Výsledky vyhledávání - "Harrison McAdams"

Reflexive Eye Closure in Response to Cone and Melanopsin Stimulation: A Study of Implicit Measures of Light Sensitivity in Migraine

Autor: Edda B Haggerty, Geoffrey K. Aguirre, Eric A. Kaiser, Harrison McAdams, Brett Cucchiara, David H. Brainard, Aleksandra Igdalova

Publikováno v: Neurology

Background and ObjectivesTo quantify interictal photophobia in migraine with and without aura using reflexive eye closure as an implicit measure of light sensitivity and to assess the contribution of melanopsin and cone signals to these responses.Met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08170fccfae6d2de49f6b6fb25a36efd
https://pubmed.ncbi.nlm.nih.gov/34493620

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Enhanced reflexive eye closure is mediated by ipRGC signals and is specific to migraine with visual aura

Autor: Edda B Haggerty, Eric A. Kaiser, Brett Cucchiara, Geoffrey K. Aguirre, David H. Brainard, Aleksandra Igdalova, Harrison McAdams

ObjectiveTo assess the contribution of the melanopsin-containing, intrinsically photosensitive retinal ganglion cells (ipRGCs) and the cones to reflexive eye closure as an implicit measure of interictal photophobia in migraine.MethodsWe studied twent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e84304c6777de7ea5e4ea29b6851ddf
https://doi.org/10.1101/2020.12.12.422528

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Selective amplification of ipRGC signals accounts for interictal photophobia in migraine

Autor: Edda B Haggerty, David H. Brainard, Geoffrey K. Aguirre, Harrison McAdams, Brett Cucchiara, Aleksandra Igdalova, Eric A. Kaiser

Publikováno v: Proc Natl Acad Sci U S A

Second only to headache, photophobia is the most debilitating symptom reported by people with migraine. While the melanopsin-containing, intrinsically photosensitive retinal ganglion cells (ipRGCs) are thought to play a role, how cone and melanopsin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4beea504f0c1afa7acfffbf128a2cdc9
https://doi.org/10.1101/2020.04.17.047290

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Attenuated resting-state functional connectivity in patients with childhood- and adult-onset schizophrenia

Autor: Liv S. Clasen, Stephen J. Gotts, Rebecca E. Watsky, Xueping Zhou, Anna E. Ordóñez, M Deanna, Peter Gochman, Siyuan Liu, Dede Greenstein, Rebecca A. Berman, Francois Lalonde, Lorie Shora, Alex Martin, Harrison McAdams, Judith L. Rapoport, Nitin Gogtay

Publikováno v: Schizophrenia Research. 197:219-225

Childhood-onset schizophrenia (COS) is a rare, severe form of the adult-onset disorder (AOS). Our previous resting-state fMRI study identified attenuated functional connectivity in COS compared with controls. Here, we ask whether COS and AOS patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b6a213089c173df1a28ffb2e0cb7e9
https://doi.org/10.1016/j.schres.2018.01.003

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Pulses of melanopsin-directed contrast produce highly reproducible pupilresponses that are insensitive to a change in background radiance

Autor: Manuel Spitschan, Aleksandra Igdalova, Geoffrey K. Aguirre, Harrison McAdams, David H. Brainard

PurposeTo measure the pupil response to pulses of melanopsin-directed contrast, and compare this response to those evoked by cone-directed contrast and spectrally-narrowband stimuli.Methods3-second unipolar pulses were used to elicit pupil responses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14eb0b5663e4973eb21f0bc6a172b8df
https://doi.org/10.1101/365718

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Pulses of Melanopsin-Directed Contrast Produce Highly Reproducible Pupil Responses That Are Insensitive to a Change in Background Radiance

Autor: Aleksandra Igdalova, David H. Brainard, Manuel Spitschan, Geoffrey K. Aguirre, Harrison McAdams

Publikováno v: Investigative Ophthalmology and Visual Science
Investigative Ophthalmology & Visual Science

Purpose: To measure the pupil response to pulses of melanopsin-directed contrast, and compare this response to those evoked by cone-directed contrast and spectrally narrowband stimuli. Methods: Three-second unipolar pulses were used to elicit pupil r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f04a4d386a1829be515511302e544a
https://doi.org/10.1167/iovs.18-25219

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Delayed Development of Brain Connectivity in Adolescents With Schizophrenia and Their Unaffected Siblings

Autor: Luca Cocchi, Liv S. Clasen, Alex Fornito, Judith L. Rapoport, Deanna Greenstein, Harrison McAdams, Nitin Gogtay, Christos Pantelis, Andrew Zalesky, Vanessa Cropley

Publikováno v: JAMA psychiatry. 72(9)

Abnormalities in structural brain connectivity have been observed in patients with schizophrenia. Mapping these abnormalities longitudinally and understanding their genetic risk via sibship studies will provide crucial insight into progressive develo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd0420631a05861a03cba881f144903
https://pubmed.ncbi.nlm.nih.gov/26176634

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