Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Harris H. Wang"'
Autor:
Qian Wang, Yicheng Guo, Logan T. Schwanz, Ian A. Mellis, Yiwei Sun, Yiming Qu, Guillaume Urtecho, Riccardo Valdez, Emily Stoneman, Aubree Gordon, Harris H. Wang, David D. Ho, Lihong Liu
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
As SARS-CoV-2 continues to spread and mutate, tracking the viral evolutionary trajectory and understanding the functional consequences of its mutations remain crucial. Here, we characterized the antibody evasion, ACE2 receptor engagement, and viral i
Externí odkaz:
https://doaj.org/article/abf1d75ad25541d9b5a79451cfd5d018
Autor:
Evgeniya Schastnaya, Zrinka Raguz Nakic, Christoph H. Gruber, Peter Francis Doubleday, Aarti Krishnan, Nathan I. Johns, Jimin Park, Harris H. Wang, Uwe Sauer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
While phosphorylation is an essential post-translational modification in eukaryotes only recently the phosphoproteome of prokaryotes has been provided. Here, Schastnaya et al. mutate 52 phosphosites on 23 E. coli enzymes and apply metabolomics to pro
Externí odkaz:
https://doaj.org/article/2160c240cd0443caaf59b15567610f60
Autor:
Christian Munck, Ravi U. Sheth, Edward Cuaresma, Jessica Weidler, Stephania L. Stump, Philip Zachariah, David H. Chong, Anne-Catrin Uhlemann, Julian A. Abrams, Harris H. Wang, Daniel E. Freedberg
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-10 (2020)
Abstract Background The need for early antibiotics in the intensive care unit (ICU) is often balanced against the goal of antibiotic stewardship. Long-course antibiotics increase the burden of antimicrobial resistance within colonizing gut bacteria,
Externí odkaz:
https://doaj.org/article/1f941ee7d7b1477dacd9c6d9879f5091
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Horizontal gene transfer (HGT) in complex bacterial communities has been mostly studied using metagenomic analyses. Here, the authors develop an E. coli CRISPR-Cas spacer acquisition platform that allows real-time recording of HGT events at nucleotid
Externí odkaz:
https://doaj.org/article/f36c8c6e1cf94ca1940242b3347cd40a
Autor:
Daniel E. Freedberg, Miles Richardson, Mary Nattakom, Jacky Cheung, Elissa Lynch, Philip Zachariah, Harris H. Wang
Publikováno v:
mSphere, Vol 7, Iss 1 (2022)
ABSTRACT The gut microbiome of an individual can shape the local environmental surface microbiome. We sought to determine how the intensive care unit (ICU) patient gut microbiome shapes the ICU room surface microbiome, focusing on vancomycin-resistan
Externí odkaz:
https://doaj.org/article/afd3c7b8bfb64df2bbf3eac35a62aff2
Autor:
Jimin Park, Harris H. Wang
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109590- (2021)
Summary: Primary σ70 factors are key conserved bacterial regulatory proteins that interact with regulatory DNA to control gene expression. It is, however, poorly understood whether σ70 sequence diversity in different bacteria reflects functional di
Externí odkaz:
https://doaj.org/article/86fc981d69f14d009571cca6baa16600
Publikováno v:
Nature Methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fdd2d4eb721de31a139e291f3dae9bc
https://doi.org/10.1038/s41592-023-01868-1
https://doi.org/10.1038/s41592-023-01868-1
Autor:
Yiming Huang, Ravi U. Sheth, Shijie Zhao, Lucas A. Cohen, Kendall Dabaghi, Thomas Moody, Yiwei Sun, Deirdre Ricaurte, Miles Richardson, Florencia Velez-Cortes, Tomasz Blazejewski, Andrew Kaufman, Carlotta Ronda, Harris H. Wang
Publikováno v:
Nature Biotechnology.
Pure bacterial cultures remain essential for detailed experimental and mechanistic studies in microbiome research, and traditional methods to isolate individual bacteria from complex microbial ecosystems are labor-intensive, difficult-to-scale and la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39d4e157678b3fc496b40c8752fdcf36
https://doi.org/10.1038/s41587-023-01674-2
https://doi.org/10.1038/s41587-023-01674-2
Autor:
Lihong Liu, Sho Iketani, Yicheng Guo, Jasper F.-W. Chan, Maple Wang, Liyuan Liu, Yang Luo, Hin Chu, Yiming Huang, Manoj S. Nair, Jian Yu, Kenn K.-H. Chik, Terrence T.-T. Yuen, Chaemin Yoon, Kelvin K.-W. To, Honglin Chen, Michael T. Yin, Magdalena E. Sobieszczyk, Yaoxing Huang, Harris H. Wang, Zizhang Sheng, Kwok-Yung Yuen, David D. Ho
Publikováno v:
Nature. 602:676-681
The Omicron (B.1.1.529) variant of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) was only recently detected in southern Africa, but its subsequent spread has been extensive, both regionally and globally1. It is expected to become domin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e47f456cf58551b48a080cb84b0362
https://doi.org/10.1038/s41586-021-04388-0
https://doi.org/10.1038/s41586-021-04388-0
Autor:
Christoph H. Gruber, Harris H. Wang, Nathan I. Johns, Jimin Park, Peter Francis Doubleday, Zrinka Raguz Nakic, Aarti Krishnan, Evgeniya Schastnaya, Uwe Sauer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications, 12 (1)
Nature Communications
Nature Communications, 12 (1)
Protein serine/threonine/tyrosine (S/T/Y) phosphorylation is an essential and frequent post-translational modification in eukaryotes, but historically has been considered less prevalent in bacteria because fewer proteins were found to be phosphorylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b174aa0c5e19f78d1f00333a4234bf8c
https://doaj.org/article/2160c240cd0443caaf59b15567610f60
https://doaj.org/article/2160c240cd0443caaf59b15567610f60