Cohort design and natural language processing to reduce bias in electronic health records research.

Autor: Khurshid S; Division of Cardiology, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA., Reeder C; Data Sciences Platform, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA., Harrington LX; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA., Singh P; Data Sciences Platform, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA., Sarma G; Data Sciences Platform, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA., Friedman SF; Data Sciences Platform, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA., Di Achille P; Data Sciences Platform, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA., Diamant N; Data Sciences Platform, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA., Cunningham JW; Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA.; Division of Cardiology, Brigham and Women's Hospital, Boston, MA, USA., Turner AC; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Henry and Allison McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA, USA., Lau ES; Division of Cardiology, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA., Haimovich JS; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Al-Alusi MA; Division of Cardiology, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Wang X; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA., Klarqvist MDR; Data Sciences Platform, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA., Ashburner JM; Harvard Medical School, Boston, MA, USA.; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA., Diedrich C; Bayer AG, Research and Development, Pharmaceuticals, Leverkusen, Germany., Ghadessi M; Bayer AG, Research and Development, Pharmaceuticals, Leverkusen, Germany., Mielke J; Bayer AG, Research and Development, Pharmaceuticals, Leverkusen, Germany., Eilken HM; Bayer AG, Research and Development, Pharmaceuticals, Leverkusen, Germany., McElhinney A; Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA., Derix A; Bayer AG, Research and Development, Pharmaceuticals, Leverkusen, Germany., Atlas SJ; Harvard Medical School, Boston, MA, USA.; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA., Ellinor PT; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA.; Demoulas Center for Cardiac Arrhythmias, Massachusetts General Hospital, Boston, MA, USA., Philippakis AA; Data Sciences Platform, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA.; Eric and Wendy Schmidt Center, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA., Anderson CD; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Henry and Allison McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA., Ho JE; Division of Cardiology, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA., Batra P; Data Sciences Platform, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA., Lubitz SA; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA. slubitz@mgh.harvard.edu.; Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA. slubitz@mgh.harvard.edu.; Demoulas Center for Cardiac Arrhythmias, Massachusetts General Hospital, Boston, MA, USA. slubitz@mgh.harvard.edu.

Publikováno v: NPJ digital medicine [NPJ Digit Med] 2022 Apr 08; Vol. 5 (1), pp. 47. Date of Electronic Publication: 2022 Apr 08.

Automated Electronic Phenotyping of Cardioembolic Stroke.

Autor: Guan W; Cardiovascular Research Center and Cardiac Arrhythmia Service (W.G., S.K., A.T.T.L., L.X.H., S.A.L.), Massachusetts General Hospital, Boston., Ko D; Cardiovascular Research Center and Cardiac Arrhythmia Service (W.G., S.K., A.T.T.L., L.X.H., S.A.L.), Massachusetts General Hospital, Boston., Khurshid S; Cardiovascular Research Center and Cardiac Arrhythmia Service (W.G., S.K., A.T.T.L., L.X.H., S.A.L.), Massachusetts General Hospital, Boston., Trisini Lipsanopoulos AT; Cardiovascular Research Center and Cardiac Arrhythmia Service (W.G., S.K., A.T.T.L., L.X.H., S.A.L.), Massachusetts General Hospital, Boston., Ashburner JM; Cardiovascular Research Center and Cardiac Arrhythmia Service (W.G., S.K., A.T.T.L., L.X.H., S.A.L.), Massachusetts General Hospital, Boston., Harrington LX; Cardiovascular Research Center and Cardiac Arrhythmia Service (W.G., S.K., A.T.T.L., L.X.H., S.A.L.), Massachusetts General Hospital, Boston., Rost NS; Cardiovascular Research Center and Cardiac Arrhythmia Service (W.G., S.K., A.T.T.L., L.X.H., S.A.L.), Massachusetts General Hospital, Boston., Atlas SJ; Cardiovascular Research Center and Cardiac Arrhythmia Service (W.G., S.K., A.T.T.L., L.X.H., S.A.L.), Massachusetts General Hospital, Boston., Singer DE; Cardiovascular Research Center and Cardiac Arrhythmia Service (W.G., S.K., A.T.T.L., L.X.H., S.A.L.), Massachusetts General Hospital, Boston., McManus DD; Cardiovascular Research Center and Cardiac Arrhythmia Service (W.G., S.K., A.T.T.L., L.X.H., S.A.L.), Massachusetts General Hospital, Boston., Anderson CD; Cardiovascular Research Center and Cardiac Arrhythmia Service (W.G., S.K., A.T.T.L., L.X.H., S.A.L.), Massachusetts General Hospital, Boston., Lubitz SA; Cardiovascular Research Center and Cardiac Arrhythmia Service (W.G., S.K., A.T.T.L., L.X.H., S.A.L.), Massachusetts General Hospital, Boston.

