ESCRT-0 marks an APPL1-independent transit route for EGFR between the cell surface and the EEA1-positive early endosome

Autor: Flores-Rodriguez, Neftali, Kenwright, David A, Chung, Pei-Hua, Harrison, Andrew W, Stefani, Flavia, Waigh, Thomas A, Allan, Victoria J, Woodman, Philip G

Publikováno v: Flores-Rodriguez, N, Kenwright, D A, Chung, P-H, Harrison, A W, Stefani, F, Waigh, T A, Allan, V J & Woodman, P G 2015, ' ESCRT-0 marks an APPL1-independent transit route for EGFR between the cell surface and the EEA1-positive early endosome. ', Journal of Cell Science, vol. 128, no. 4, pp. 755–767 . https://doi.org/10.1242/jcs.161786

ESCRT-0 sorts ubiquitinated EGFR within the early endosome, so that the receptor can be incorporated into intralumenal vesicles. An important question is whether ESCRT-0 acts solely upon EGFR that has already entered the vacuolar early endosome (char

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3818::1040de95a96785157581bb3d3e2fda05
https://doi.org/10.1242/jcs.161786

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