Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial

Autor: Bath, Philip M, Scutt, Polly, Anderson, Craig S, Appleton, Jason P, Berge, Evind, Cala, Lesley, Dixon, Mark, England, Timothy M, Godolphin, Peter J, Havard, Diane, Haywood, Lee, Hepburn, Trish, Krishnan, Kailash, Mair, Grant, Montgomery, Alan A, Muir, Keith, Phillips, Stephen J, Pocock, Stuart, Potter, John, Price, Chris, Randall, Marc, Robinson, Thompson G, Roffe, Christine, Rothwell, Peter M, Sandset, Else C, Sanossian, Nerses, Saver, Jeffrey L, Shone, Angela, Siriwardena, A Niroshan, Wardlaw, Joanna M, Woodhouse, Lisa J, Venables, Graham, Sprigg, Nikola, Amarenco, Pierre, Muir, Keith, Amoils, Shannon, Jarvis, Malcolm, Rothwell, Peter M, Sandercock, Peter, Asplund, Kjell, Baigent, Colin, Ankolekar, Sandeep, Howard, Harriet, Lysons, Christopher, Walker, Gemma, Gregory, Hayley, Kirby, James, Smithson, Jennifer, Keeling, Joanne, Frowd, Nadia, Gray, Robert, Dooley, Richard, Clarke, Wim, Robinson, Patricia, Law, Zhe Kang, Hodgson, Sheila, Millington, Adam, Sakka, Eleni, Buchanan, David, Palmer, Jeb, Shaw, D, Cobb, H, Johnson, R, Payne, T, Spaight, R, Spaight, A, Sajid, M A, Whileman, A, Hall, E, Cripps, H, Toms, J, Gascoyne, R, Wright, S, Cooper, M, Palfreman, A, Rajapakse, A, Wynter, I, Musarrat, K, Mistri, A, Patel, C, Stephens, C, Khan, S, Patras, S, Soliman, M, Elmarimi, A, Hewitt, C, Watson, E, Wahishi, I, Hindle, J, Perkin, L, Wills, M, Arif, S, Leach, S, Butler, S, O'Kane, D, Smith, C, O'Callaghan, J, Sunman, W, Buck, A, Jackson, B, Richardson, C, Wilkes, G, Clarke, J, Ryan, L, Matias, O, Mangion, D, Hardwick, A, Constantin, C, Thomas, I, Netherton, K, Markova, S, Hedstrom, A, Rushton, B, Hyde, C, Scott, J, Blair, M, Maddula, M, Donnelly, R, Keane, S, Johnson, S, McKenzie, H, Banerjee, A, Hutchinson, D, Goodhand, H, Hill, J, Mellows, K, Cheeseman, M, McTaggart, V, Foster, T, Prothero, L, Saksena, P, O'Kelly, A, Wyllie, H, Hacon, C, Nutt, H, North, J, Goffin, K, Potter, J, Wiltshire, A, Ravenhill, G, Metcalf, K, Ford, L, Langley, M, Davison, W, Subramonian, S, Magezi, F, Obi, I, Temple, N, Butterworth-Cowin, N, Oqwusu-Agyei, P, Azim, A F M, Nicolson, A, Imam, J, White, J, Wood, L, Fothergill, R, Thompson, N, Lazarus, J, Werts, H, Sztriha, L, Ho, C, McKenzie, E, Owoyele, E, Lim, J, Aeron-Thomas, J, Dockey, M, Sylvester, N, Rao, P, Bloom, B M, Erumere, E, Norman, G, Skene, I, Cuenoud, L, Howaniec, L, Boulton, O, Daboo, P, Michael, R, Al-Saadi, S, Harrison, T, Syed, H, Argandona, L, Amiani, S, Perry, R, Ashton, A, Banaras, A, Hogan, C, Watchurst, C, Elliott, E, Francia, N, Oji, N, Erande, R, Obarey, S, Feerick, S, Tshuma, S, England, E, Pocock, H, Poole, K, Manchanda, S, Burn, I, Dayal, S, McNee, K, Robinson, M, Hancock, R, South, A, Holmes, C, Steele, A, Guthrie, L B, Oborn, M, Nor, A