Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Harrison M. Penrose"'
Autor:
Rida Iftikhar, Harrison M. Penrose, Angelle N. King, Joshua S. Samudre, Morgan E. Collins, Alifiani B. Hartono, Sean B. Lee, Frank Lau, Melody Baddoo, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic
Publikováno v:
Oncogenesis, Vol 10, Iss 11, Pp 1-10 (2021)
Abstract Obesity is a worldwide epidemic associated with increased risk and progression of colon cancer. Here, we aimed to determine the role of adipose triglyceride lipase (ATGL), responsible for intracellular lipid droplet (LD) utilization, in obes
Externí odkaz:
https://doaj.org/article/dad0fa3c4c914a0ebba7e45d5f2c7f93
Autor:
Harrison M. Penrose, Rida Iftikhar, Morgan E. Collins, Eman Toraih, Emmanuelle Ruiz, Nathan Ungerleider, Hani Nakhoul, Erik F. Flemington, Emad Kandil, Shamita B. Shah, Suzana D. Savkovic
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The heterogeneous pathobiology underlying Ulcerative Colitis (UC) is not fully understood. Using publicly available transcriptomes from adult UC patients, we identified the immune cell landscape, molecular pathways, and differentially expres
Externí odkaz:
https://doaj.org/article/e760a94f0fe148a6a82d2a1f02490469
Autor:
Young Su Park, Sang Bum Kang, Ronald R. Marchelletta, Harrison M. Penrose, Roos Ruiter-Visser, Barbara Jung, Michael J. Docherty, Brigid S. Boland, William J. Sandborn, Declan F. McCole
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 811 (2023)
The prostone analog, lubiprostone, is approved to manage constipation-predominant irritable bowel syndrome. Lubiprostone also protects intestinal mucosal barrier function in animal models of colitis. The aim of this study was to determine if lubipros
Externí odkaz:
https://doaj.org/article/5f068f2b880b4b1ab6c054eb34c860c1
Autor:
Emmanuelle Ruiz, Harrison M. Penrose, Sandra Heller, Hani Nakhoul, Melody Baddoo, Erik F. Flemington, Emad Kandil, Suzana D. Savkovic
Publikováno v:
Gut Microbes, Vol 11, Iss 3, Pp 350-363 (2020)
Inflammatory bowel disease (IBD) has been linked to active signaling with bacterial components and reduced mitochondrial ATP production; however, synergism between both of these disease characteristics remains unclear. We aimed to determine in human
Externí odkaz:
https://doaj.org/article/15355e26874241f1bf6b0de62ccbd1f3
Autor:
Harrison M. Penrose, Chloe Cable, Sandra Heller, Nathan Ungerleider, Hani Nakhoul, Melody Baddoo, Alifiani B. Hartono, Sean B. Lee, Matthew E. Burow, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 2, Pp 391-408 (2019)
Background & Aims: Diminished forkhead box O3 (FOXO3) function drives inflammation and cancer growth; however, mechanisms fostering these pathobiologies are unclear. Here, we aimed to identify in colon loss of FOXO3-dependent cellular and molecular c
Externí odkaz:
https://doaj.org/article/7337e8aa807f4d11a94daa9ce23793f7
Autor:
Rida Iftikhar, Harrison M. Penrose, Angelle N. King, Joshua S. Samudre, Morgan E. Collins, Alifiani B. Hartono, Sean B. Lee, Frank Lau, Melody Baddoo, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/df3e440f84514614aa5dd372b8cc26ab
Autor:
Rida Iftikhar, Harrison M. Penrose, Angelle N. King, Yunah Kim, Emmanuelle Ruiz, Emad Kandil, Heather L. Machado, Suzana D. Savkovic
Publikováno v:
Metabolites, Vol 12, Iss 3, p 250 (2022)
Obesity, characterized by augmented inflammation and tumorigenesis, is linked to genetic predispositions, such as FOXO3 polymorphisms. As obesity is associated with aberrant macrophages infiltrating different tissues, including the colon, we aimed to
Externí odkaz:
https://doaj.org/article/8360caa076894cf0a3351031caf80f12
Autor:
Savkovic, Jenisha Ghimire, Rida Iftikhar, Harrison M. Penrose, Patricia Snarski, Emmanuelle Ruiz, Suzana D.
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9730
Inflammatory bowel disease (IBD), characterized by infiltration of polymorphonuclear neutrophils (PMNs), increases the risk of colon cancer. PMN activation corresponds to the accumulation of intracellular Lipid Droplets (LDs). As increased LDs are ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::0c36404566714041b86fa50434b28cdc
Autor:
Morgan E. Collins, Frank H. Lau, Erik F. Flemington, Suzana D. Savkovic, Harrison M. Penrose, Rida Iftikhar, Alifiani B. Hartono, Sean Bong Lee, Angelle N. King, Susan E. Crawford, Melody Baddoo, Joshua S. Samudre
Publikováno v:
Oncogenesis
Oncogenesis, Vol 10, Iss 11, Pp 1-10 (2021)
Oncogenesis, Vol 10, Iss 11, Pp 1-10 (2021)
Obesity is a worldwide epidemic associated with increased risk and progression of colon cancer. Here, we aimed to determine the role of adipose triglyceride lipase (ATGL), responsible for intracellular lipid droplet (LD) utilization, in obesity-drive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5cf30400829f3e73b4e210e3cd35d2
https://pubmed.ncbi.nlm.nih.gov/35292620
https://pubmed.ncbi.nlm.nih.gov/35292620
Autor:
Emmanuelle Ruiz, Harrison M. Penrose, Emad Kandil, Erik F. Flemington, Suzana D. Savkovic, Hani Nakhoul, Sandra Heller, Melody Baddoo
Publikováno v:
Gut Microbes, Vol 11, Iss 3, Pp 350-363 (2020)
Gut Microbes
Gut Microbes
Inflammatory bowel disease (IBD) has been linked to active signaling with bacterial components and reduced mitochondrial ATP production; however, synergism between both of these disease characteristics remains unclear. We aimed to determine in human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cddde3ff2f32e139544c20ef46529f0
https://doi.org/10.1080/19490976.2019.1611152
https://doi.org/10.1080/19490976.2019.1611152