Structure-Based Design of Selective and Potent G Quadruplex-Mediated Telomerase Inhibitors

Autor: Read, Martin, Harrison, R. John, Romagnoli, Barbara, Tanious, Farial A., Gowan, Sharon H., Reszka, Anthony P., Wilson, W. David, Kelland, Lloyd R., Neidle, Stephen

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2001 Apr . 98(9), 4844-4849.

Externí odkaz: https://www.jstor.org/stable/3055526

Evaluation of by disubstituted acridone derivatives as telomerase inhibitors: the importance of G-quadruplex binding

Autor: Harrison, R. John, Reszka, Anthony P., Haider, Shozeb M., Romagnoli, Barbara, Morrell, James, Read, Martin A., Gowan, Sharon M., Incles, Christopher M., Kelland, Lloyd R., Neidle, Stephen ^*

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 2004 14(23):5845-5849

Structure-based design of selective and potent G quadruplex-mediated telomarase inhibitors.

Autor: Reed, Martin, Harrison, R. John, Romagnoli, Barbara, Tanious, Farial A., Gowan, Sharon H., Reszka, Anthony P., Wilson, W. David., Kelland, Lloyd R., Neidle, Stephen

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; 04/24/2001, Vol. 98 Issue 9, p4844, 6p, 3 Color Photographs, 2 Diagrams, 4 Charts, 2 Graphs

Trisubstituted acridine derivatives as potent and selective telomerase inhibitors.

Autor: Harrison RJ; Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, 29-39 Brunswick Square, London, WC1N 1AX, U.K., Cuesta J, Chessari G, Read MA, Basra SK, Reszka AP, Morrell J, Gowan SM, Incles CM, Tanious FA, Wilson WD, Kelland LR, Neidle S

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2003 Oct 09; Vol. 46 (21), pp. 4463-76.