Zobrazeno 1 - 10
of 377
pro vyhledávání: '"Harrison, TS"'
Cryptococcal antigen (CrAg) is detectable in blood prior to the onset of symptomatic cryptococcal meningitis, a leading cause of death among people living with advanced HIV disease globally. Highly sensitive assays can detect CrAg in blood, and scree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::70f9c3ccd66784582ddeaf863f9a149a
https://openaccess.sgul.ac.uk/id/eprint/114736/1/ciac675.pdf
https://openaccess.sgul.ac.uk/id/eprint/114736/1/ciac675.pdf
Autor:
Jiang, Y-K, Wang, R-Y, Zhou, L-H, Cheng, J-H, Luo, Y, Zhu, R-S, Qiu, W-J, Zhao, H-Z, Wang, X, Harrison, TS, Zhu, L-P
The cerebrospinal fluid (CSF) immune responses in HIV-uninfected cryptococcal meningitis (CM) have not been well studied. In this study, we aimed to explore the phenotype of CSF immune response during the course of disease and to examine relationship
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::869d3956d7398ec49fa3787790281f6c
https://openaccess.sgul.ac.uk/id/eprint/114829/1/fimmu-13-993495.pdf
https://openaccess.sgul.ac.uk/id/eprint/114829/1/fimmu-13-993495.pdf
Autor:
Yoon, H, Wake, RM, Nakouzi, AS, Wang, T, Agalliu, I, Tiemessen, CT, Govender, NP, Jarvis, JN, Harrison, TS, Pirofski, LA
BACKGROUND: Asymptomatic cryptococcal antigenemia (positive blood cryptococcal antigen [CrAg]) is associated with increased mortality in HIV-positive individuals even after adjusting for CD4 count and despite receiving antifungal treatment. The assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::9988316177084c4916175dd375119268
https://openaccess.sgul.ac.uk/id/eprint/114656/1/ciac633.pdf
https://openaccess.sgul.ac.uk/id/eprint/114656/1/ciac633.pdf
Cryptococcal meningitis is the leading cause of adult meningitis in patients with HIV, and accounts for 15% of all HIV-related deaths in sub-Saharan Africa. The mainstay of management is effective antifungal therapy, despite a limited arsenal of anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::10ab371cf2cbd08697dbddf136cfae53
Autor:
Stott, KE, Loyse, A, Jarvis, JN, Alufandika, M, Harrison, TS, Mwandumba, HC, Day, JN, Lalloo, DG, Bicanic, T, Perfect, JR, Hope, W
Cryptococcal meningoencephalitis was first described over a century ago. This fungal infection is preventable and treatable yet continues to be associated with excessive morbidity and mortality. The largest burden of disease resides in people living
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b14611251d3eb126443ebe48728a4309
Autor:
Temfack, E, Rim, JJB, Spijker, R, Loyse, A, Chiller, T, Pappas, PG, Perfect, J, Sorell, TC, Harrison, TS, Cohen, JF, Lortholary, O
Cryptococcal antigen (CrAg) detection could direct timely initiation of antifungal therapy. We searched MEDLINE and EMBASE for studies where CrAg detection in serum/cerebrospinal fluid (CSF) and CSF fungal culture were done on HIV-positive adults wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::96017f75341a38c07a818191a0ee19f3
https://openaccess.sgul.ac.uk/id/eprint/112539/1/ciaa1243.pdf
https://openaccess.sgul.ac.uk/id/eprint/112539/1/ciaa1243.pdf
Autor:
Tenforde, MW, Boyer-Chammard, T, Muthoga, C, Tawe, L, Milton, T, Rulaganyang, I, Lechiile, K, Rukasha, I, Leeme, TB, Govender, NP, Ngidi, J, Mine, M, Molloy, SF, Harrison, TS, Lortholary, O, Jarvis, JN
High cryptococcal antigen (CrAg) titers in blood are associated with subclinical meningitis and mortality in CrAg-positive individuals with advanced HIV disease (AHD). We evaluated a novel semiquantitative lateral flow assay (LFA), CryptoPS, that may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::23c761214ebf45455508397df16e77a6
https://researchonline.lshtm.ac.uk/id/eprint/4661272/1/JCM.02307-20.pdf
https://researchonline.lshtm.ac.uk/id/eprint/4661272/1/JCM.02307-20.pdf
Autor:
Chen, T, Mwenge, L, Lakhi, S, Chanda, D, Mwaba, P, Molloy, SF, Gheorghe, A, Griffiths, UK, Heyderman, RS, Kanyama, C, Kouanfack, C, Mfinanga, S, Chan, AK, Temfack, E, Kivuyo, S, Hosseinipour, MC, Lortholary, O, Loyse, A, Jaffar, S, Harrison, TS, Niessen, LW, ACTA Trial Team
Background\ud Mortality from cryptoccocal meningitis remains high. The ACTA trial demonstrated that, compared with 2 weeks of amphotericin B (AmB) plus flucystosine (5FC), 1 week of AmB and 5FC was associated with lower mortality and 2 weeks of oral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::ac8abe6ccc1d99ff9013e3820aedad89
https://openaccess.sgul.ac.uk/id/eprint/110685/6/ciy971.pdf
https://openaccess.sgul.ac.uk/id/eprint/110685/6/ciy971.pdf
The recent development of highly sensitive and specific point-of-care tests has made it possible to diagnose HIV-associated cryptococcal meningitis within minutes. However, diagnostic advances have not been matched by new antifungal drugs and treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2abfa4e21d2c136e5dc9f6693bc7894d
https://researchonline.lshtm.ac.uk/id/eprint/4653706/1/Recent-advances-in-managing-HIV-associated.pdf
https://researchonline.lshtm.ac.uk/id/eprint/4653706/1/Recent-advances-in-managing-HIV-associated.pdf
Autor:
Zhao, H-Z, Wang, R-Y, Wang, X, Jiang, Y-K, Zhou, L-H, Cheng, J-H, Huang, L-P, Harrison, TS, Zhu, L-P
BACKGROUND: The 2010 Infectious Diseases Society of America (IDSA) guidelines for management of cryptococcal diseases recommend high dose fluconazole (≥ 800 mg/day), either alone or with other antifungal drugs, as alternative anticryptococcal choic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::d6c84dbda6d636665e088d28e658f906
https://openaccess.sgul.ac.uk/id/eprint/110483/1/document.pdf
https://openaccess.sgul.ac.uk/id/eprint/110483/1/document.pdf