Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Harriett C. Rea"'
Autor:
Thomas A. Kent, James M. Tour, Vladimir Berka, Ah-Lim Tsai, Lizanne G. Nilewski, Kimberly Mendoza, Harriett C Rea, Roderic H. Fabian, William Dalmeida, Pitchaiah Mandava, William K.A. Sikkema, Paul J. Derry
Publikováno v:
Frontiers in Neurology
Frontiers in Neurology, Vol 9 (2018)
Frontiers in Neurology, Vol 9 (2018)
Introduction While oxidative stress can be measured during transient cerebral ischemia, antioxidant therapies for ischemic stroke have been clinically unsuccessful. Many antioxidants are limited in their range and/or capacity for quenching radicals a
Autor:
Kathia M. Johnson, Claire E. Hulsebosch, Jose R. Perez-Polo, K. Werrbach-Perez, Donald S. Prough, Geda Unabia, Harriett C. Rea, Guo-Ying Xu, Margaret A. Parsley, Douglas S. DeWitt, A. A. Paulucci-Holthauzen
Publikováno v:
Journal of Neuroscience Research. 94:27-38
In rodent models of traumatic brain injury (TBI), both Interleukin-1β (IL-1β) and tumor necrosis factor-α (TNFα) levels increase early after injury to return later to basal levels. We have developed and characterized a rat mild fluid percussion m
Autor:
Thomas A. Kent, Roderic H. Fabian, Harriett C Rea, Cenk Ayata, Pitchaiah Mandava, William Dalmeida
Publikováno v:
Stroke. 48
Introduction: Failures to translate pre-clinical results have been discouraging. We have contended that stroke is too heterogeneous with respect to factors influencing outcome to expect small studies to be balanced. It is not only difficult to contro
Autor:
Lizanne G. Nilewski, Thomas A. Kent, William K.A. Sikkema, Pitchaiah Mandava, William Dalmeida, Harriett C Rea, Roderic H. Fabian, James M. Tour
Publikováno v:
Stroke. 48
Introduction: While oxidative stress mediates many of the pathologies in stroke, antioxidant therapies have been unsuccessful. Current antioxidants are limited either by a narrow range of radicals quenched or by low capacity. Some can yield toxic int
Autor:
Harriett C. Rea, Heidi Spratt, Donald S. Prough, Guo-Ying Xu, Claire E. Hulsebosch, Margaret A. Parsley, Geda Unabia, Jose R. Perez-Polo, Douglas S. DeWitt, Kathia M. Johnson
Publikováno v:
Journal of Neuroscience Research. 93:549-561
One of the criteria defining mild traumatic brain injury (mTBI) in humans is a loss of consciousness lasting for less than 30 min. mTBI can result in long-term impairment of cognition and behavior. In rats, the length of time it takes a rat to right
Publikováno v:
International Journal of Developmental Neuroscience. 31:398-405
Neonatal hypoxia-ischemia (HI) affects 60% of low birth weight infants and up to 40% of preterm births. Cell death and brain injury after HI have been shown to cause long-lasting behavioral deficits. By using a battery of behavioral tests on second g
Publikováno v:
Journal of Proteome Research. 5:2396-2404
Perinatal hypoxia/ischemia (HI) is a common cause of neurological deficits in children. Our goal was to elucidate the underlying mechanisms that contribute to the neurological sequelae of HI-induced brain injury. HI was induced by permanent ligation
Autor:
J. Regino Perez-Polo, Olivera Nesic-Taylor, Harriett C. Rea, David K. Rassin, Jingxin Qiu, Xiaoming Hu, F. Roderick Fabian
Publikováno v:
Journal of Neurochemistry. 93:26-37
Perinatal hypoxia/ischemia (HI) is a common cause of neurological deficits in children. Interleukin-1 (IL-1) activity has been implicated in HI-induced brain damage. However, the mechanisms underlying its action in HI have not been characterized. We
Publikováno v:
Neurotoxicology and Teratology. 37:85-86
Autor:
David K. Rassin, Jingxin Qiu, Harriett C. Rea, Marjorie R. Grafe, J. Regino Perez-Polo, Xiaoming Hu
Publikováno v:
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 21(7)
Hypoxic brain injury during fetal or neonatal development leads to damaged immature neurons and can result in cognitive or behavioral dysfunction. Hyperoxia therapy (treatment with oxygen) is commonly applied to infants with signs of perinatal hypoxi