Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Harris L. Rotman"'
Publikováno v:
The Journal of Immunology. 161:1908-1912
The mechanisms by which Abs mediate protection during blood-stage malaria infections is controversial, with some evidence pointing to the direct effect of Abs on parasite invasion and growth, while other studies suggest that Abs act in cooperation wi
Autor:
Harris L. Rotman, Richard A. Brigandi, Gerhard A. Schad, Wiboonchai Yutanawiboonchai, David Abraham, Thomas J. Nolan, Ofra Leon
Publikováno v:
Experimental Parasitology. 82:279-289
Mice immunized against Strongyloides stercoralis L3 were shown to kill greater than 90% of challenge larvae contained within diffusion chambers. The objective of the present study was to identify the host components responsible for immunity. Serum fr
Publikováno v:
Parasite Immunology. 18:95-102
Immunization of mice with irradiated Onchocerca volvulus infective stage larvae (L3) has been demonstrated to confer protection against challenge infections with these larvae. Additionally, cytokine level measurements and cytokine depletion studies h
Autor:
G.A. Schad, T.J. Nolan, Harris L. Rotman, Wiboonchai Yutanawiboonchai, David Abraham, Ofra Leon, Richard A. Brigandi
Publikováno v:
Experimental Parasitology. 81:136-139
Publikováno v:
Experimental parasitology. 100(3)
At 28 days post-infection autoinfective third-stage larvae (L3a) of Strongyloides stercoralis occurred in jirds infected with 10,000 infective third-stage (L3i). Previously in the jird model of strongyloidiasis, autoinfection had been seen in immunol
Publikováno v:
Experimental parasitology. 91(1)
Rotman, H. L., Daly, T. M., and Long, C. A. 1999.Plasmodium: Immunization with carboxyl-terminal regions of MSP-1 protects against homologous but not heterologous blood-stage parasite challenge.Experimental Parasitology91, 78–85. A leading candidat
Autor:
S. Schnyder-Candrian, Gerhard A. Schad, David Abraham, Harris L. Rotman, T. J. Nolan, Phillip Scott
Publikováno v:
Parasite immunology. 19(1)
The goal of the present study was to determine if immune-mediated killing of S. stercoralis L3 in mice could be modulated by shifting from a Th-2 to a Th-1 type immune response. L3 killing in immunized mice was ablated in CD4+ T cell-depleted animals
Autor:
Wiboonchai Yutanawiboonchai, Gerhard A. Schad, Harris L. Rotman, David Abraham, Gerald J. Gleich, Thomas J. Nolan, Ofra Leon, Richard A. Brigandi
Publikováno v:
Experimental parasitology. 82(3)
Challenge worm survival was significantly reduced when BALB/cByJ mice were vaccinated againstStrongyloides stercoralisinfective third stage larvae (L3) regardless of whether the challenge infections consisted of systemically migrating L3 or L3 implan
Publikováno v:
Parasite immunology. 17(11)
SUMMARY Jirds support the entire life-cycle of Strongyloides stercoralis. We therefore used this host as a model to define the mechanism of the immune response to a challenge infection, as well as the parasite stage effected by the response. Jirds gi
Autor:
Harris L. Rotman, David Abraham, T.J. Nolan, H.F. Haberstroh, G.A. Schad, Wiboonchai Yutanawiboonchai, Ofra Leon, Richard A. Brigandi
Publikováno v:
Experimental parasitology. 80(2)
A murine model system was developed to study the induction and mechanism of protective immunity to L3 of Strongyloides stercoralis. L3 were implanted in BALB/cByJ mice in diffusion chambers constructed with 0.1- or 2.0-microns-pore-size membranes. Pa