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This useful book reviews and analyzes the rigorous scientific, regulatory, and clinical testing and evaluation applied to the widely used food additive aspartame. In one compact volume you gain access to extensive information illustrating the increas
Publikováno v:
Nutrition Today. 39:235-244
Autor:
Harriett H. Butchko, W.Wayne Stargel
Publikováno v:
Regulatory Toxicology and Pharmacology. 34:221-233
Prior to marketing, the safety of the high-intensity sweetener aspartame for its intended uses as a sweetener and flavor enhancer was demonstrated by the results of over 100 scientific studies in animals and humans. In the postmarketing period, the s
Publikováno v:
Regulatory Toxicology and Pharmacology. 20:105-118
Postmarketing surveillance of consumption and of anecdotal reports of adverse health effects has been recognized by a number of regulatory authorities as a potentially useful method to provide further assurance of the safety of new food additives. Su
Autor:
W. Wayne Stargel, Jennifer Zervakis, Susan S. Schiffman, Harriett H. Butchko, Brevick G. Graham, Elizabeth A. Sattely-Miller
Publikováno v:
Chemical senses. 28(3)
The purpose of the present study was to determine the effect of repeated presentation of the same sweet stimulus on sweetness intensity ratings. The sweet stimuli tested in this study were binary and ternary blends of 14 sweeteners that varied widely
Autor:
Friedrich K. Trefz, Dale A. Mayhew, C. Phil Comer, Donald L. Schomer, Bennett A. Shaywitz, John A. Thomas, George L. Blackburn, Adalbert Koestner, Arthur S. Leon, W. Wayne Stargel, Thomas R. Tephly, Harriett H. Butchko, Ian C. Munro, Raif S. Geha, Edward J. Novotny, Susan S. Schiffman, Paul A. Spiers, Christian Benninger, Kenneth E. McMartin, Andrew G. Renwick, Charles L. Mendenhall, Leo M. J. de Sonneville, Zsolt Hertelendy, George U. Liepa
Publikováno v:
Scopus-Elsevier
Over 20 years have elapsed since aspartame was approved by regulatory agencies as a sweetener and flavor enhancer. The safety of aspartame and its metabolic constituents was established through extensive toxicology studies in laboratory animals, usin
Autor:
F N Kotsonis, Harriett H. Butchko
Publikováno v:
Journal of the American College of Nutrition. 10(3)
This article discusses the acceptable daily intake (ADI) and the postmarketing surveillance of consumption levels for a food additive, using the widely used food additive aspartame (APM, L-aspartyl-L-phenylalanine methyl ester) as an example. The saf
Autor:
Harriett H. Butchko
Publikováno v:
Biological Psychiatry. 36:206-207
Autor:
HARRIETT H. BUTCHKO, IRVIN STRATHMAN
Publikováno v:
Pediatrics. 84:750-750
This letter is prompted by a call from a pediatrician attending a child who had ingested 50 Equal tablets containing NutraSweet brand sweetener (aspartame). This physician expressed concern about treatment for this "overdose." Although aspartame is a