Mohd, Hyams, B, Eglinton, C, Waugh, D, Cann, E, Wilmhurst, N, Piesley, S, Shave, S, Dutta, D, Obeid, M, Ward, D, Turfrey, J, Glass, J, Bowstead, K, Hill, L, Brown, P, Beames, S, O'Connell, S, Hughes, V, Whiting, R, Gagg, J, Hussain, M, Harvey, M, Karunatilake, D, Pusuluri, B, Witcher, A, Pawley, C, Allen, J, Foot, J, Rowe, J, Lane, C, Ragab, S, Wadams, B, Dube, J, Jupp, B, Ljubez, A, Bagnall, C, Hann, G, Tucker, L, Kelton, M, Orr, S, Harrington, F, James, A, Lydon, A, Courtauld, G, Bond, K, Lucas, L, Nisbett, T, Kubie, J, Bowring, A, Jennings, G, Thorpe, K, Mason, N, Keenan, S, Gbadomishi, L, Howcroft, D, Newton, H, Choulerton, J, Avis, J, Shaw, L, Paterson, P, Kaye, P, Hierons, S, Lucas, S, Clatworthy, P, Faulkner, B, Rannigan, L, Worner, R, Bhaskaran, B, Saulat, A, Bearne, H, Garfield-Smith, J, Horan, K, Fitzell, P, Szabo, S, Haley, M, Simmons, D, Cotterill, D, Saunders, G, Dymond, H, Beech, S, Rashed, K, Tanate, A, Buckley, C, Wood, D, Matthews, L, Board, S, Pitt-Kirby, T, Rees, N, Convery, C, Jones, P, Bryant, C, Tench, H, Dixon, M, Loosley, R, Coetzee, S, Jones, S, Sims, T, Krishnan, M, Davies, C, Quinn, L, Connor, L, Wani, M, Storton, S, Treadwell, S, Anjum, T, Somashekar, C, Chandler, A, Triscott, C, Bevan, L, Sander, M, Buckle, S, Sayed, W, Andrews, K, Hughes, L, Hughes, R, Ward, M, Pretty, A, Rosser, A, Davidson, B, Price, G, Gunson, I, Lumley-Holmes, J, Miller, J, Larden, M, Jhamat, M, Horwood, P, Boldy, R, Jenkins, C, Price, F, Harrison, M, Martin, T, Ahmad, N, Willberry, A, Stevens, A, Fotherby, K, Barry, A, Remegoso, A, Alipio, F, Maquire, H, Hiden, J, Finney, K, Varquez, R, Ispoglou, S, Hayes, A, Gull, D, Evans, R, Epstein, E, Hurdowar, S, Crossley, J, Miles, J, Hird, K, Pilbery, R, Patterson, C, Ramadan, H, Stewart, K, Quinn, O, Bellfield, R, Macquire, S, Gaba, W, Nair, A, Wilson, A, Hawksworth, C, Alam, I, Greig, J, Robinson, M, Gomes, P, Rana, P, Ahmed, Z, Anderston, P, Neal, A, Walstow, D, Fong, R, Brotheridge, S, Bwalya, A, Gillespie, A, Midgley, C, Hare, C, Lyon, H, Stephenson, L, Broome, M, Worton, R, Jackson, S, Rayessa, R, Abdul-Hamid, A, Naylor, C, Clarkson, E, Hassan, A, Waugh, D, Veraque, E, Finch, L, Makawa, L, Carpenter, M, Datta, P, Needle, A, Jackson, L, Brooke, H J, Ball, J, Lowry, T, Punnoose, S, Walker, R, Murray, V, Ali, A, Kamara, C, Doyle, C, Richards, E, Howe, J, Dakin, K, Harkness, K, Lindert, R, Wanklyn, P, Willcoxson, P, Clark-Brown, P, Mir, R

Publikováno v: The Lancet; March 2019, Vol. 393 Issue: 10175 p1009-1020, 12p

Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial

Autor: Bath, Philip M, Woodhouse, Lisa J, Appleton, Jason P, Beridze, Maia, Christensen, Hanne, Dineen, Robert A, Duley, Lelia, England, Timothy J, Flaherty, Katie, Havard, Diane, Heptinstall, Stan, James, Marilyn, Krishnan, Kailash, Markus, Hugh S, Montgomery, Alan A, Pocock, Stuart J, Randall, Marc, Ranta, Annemarei, Robinson, Thompson G, Scutt, Polly, Venables, Graham S, Sprigg, Nikola, Christensen, L M, Bentsen, L, Krarup Hansen, C, Thomsen, T T, Kruuse, C, Jensen, H