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An archaic HLA class I receptor allele diversifies natural killer cell-driven immunity in First Nations peoples of Oceania.

Autor: Loh L; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Saunders PM; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Faoro C; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia., Font-Porterias N; Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO 80045, USA., Nemat-Gorgani N; Department of Structural Biology and Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA., Harrison GF; Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO 80045, USA., Sadeeq S; Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO 80045, USA., Hensen L; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Wong SC; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Widjaja J; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Clemens EB; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia., Zhu S; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia., Kichula KM; Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO 80045, USA., Tao S; Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO 80045, USA; Blood Center of Zhejiang Province, Hangzhou, Zhejiang, China., Zhu F; Blood Center of Zhejiang Province, Hangzhou, Zhejiang, China., Montero-Martin G; Stanford Blood Centre, Department of Pathology, Stanford University, Stanford, CA 94305, USA., Fernandez-Vina M; Stanford Blood Centre, Department of Pathology, Stanford University, Stanford, CA 94305, USA., Guethlein LA; Department of Structural Biology and Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA., Vivian JP; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia., Davies J; Menzies School of Health Research, Charles Darwin University, Darwin, NT 0810, Australia; Department of Infectious Diseases, Royal Darwin Hospital, Casuarina, NT 0810, Australia., Mentzer AJ; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7LF, UK., Oppenheimer SJ; Institute of Social and Cultural Anthropology, School of Anthropology and Museum Ethnography, University of Oxford, Oxford OX3 7LF, UK., Pomat W; Papua New Guinea Institute of Medical Research, Post Office Box 60, Goroka, Papua New Guinea., Ioannidis AG; Department of Biomolecular Engineering, UC Santa Cruz, Santa Cruz, CA 95064, USA., Barberena-Jonas C; Advanced Genomics Unit, Center for Research and Advanced Studies (CINVESTAV), Irapuato 36821, Mexico., Moreno-Estrada A; Advanced Genomics Unit, Center for Research and Advanced Studies (CINVESTAV), Irapuato 36821, Mexico., Miller A; Jawun Research Centre, Central Queensland University, Cairns, QLD 4870, Australia., Parham P; Department of Structural Biology and Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA., Rossjohn J; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff CF14 4XN, UK. Electronic address: jamie.rossjohn@monash.edu., Tong SYC; Victorian Infectious Diseases Service, The Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, VIC 3000, Australia; Department of Infectious Diseases, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, VIC 3000, Australia. Electronic address: steven.tong@unimelb.edu.au., Kedzierska K; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia. Electronic address: kkedz@unimelb.edu.au., Brooks AG; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC 3000, Australia. Electronic address: agbrooks@unimelb.edu.au., Norman PJ; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO 80045, USA; Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO 80045, USA; Department of Structural Biology and Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA. Electronic address: paul.norman@cuanschutz.edu.

Publikováno v: Cell [Cell] 2024 Oct 25. Date of Electronic Publication: 2024 Oct 25.