Výsledky vyhledávání - "Harrison-Moench E"

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Evobrutinib, a covalent Bruton's tyrosine kinase inhibitor: Mass balance, elimination route, and metabolism in healthy participants.

Autor: Scheible H; The healthcare business of Merck KGaA, Darmstadt, Germany., Dyroff M; EMD Serono, Billerica, Massachusetts, USA., Seithel-Keuth A; The healthcare business of Merck KGaA, Darmstadt, Germany., Harrison-Moench E; The healthcare business of Merck KGaA, Darmstadt, Germany., Mammasse N; Cytel Inc, Paris, France., Port A; The healthcare business of Merck KGaA, Darmstadt, Germany., Bachmann A; The healthcare business of Merck KGaA, Darmstadt, Germany., Dong J; EMD Serono, Billerica, Massachusetts, USA., van Lier JJ; PRA Health Sciences, Groningen, The Netherlands., Tracewell W; Nuventra Inc, Exton, Pennsylvania, USA., Mitchell D; Nuventra Inc, Exton, Pennsylvania, USA.

Publikováno v: Clinical and translational science [Clin Transl Sci] 2021 Nov; Vol. 14 (6), pp. 2420-2430. Date of Electronic Publication: 2021 Aug 10.

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Demonstration of physicochemical and functional similarity between Stimufend (pegfilgrastim-fpgk) and Neulasta (pegfilgrastim): A comparative analytical assessment.

Autor: Sykes, Alison¹ (AUTHOR), Ingram, Louise¹ (AUTHOR), Kronthaler, Ulrich¹ (AUTHOR), Chevalet, Laurent¹ (AUTHOR) laurent.chevalet@fresenius-kabi.com

Publikováno v: PLoS ONE. 10/24/2024, Vol. 19 Issue 10, p1-17. 17p.

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Pharmacokinetics and Pharmacodynamics of a Proposed Pegfilgrastim Biosimilar MSB11455 Versus the Reference Pegfilgrastim Neulasta in Healthy Subjects: A Randomized, Double-blind Trial.

Autor: Lickliter J; Nucleus Network, Melbourne, Australia., Kanceva R; Biosimilars, Fresenius Kabi SwissBioSim, Eysins, Switzerland. Electronic address: Radmila.Kanceva@fresenius-kabi.com., Vincent E; Biosimilars, Fresenius Kabi SwissBioSim, Eysins, Switzerland., Schueler A; Biostatistics, Merck Healthcare, Darmstadt, Germany., Harrison-Moench E; Quantitative Pharmacology, Merck Healthcare, Darmstadt, Germany., Yue CS; Learn and Confirm, Inc., St-Laurent, Québec, Canada., Stahl M; Biosimilars, Fresenius Kabi SwissBioSim, Eysins, Switzerland., Ullmann M; Biosimilars, Fresenius Kabi SwissBioSim, Eysins, Switzerland., Ghori V; Biosimilars, Fresenius Kabi SwissBioSim, Eysins, Switzerland., Griffin P; School of Medicine, University of Queensland, Brisbane, Australia; Department of Medicine and Infectious Diseases, Mater Hospital and Mater Medical Research Institute, Brisbane, Queensland, Australia.

Publikováno v: Clinical therapeutics [Clin Ther] 2020 Aug; Vol. 42 (8), pp. 1508-1518.e1. Date of Electronic Publication: 2020 Jul 11.

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Akademický článek

Relative Bioavailability of Orally Dispersible Tablet Formulations of Levo- and Racemic Praziquantel: Two Phase I Studies.

Autor: Bagchus WM; Quantitative Pharmacology, Merck Institute for Pharmacometrics (an affiliate of Merck KGaA, Darmstadt, Germany), Lausanne, Switzerland., Bezuidenhout D; Merck KGaA, Modderfontein, South Africa., Harrison-Moench E; Quantitative Pharmacology, Merck KGaA, Darmstadt, Germany., Kourany-Lefoll E; Global Health Institute, Ares Trading S.A., Coinsins, Switzerland., Wolna P; Global Biostatistics, Merck KGaA, Darmstadt, Germany., Yalkinoglu O; Quantitative Pharmacology, Merck KGaA, Darmstadt, Germany.

Publikováno v: Clinical and translational science [Clin Transl Sci] 2019 Jan; Vol. 12 (1), pp. 66-76. Date of Electronic Publication: 2018 Dec 21.

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Praziquantel Fifty Years on: A Comprehensive Overview of Its Solid State †.

Autor: D'Abbrunzo, Ilenia¹ (AUTHOR) gprocida@units.it, Procida, Giuseppe¹ (AUTHOR), Perissutti, Beatrice¹ (AUTHOR) bperissutti@units.it

Publikováno v: Pharmaceutics. Jan2024, Vol. 16 Issue 1, p27. 38p.

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Evobrutinib pathway to its major metabolite M463-2 and insights from a biotransformation and DDI perspective.

Autor: Scheible, Holger¹ holger.scheible@merckgroup.com, Schieferstein, Hanno¹, Schmidt, Ralf², Pusecker, Klaus¹, Gradhand, Ulrike¹, Gopalakrishnan, Sathej³, Iqbal, Khalid³, Dong, Jennifer², Jones, Reinaldo², Meli, Claudia⁴, Bolleddula, Jayaprakasam², Dyroff, Martin², Georgi, Katrin¹

Publikováno v: Xenobiotica. 2023, Vol. 53 Issue 8/9, p547-558. 12p.

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Drugs for neglected tropical diseases: availability of age-appropriate oral formulations for young children.

Autor: Al-Obaidi, Issraa¹ (AUTHOR), Krome, Anna K.² (AUTHOR), Wagner, Karl G.² (AUTHOR), Pfarr, Kenneth^3,4 (AUTHOR), Kuesel, Annette C.⁵ (AUTHOR), Batchelor, Hannah K.¹ (AUTHOR) Hannah.batchelor@strath.ac.uk

Publikováno v: Parasites & Vectors. 12/12/2022, Vol. 15 Issue 1, p1-22. 22p.

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Revisiting the Dissolution of Praziquantel in Biorelevant Media and the Impact of Digestion of Milk on Drug Dissolution.

Autor: Eason, Thomas¹ (AUTHOR), Ramirez, Gisela¹ (AUTHOR), Clulow, Andrew J.^1,2 (AUTHOR), Salim, Malinda¹ (AUTHOR), Boyd, Ben J.^1,3 (AUTHOR) ben.boyd@monash.edu

Publikováno v: Pharmaceutics. Oct2022, Vol. 14 Issue 10, pN.PAG-N.PAG. 11p.

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