H, Hansen, S S, Petrovic, V, Beridze, N, Kakabadze, N, Kherkheulidze, T, Kakabadze, D, Toidze, I, Lobjanidze, N, Akiashvili, N, Tevdoradze, A, Khizanishvili, N, Tsanava, T, Taylor, R, Iniesta, I, Kok, J, Duignan, J, Funnell, M, Cariga, P, Rodriguez, M, Watson, I J, Tennant, S, Macleod, M, Furnace, J, Gow, H, Irvine, J, Joyson, A, Nelson, S, Taylor, V, Smith, M, Bellfield, R, Hairsine, B, Davies, R, Dodd, A, Corrigan, J, Doherty, M, Ahmed, A, Denniss, C, Johnson-Holland, S, Kay, K A, Palau, R Icart, Auld, G, Daboo, P, Erande, R, Grimwood, G, Hove, D, Howaniec, L, Redjep, O, Rangasamay, R, Butt, G, Sandler, D, Reddan, J, Stafford, S, McIlmoyle, J, Maguire, S, Murphy, P, Chambers, J, Guthrie, L, Osborn, M, Steele, A, Burn, M, Benford, A, Misra, A, Hilton, D, O'Brien, E, Amis, E, Finlay, S, Mitchell, J, Geraghty, O, Harvey, K, Hazel, B, Mashate, S, Wilding, P, Sajid, M, Ball, M, Gascoyne, R, Sivakumar, R, Wright, A, Chatterjee, K, Booth, S, Eccleson, H, Kelly, C, Leason, S, Perkins, C, Bruce, D, Brown, E, Clayton, S, Garside, M, Rogers, G, Lawrence, E, Mahmood, S, Watchurst, C, Chadha, D, Glover, L, Holford, L, Smith, K, Walstow, D, Williams, R, O'Shea, L, Goodsell, J, Athulathmudali, C, Barbon, E, Namushi, R, Jacob, P, Johnson, L, Morse, D, McGhee, C, Speirs, O, Atkinson, S, Peacocke, A, Langhorne, P, Graham, R, Wright, F, McAlpine, C, Ravindrane, A, Bajoriene, M, Matter, L, Windebank, S, Giallombardo, E, Dellafera, D, Eglinton, C, Wilson, J, Broughton, D, Chapman, K, Dixon, L, Zaidi, M, Ayes, K, Kessell, J, Manawadu, D, Adegbaju, O, Aeron-Thomas, J, Anderson, K, Brigden, A, Cattermole, E, Good, J, Hassan, S, Khoromana, E, Lee-Carbon, L, Marks, K, Mckenzie, E, Sikondari, N, Cooper, M, Whysall, K, Wynter, I, Bamford, J, Hassan, A, Wanklyn, P, Kambafwile, M, Makawa, L, Waugh, D, Veraque, E, Soliman, MGG, Arif, S, Brown, R, Butler, S, Hewitt, C, Hindle, J, Pusalkar, A, Beadle, H, Chan, K, Siddiqui, M, Dangri, P, Buddha, S, Asokanathan, A, Mistri, A, Eveson, D, Musarrat, K, Manning, L, Anand, S, Christian, P, Khan, S, Patel, C, Sein, M, Banns, J, Gibson, E, Gordon, T, Gruenbeck, Y, Wong, S, Datta, P, Bateman, G, Jackson, L, Needle, A, Duodu, Y, Oliver, R, Padilla-Harris, C, Barber, M, Esson, D, Brodie, F, McInnes, C, Fotherby, K, Butler, D, Morgan, D, Preece, K, Willberry, A, Dent, M, Hammonds, F, Hunt, J, Vernon, C, O'Kane, D, Faola, F, Lai, P, O'Callaghan, J, Smith, C, Price, C, Lakey, R, Riddell, V, Smith, A, Storey, G, Munshi, S, Buck, A, Clarke, J, Gilzeane, N, Godfrey, M, Keshvara, R, Richardson, C, Roffe, J, Ryan, L, Shelton, F, Sunman, W, Tittle, A, Tomlinson, J, Whittamore, K, Wilkes, G, Owusu-Agyei, P, Temple, N, Mangion, D, Hardwick, A, Netherton, K, Nor, A Mohd, Hyams, B, Norman, S, Persad, N, Ragab, S, Dickson, C, Dube, J, Jinks, E, Knops, K, Wadams, B, Ali, K, Gaylard, J, Spurling, G, Sztriha, L, Ajao, T, Alao, M, Chan, F K, Webster, P, Howard, P, Dobson, T