Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Harriette J. Kahn"'
Autor:
Sharon Nofech-Mozes, Jacqueline Spayne, Eileen Rakovitch, Harriette J Kahn, Arun Seth, Jean-Phillippe Pignol, Lavina Lickley, Lawrence Paszat, Wedad Hanna M.D. FRCPC
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 2 (2008)
DCIS is a heterogeneous group of non-invasive cancers of the breast characterized by various degrees of differentiation and unpredictable propensity for transformation into invasive carcinoma. We examined the expression and prognostic value of 9 biol
Externí odkaz:
https://doaj.org/article/cc82661479c0441fa3c0598be1a5bf7f
Autor:
J Xu, J-A Chapman, Harriette J. Kahn, Maureen E. Trudeau, Mark Clemons, Rebecca Dent, Patti O'Brien, Baoqing Guo, Kathleen I. Pritchard, Amadeo M. Parissenti, Lois E. Shepherd, Roberta A. Jong
Publikováno v:
Cancer Research. 73:P3-14
Background: 93 patients were enrolled in sequential phase 1 and 2 trials of epirubicin (E) and docetaxel (D) given at 3 (cohort A) or 2 weekly (cohort B) intervals. We previously reported clinical (93%) and pathologic response rates (pCR 7%) as well
Autor:
Raymond M. Reilly, Curtis B. Caldwell, Harriette J. Kahn, Deborah A. Scollard, Claire M. B. Holloway, Lisa E. Ehrlich
Publikováno v:
Nuclear Medicine and Biology. 40:630-637
Introduction Our aim was to conduct a Phase I clinical trial to determine the feasibility of intraoperative detection of tumor margins in HER2 positive breast carcinoma using a hand-held γ-probe following administration of 111 In-DTPA-trastuzumab Fa
Publikováno v:
Pediatric and Developmental Pathology. 15:259-264
The D2-40 antigen is a glycosylated sialomucin that is strongly expressed by lymphatic endothelial cells. Recently we observed the expression of D2-40 on the luminal surface of pulmonary airspaces in lung sections. The aim of the study was to assess
Autor:
Wenyi Yang, Harriette J. Kahn, Tania Benatar, Yutaka Amemiya, Valentina Evdokimova, Arun Seth, Claire M. B. Holloway
Publikováno v:
Breast Cancer Research and Treatment. 133:563-573
Insulin-like growth factor binding protein 7 (IGFBP7) has been shown to be a tumor suppressor in a variety of cancers. We previously have shown that IGFBP7 expression is inversely correlated with disease progression and poor outcome in breast cancer.
Autor:
Claire M. B. Holloway, Harriette J. Kahn, Wenyi Yang, Yutaka Amemiya, Albert Yee, Pearl Lam, Arun Seth
Publikováno v:
Cancer Biology & Therapy. 8:1010-1017
In this study, we created a clinically relevant model using NOD/SCID mice engrafted with human bone fragments in both right and left flanks, and show that the human bone implants are viable and functional for more than six months. To investigate the
Autor:
Claire M. B. Holloway, Tulin Cil, C. Flynn, W. Melnick, J. Hauspy, Harriette J. Kahn, Sandra Gardner
Publikováno v:
Annals of Surgical Oncology. 15:3361-3368
Breast cancer is the most common female cancer in North America. Axillary lymph node dissection (ALND) is important for staging, prognosis, and adjuvant treatment decisions. The purpose of this study was to identify factors that affect the number of
Publikováno v:
Annals of Diagnostic Pathology. 12:67-71
Medullary thyroid carcinoma (MTC) is an uncommon thyroid cancer comprising 5% to 8% of thyroid neoplasms. In contrast to common thyroid tumors, this tumor originates from the calcitonin-producing C cells. Regional metastases to cervical lymph nodes o
Publikováno v:
The Breast Journal. 13:122-129
HER2/neu is overexpressed in about 20% of invasive breast carcinomas. Numerous studies have shown that there is high level of concordance between the HER2/neu status of the primary breast cancer and the metastases of a given patient. Recently, change
Autor:
Joyce M. Slingerland, Ping Sun, Steven A. Narod, Ludger Hengst, Isabel Chu, Harriette J. Kahn, Angel Arnaout, Cheng Keat Tan, Wedad Hanna, Jun Sun
Publikováno v:
Cell. 128(2):281-294
SummaryThe kinase inhibitor p27Kip1 regulates the G1 cell cycle phase. Here, we present data indicating that the oncogenic kinase Src regulates p27 stability through phosphorylation of p27 at tyrosine 74 and tyrosine 88. Src inhibitors increase cellu