Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Harriet P Lo"'
Autor:
Kerrie-Ann McMahon, David A Stroud, Yann Gambin, Vikas Tillu, Michele Bastiani, Emma Sierecki, Mark E Polinkovsky, Thomas E Hall, Guillermo A Gomez, Yeping Wu, Marie-Odile Parat, Nick Martel, Harriet P Lo, Kum Kum Khanna, Kirill Alexandrov, Roger Daly, Alpha Yap, Michael T Ryan, Robert G Parton
Publikováno v:
eLife, Vol 10 (2021)
Caveolae-associated protein 3 (cavin3) is inactivated in most cancers. We characterized how cavin3 affects the cellular proteome using genome-edited cells together with label-free quantitative proteomics. These studies revealed a prominent role for c
Externí odkaz:
https://doaj.org/article/ec3b060033e84fb68b9e5ab9f7821ac0
Autor:
Zherui Xiong, Harriet P Lo, Kerrie-Ann McMahon, Nick Martel, Alun Jones, Michelle M Hill, Robert G Parton, Thomas E Hall
Publikováno v:
eLife, Vol 10 (2021)
Protein interaction networks are crucial for complex cellular processes. However, the elucidation of protein interactions occurring within highly specialised cells and tissues is challenging. Here, we describe the development, and application, of a n
Externí odkaz:
https://doaj.org/article/25e12cf3bd9940f393a66eb84cdd6fd6
Autor:
Fiorella Faggi, Silvia Codenotti, Pietro Luigi Poliani, Manuela Cominelli, Nicola Chiarelli, Marina Colombi, Marika Vezzoli, Eugenio Monti, Federica Bono, Giovanni Tulipano, Chiara Fiorentini, Alessandra Zanola, Harriet P Lo, Robert G Parton, Charles Keller, Alessandro Fanzani
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130287 (2015)
The purpose of this study was to investigate whether MURC/cavin-4, a plasma membrane and Z-line associated protein exhibiting an overlapping distribution with Caveolin-3 (Cav-3) in heart and muscle tissues, may be expressed and play a role in rhabdom
Externí odkaz:
https://doaj.org/article/10470ccca75c46a0a94cd37c8e00d324
Autor:
Natasha Chaudhary, Guillermo A Gomez, Mark T Howes, Harriet P Lo, Kerrie-Ann McMahon, James A Rae, Nicole L Schieber, Michelle M Hill, Katharina Gaus, Alpha S Yap, Robert G Parton
Publikováno v:
PLoS Biology, Vol 12, Iss 4, p e1001832 (2014)
Several studies have suggested crosstalk between different clathrin-independent endocytic pathways. However, the molecular mechanisms and functional relevance of these interactions are unclear. Caveolins and cavins are crucial components of caveolae,
Externí odkaz:
https://doaj.org/article/b65d5687fee24cb6b8b50d7a8d75d575
Autor:
James Rae, Frank Fontaine, Angela A Salim, Harriet P Lo, Robert J Capon, Robert G Parton, Sally Martin
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22868 (2011)
Mammalian cells store excess fatty acids as neutral lipids in specialised organelles called lipid droplets (LDs). Using a simple cell-based assay and open-source software we established a high throughput screen for LD formation in A431 cells in order
Externí odkaz:
https://doaj.org/article/96ae10034784403f844ec47755507e46
Autor:
Yeping Wu, Ye-Wheen Lim, David A. Stroud, Nick Martel, Thomas E. Hall, Harriet P. Lo, Charles Ferguson, Michael T. Ryan, Kerrie-Ann McMahon, Robert G. Parton
Publikováno v:
Developmental Cell. 58:376-397.e4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e30b4c8e711f9757cfe9f6eb12ba1bf5
https://doi.org/10.1016/j.devcel.2023.02.004
https://doi.org/10.1016/j.devcel.2023.02.004
Autor:
Michele Bastiani, Harriet P. Lo, Jan Steyaert, Rachel S. Gormal, Els Pardon, Merja Joensuu, Srikanth Budnar, Adekunle T. Bademosi, James Rae, Ailisa Blum, Jean Giacomotto, Pranesh Padmanabhan, Frederic A. Meunier, Geoffrey J. Goodhill, Alpha S. Yap, Tristan P. Wallis, Massimo A. Hilliard, Walter G. Thomas, Ravikiran Kasula, Robert G. Parton, Charles Ferguson, Sean Coakley
Publikováno v:
Proc Natl Acad Sci U S A
None of the current superresolution microscopy techniques can reliably image the changes in endogenous protein nanoclustering dynamics associated with specific conformations in live cells. Single-domain nanobodies have been invaluable tools to isolat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d015bc888a680e98a149ee7b2bbde934
https://doi.org/10.1073/pnas.2007443117
https://doi.org/10.1073/pnas.2007443117
Autor:
Michael T. Ryan, Yang Wu, Nick Martel, Robert G. Parton, Yi Chieh Lim, Thomas E. Hall, David A. Stroud, Harriet P. Lo, Katie L. McMahon, C. Ferguson
Caveolae have been linked to many biological functions, but their precise roles are unclear. Using quantitative whole cell proteomics of genome-edited cells, we show that the oxidative stress response is the major pathway dysregulated in cells lackin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9c04abb950e636c0d06e773bfeab76
https://doi.org/10.21203/rs.3.rs-963423/v1
https://doi.org/10.21203/rs.3.rs-963423/v1
Autor:
Nick Martel, Harriet P. Lo, Mark E. Polinkovsky, Yann Gambin, Kirill Alexandrov, Robert G. Parton, Roger J. Daly, Kerrie-Ann McMahon, Michele Bastiani, Thomas E. Hall, Michael T. Ryan, Vikas A. Tillu, Guillermo A. Gomez, Kum Kum Khanna, Emma Sierecki, David A. Stroud, Marie-Odile Parat, Yeping Wu, Alpha S. Yap
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Caveolae-associated protein 3 (cavin3) is inactivated in most cancers. We characterized how cavin3 affects the cellular proteome using genome-edited cells together with label-free quantitative proteomics. These studies revealed a prominent role for c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97672dc3a117bb49f6e2519d301cbb74
https://elifesciences.org/articles/61407
https://elifesciences.org/articles/61407
Autor:
Nick Martel, Vikas A. Tillu, Emma Sierecki, Thomas E. Hall, Alpha S. Yap, Kirill Alexandrov, Yeping Wu, Kum Kum Khanna, Roger J. Daly, David A. Stroud, Marie-Odile Parat, Mark E. Polinkovsky, Michele Bastiani, Guillermo A. Gomez, Robert G. Parton, Harriet P. Lo, Michael T. Ryan, Kerrie-Ann McMahon, Yann Gambin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a094586228557d839dc3f7149a2cf2d
https://doi.org/10.7554/elife.61407.sa2
https://doi.org/10.7554/elife.61407.sa2