Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Harry, Costello"'
Publikováno v:
Cognitive Neuropsychiatry. :1-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80dd140e1f2d544d44d089a7de4007a2
https://doi.org/10.1080/13546805.2023.2212151
https://doi.org/10.1080/13546805.2023.2212151
Publikováno v:
Psychological Medicine. 53:654-667
Depression in dementia is common, disabling and causes significant distress to patients and carers. Despite widespread use of antidepressants for depression in dementia, there is no evidence of therapeutic efficacy, and their use is potentially harmf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e7c3f55c44938cb0ab1dae309cce70
https://doi.org/10.1017/s003329172200397x
https://doi.org/10.1017/s003329172200397x
Publikováno v:
BJPsych Open, Vol 6 (2020)
To date, there have been no detailed reports of patients developing persistent psychotic symptoms following Coronavirus disease 2019 (COVID-19) infection. There have been reports of patients developing transient delirium (with and without hypoxia) af
Externí odkaz:
https://doaj.org/article/31677f4e8c7e4cce88b6d03dfe30d89b
Publikováno v:
BMJ Open, Vol 9, Iss 7 (2019)
Objective Inflammation has been implicated in the aetiology of mental illness. We conducted the first systematic review and meta-analysis of the association between peripheral markers of inflammation and generalised anxiety disorder (GAD).Design Syst
Externí odkaz:
https://doaj.org/article/0de32d02c050438995604dd2a87cc0ef
Apathy is a disabling syndrome associated with poor functional outcomes that is common across a broad range of neurological and psychiatric conditions. Currently there are no established therapies specifically for apathy, and safe and effective treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86bd5e33925cbdbd46275863a8436487
https://doi.org/10.31234/osf.io/m3vjy
https://doi.org/10.31234/osf.io/m3vjy
Publikováno v:
Biological Psychiatry. 93:S246-S247
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5c1f445fd692844ea94591553f1ff03
https://doi.org/10.1016/j.biopsych.2023.02.618
https://doi.org/10.1016/j.biopsych.2023.02.618
Autor:
Rimona Weil, Jonathan Roiser, Eileen Joyce, Robert Howard, Alex Berry, Harry Costello, Suzanne Reeves
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 93:555-562
BackgroundNeuropsychiatric symptoms are common in Parkinson’s disease (PD) and predict poorer outcomes. Reward processing dysfunction is a candidate mechanism for the development of psychiatric symptoms including depression and impulse control diso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c45e0232eef435f643f27b66fc7683
https://doi.org/10.1136/jnnp-2021-327762
https://doi.org/10.1136/jnnp-2021-327762
Autor:
Jonathan Roiser, Robert Howard, Anette Schrag, Harry Costello, Suzanne Reeves, Yumeya Yamamori
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. :jnnp-2022
SummaryBackgroundMotivational symptoms such as apathy and anhedonia are common in Parkinson’s disease, respond poorly to treatment, and have been hypothesised to share underlying neural mechanisms. Striatal dopaminergic dysfunction is considered ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56fdd49fad787ce7de8dde74230648fb
https://doi.org/10.1136/jnnp-2022-330790
https://doi.org/10.1136/jnnp-2022-330790
Autor:
Sanjeev Rajakulendran, Robert D S Pitceathly, Jan-Willem Taanman, Harry Costello, Mary G Sweeney, Cathy E Woodward, Zane Jaunmuktane, Janice L Holton, Thomas S Jacques, Brian N Harding, Carl Fratter, Michael G Hanna, Shamima Rahman
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0145500 (2016)
Mutations in the nuclear gene POLG (encoding the catalytic subunit of DNA polymerase gamma) are an important cause of mitochondrial disease. The most common POLG mutation, A467T, appears to exhibit considerable phenotypic heterogeneity. The mechanism
Externí odkaz:
https://doaj.org/article/ec6375b1818241cab0f1ce4c29b4eb0c
Autor:
Suzanne Reeves, Harry Costello, Kathy Y. Liu, Robert Howard, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
J Alzheimers Dis
Background: Agitation in Alzheimer’s disease (AD) has been hypothesized to be an expression of anxiety, but whether anxiety early in the course of dementia could be a risk factor for developing later agitation is unknown. Objective: We used the Alz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1d0680114e8b389f5e1d532c5f4b43
https://doi.org/10.3233/jad-200516
https://doi.org/10.3233/jad-200516