Levine, Harry V. Vinters, Gary W. Mathern, Carlos Cepeda
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
In the present study, we characterized the effects of bath application of the proconvulsant drug 4-aminopyridine (4-AP) alone or in combination with GABAA and/or GABAB receptor antagonists, in cortical dysplasia (CD type I and CD type IIa/b), tuberou
Externí odkaz:
https://doaj.org/article/4b1997950ca44d958256466b41bed4c3