J, Hyatt, L, Sims, D, Cunningham, J, Esisi, B, Cassidy, T, Bokhari, M, McClelland, B, Mokoena, B, Gunathilagan, G, Jones, S, Reader, M, Thomas, G, Tilby, S, Findlay, P, Barrett, F, Leslie, F, Ross, S, Shread, I, Okwera, J, Howe, J, Harrington, F, Courtauld, G, Schofield, C, Donnelly, R, Maddula, M, Scott, J, Beavan, J, Muhidden, K, Memon, I, Clarke, M, Hedstrom, A, Mills, L, Hemsley, A, Bowring, A, Boxall, L, Kingwell, H, Keenan, S, Roughan, C, Manoj, A, Cox, P, Fletcher, G, Lopez, P, Emsley, H, Gregary, B, McLoughlin, A, Raj, S, Roffe, C, Abano, N, Barry, A, Butler, A, Carpio, R, Castro, K, Finney, K, Gomm, S, Hiden, J, Grocott, J, Lyjko, S, Maguire, H, Remegoso, A, Sanyal, R, Stevens, S, Natarajan, I, Chembala, J, Muddegowda, G, Warusevitane, A, Blight, A, Balazikova, O, Lawlor, C, Shaw, L, Button, D, Howcroft, D, Lucas, S, Madigan, B, McCann, S, Dixit, A, Barkat, A, Davis, J, Fawcett, M, Finlay, L, Guy, H, Hays, C, Hogg, V, Horsley, E, Hubbuck, C, Pringle, C, Stevenson, C, Storey, K, Thompson, T, Woodward, S, Banerjee, A, Allcock, C, Merotra, S, Douglass, C, Campbell, E, Jarapa, R, Johnes, M, Keaveney, C, Marsden, T, Naing, Z, Perez, J, Shaw, K, Black, T, Anthony, A, Clarke, C, Paterson, J, Deighton, K, Temlett, E, Blank, C, Doyle, C, Duty, S, Gill, K, Harkness, K, Kamara, C, Richards, E, Elfandi, K, Guyler, P, Harman, P, Khuoge, C, Kunhunny, S, Tysoe, S, Moynihan, B, Adedoyin, T, Chopra, N, Dayal, N, Ghatala, R, Jeyaraj, N, Jones, I, Kennedy, F, Kerin, L, Khanom, N, Lewis, S, Maheswaran, S, Montague, L, Niemierko, M, O'Reilly, J, Trippier, S, Watson, F, Wilkinson, P, Young, E, Dizayee, K, Cochrane, H, O'Connell, J, Mokoena, L, Osborne, E, Nair, A, Greig, J, Jenkins, C, Powell, J, Price, F, Chowdhury, M, Brixey, S, Hunt, L, Rands, N, Rose, G, Stoddart, S, Srinivasan, M, Motherwell, N, Shekhar, R, Fuller, T, Lankester, A, Lingwood, P, Rankin, C, Webb, H, Jupp, B, Bell, J, Hann, G, Longland, B, Ovington, C, Bhaskaran, B, Ayres, G, Bailey, C, Bearne, H, Buxton, J, Fitzell, P, Hilaire, C, Kelly, D, Szabo, S, Tomlin, D, Gamble, E, Charles, B, Kumar, R, Fluskey, T, Mellor, Z, Peters, J, Sutton, V, Kenton, A, Martin, I, Nyabadza, S, Ghosh, S, Henry, M, Kumar, B, Bruce, D, Ambulo, C, Crawford, S, Nozedar, T, Platton, M, Cvoro, V, Couser, M, McCormick, K, Wilkinson, D, Javaid, K, Hurdowar, S, Attygalle, T, Sundayi, S, Orugun, O, Crowther, H, Jolly, R, Poultney, U, Azim, A, Krasinska-Chavez, M, White, J, Sengupta, N, Margalef, J, Metiu, M G, Meenakshisundaram, S, Dealing, S, Hargroves, D, Beranova, E, Cowie, L, Rudenko, H, Thomson, A, Verrion, A, Rashed, K, Board, S, Buckley, C, Hayward, D, Jenkins, K, Keeling, E, Rowland-Axe, R, Vickers, C, Wood, D, Lehman, A, Erande, R, Patel, M, Russell, H, Rehman, H, Forrest, D, Farren, P

Publikováno v: The Lancet; March 2018, Vol. 391 Issue: 10123 p850-859, 10p

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.