Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Harrison Paret"'
Autor:
Guermarie Velazquez-Torres, Einav Shoshan, Cristina Ivan, Li Huang, Enrique Fuentes-Mattei, Harrison Paret, Sun Jin Kim, Cristian Rodriguez-Aguayo, Victoria Xie, Denise Brooks, Steven J. M. Jones, A. Gordon Robertson, George Calin, Gabriel Lopez-Berenstein, Anil Sood, Menashe Bar-Eli
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
In melanoma, reduced ADAR1 impairs A-to-I microRNA editing. Here, the authors show that miR-378a-3p undergoes this editing in non-metastatic cells and the edited form of miR-378a-3p binds to the PARVA oncogene, inhibiting its expression and preventin
Externí odkaz:
https://doaj.org/article/dd20c2509c0c46dbbe02e75f436eee1a
Autor:
Cristina Ivan, A. Gordon Robertson, Victoria K. Xie, Gabriel Lopez-Berenstein, Guermarie Velazquez-Torres, Li Huang, Einav Shoshan, Anil K. Sood, Harrison Paret, George A. Calin, Menashe Bar-Eli, Sun Jin Kim, Steven J.M. Jones, Enrique Fuentes-Mattei, Cristian Rodriguez-Aguayo, Denise Brooks
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Previously we have reported that metastatic melanoma cell lines and tumor specimens have reduced expression of ADAR1 and consequently are impaired in their ability to perform A-to-I microRNA (miRNA) editing. The effects of A-to-I miRNAs editing on me