Publikováno v: Stroke [Stroke] 2021 Jan; Vol. 52 (1), pp. 181-189. Date of Electronic Publication: 2020 Dec 10.

Characterizing the heterogeneity in 5-aminolevulinic acid-induced fluorescence in glioblastoma.

Autor: Almiron Bonnin DA; 1Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover.; 2Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon., Havrda MC; 1Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover.; 2Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon., Lee MC; 2Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon.; 3Department of Biology, Dartmouth College, Hanover., Evans L; 4Department of Surgery (Neurosurgery), Geisel School of Medicine at Dartmouth, Hanover.; 5Department of Neurosurgery, Dartmouth-Hitchcock Medical Center, Lebanon., Ran C; 1Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover.; 2Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon., Qian DC; 6Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire., Harrington LX; 6Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire., Valdes PA; 7Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Cheng C; 1Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover.; 2Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon.; 6Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire., Amos CI; 1Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover.; 2Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon.; 6Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire., Harris BT; 8Department of Pathology, Georgetown University Medical Center, Washington, DC., Paulsen KD; 2Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon.; 4Department of Surgery (Neurosurgery), Geisel School of Medicine at Dartmouth, Hanover.; 5Department of Neurosurgery, Dartmouth-Hitchcock Medical Center, Lebanon.; 9Thayer School of Engineering, Dartmouth College, Hanover., Roberts DW; 2Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon.; 4Department of Surgery (Neurosurgery), Geisel School of Medicine at Dartmouth, Hanover.; 5Department of Neurosurgery, Dartmouth-Hitchcock Medical Center, Lebanon.; 9Thayer School of Engineering, Dartmouth College, Hanover., Israel MA; 1Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover.; 2Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon.; 10Department of Medicine, Geisel School of Medicine at Dartmouth, Hanover; and.; 11Department of Pediatrics, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire.

Publikováno v: Journal of neurosurgery [J Neurosurg] 2019 May 24; Vol. 132 (6), pp. 1706-1714. Date of Electronic Publication: 2019 May 24 (Print Publication: 2020).

Functional network community detection can disaggregate and filter multiple underlying pathways in enrichment analyses.

Autor: Harrington LX; Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth College, Hanover 03784, USA, lia.harrington.gr@dartmouth.edu., Way GP, Doherty JA, Greene CS

Publikováno v: Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing [Pac Symp Biocomput] 2018; Vol. 23, pp. 157-167.

Cholinergic control of male mating behavior in hamsters: effects of central oxotremorine treatment.

Autor: Floody OR; Department of Psychology and Program in Neuroscience, Bucknell University, Lewisburg, PA 17837, United States. ofloody@bucknell.edu, Katin MJ, Harrington LX, Schassburger RL

Publikováno v: Pharmacology, biochemistry, and behavior [Pharmacol Biochem Behav] 2011 Dec; Vol. 100 (2), pp. 299-310. Date of Electronic Publication: 2011 Sep 10.